Doctor insights on:
Adrenal Gland Disorders Congenital Adrenal Hyperplasia
Missing enzyme: There are different types. They all involve a deficiency of an enzyme needed in cortisol production. Since the pituitary senses there isn't enough cortisol, it keeps trying to make the adrenals make cortisol. But because that enzyme is missing, the building blocks of cortisol build up. These substances get turned into androgens - male hormones - and cause abnormalities in sexual development. ...Read moreSee 2 more doctor answers
What is the definition or description of: Adrenal gland disorders? ANS: I specialize in these and there are more than 100. It is as disorder that has its origin in the adrenal gland. Some are congenital, some acquired, some due to infections, some do to not enough hormone, some due to too much, some due to cancer, some due to medications, some due to immune problems, ...Read more
Congenital adrenal hyperplasia -non classical kind, what are some remedies to help with side effects of disease and medicine like steroids?
Adrenal hyperplasia: The commonest type of congenital adrenal hyperplasia is caused by deficiency of 21 hydroxylase, classical type presents at birth, but non classical may present later in early childhood or during puberty.It is difficult to answer all about it, but some salt depleted patients need to be on steroids and the patints need to be monotored for other defects, it should be trated by a pediatric endocrinologist. ...Read more
See below: It is a collection of genetic conditions that limit your adrenal glands' ability to make certain vital hormones. In most cases of congenital adrenal hyperplasia, the adrenal glands don't produce enough cortisol. The production of two other classes of hormones also may be affected, including mineralocorticoids (for example, aldosterone) and androgens (for example, testosterone). ...Read more
Congenital adrenal hyprplasis is an inherited disorder. Genetic screening can detect persons with the abnormal gene. Prenatal diagnosis can be made. Please consult this site for more information.
http://www. Nlm. Nih. Gov/medlineplus/ency/article/000411.htm. ...Read more
? Quickly?: The diagnosis implys a genetic abnormality that will last a lifetime. It can be managed over time with the aid of metabolic disease specialists working in conjunction with your local source of health care. Daily medication & scheduled followup tests and exams will gauge the progress. ...Read more
Virilization: In the classic form newborn girls will often have ambiguous looking genitalia because of intrauterine exposure to their own overproduction of androgens. Can't really see it in a newborn boy. In non-classical early pubic hair in both sexes can be presenting feature. As kids grow older other things may warrant checking like recalcitrant acne (both sexes) or irregular periods/hirsutism in girls. ...Read moreSee 1 more doctor answer
Male or Female?: This would depend on the age and sex of the patient in addition to the degree of severity. If cortisol response is normal and a male is affected, often times steroid suppression is stopped after puberty. This is more complicated in females who may otherwise suffer from irregular periods, hirsutism, recalcitrant acne. They may need treatment through adulthood. Please discuss with endocrinologist. ...Read more
It varies: Persons with the most common form of congenital adrenal hyperplasia (cah) have a predisposition to make extra testosterone. For girls can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at birth. Some girls can also have "salt wasting". Girls can also have somewhat masculinized behaviors. Testosterone levels can be lowered by therapy. Www. Caresfoundation. Org. ...Read more
Oh, now I know CAH: Previous answer, I thought it meant chronic active hepatitis. Yes, a girl or boy can be born with cong adrenal hyperplasia; this refers to a group of inherited disorders of the adrenal gland, where there is a lack of a hormone needed to make certain steroid hormones. Male sex characteristics may appear earlier than normal. Time for a pediatric endocrinologist, if there is any question of this. ...Read more
Autosomal recessive: You and the baby's father are both carriers for this disorder. Therefore neither of you actually has it. Please get genetic counseling because your next children will all have a 25% chance of being born with cah. Should your child want children of his/her own, all of them will be carriers. Cah would only happen in your grandchild if your daughter/son's partner is also a carrier or has cah. ...Read moreSee 1 more doctor answer
Yes, but there is:
Effective treatment. You should be concerned but know that the disorder can be treated and you should follow your doctor's advice closely. Please read the information on this site for reassurance and advice.
http://www. Mayoclinic. Com/health/congenital-adrenal-hyperplasia/ds00915. ...Read more
Please help us. Our boy has congenital adrenal hyperplasia. What can we do to learn more about it?
Start @endocrinology: Usually, children with congenital adrenal hyperplasia are referred to a pediatric endocrinologist for initial assessment and management--not all cases are the same! It is an ongoing condition that you will need to become familiar with--and you will, with time. There are reputable internet resources such as webmd that may help, and the endocrinologists also probably have some resources for you. ...Read moreSee 2 more doctor answers
This disease results from deficiency of an enzyme, 21 hydroxylase, that is essential for synthesis of adrenal hormones. Block in the synthesis of glucoroticoids causes excess production of male sex hormones. See this site for more information.
http://www. Ncbi. Nlm. Nih. Gov/pubmedhealth/pmh0001448/. ...Read more
Classic or non?: Classic cah is diagnosed mostly on newborn screening. It results from a block in the synthesis of cortisol and usually also aldosterone. Females will often have ambiguous genitalia. Males don't look different. Permanent replacement with Hydrocortisone & Fludrocortisone (may not need past childhood) are needed for sustaining life and salt balance. Pediatric endocrinologists follow very closely. ...Read moreSee 1 more doctor answer
Yes: Persons with the most common form congenital adrenal hyperplasia (cah) have a predisposition to making extra testosterone. For girls this can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at the time of birth. Girls can also have somewhat masculinized behaviors. The testosterone levels can be lowered by therapy. Boys do not have genital or behavioral issues. ...Read more
CAH: This is due to the lack of an enzyme needed for the adrenals to make cortisol and aldosterone. The body then uses the precursors to make androgen (male hormones) instead. Symptoms for girls: deep voice, abnormal menstruation, early appearance of pubic/armpit hairs, genitials looking both male and female...For boys: deep voice, enlarged penis, small testes, early appearance of pubic, armpit hair... ...Read moreSee 1 more doctor answer