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Doctor insights on: Adrenal Desiccated Standard Process

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Would standard process adrenal supplements (drenatrophin pmg and adrenal desiccated) affect labs – cmp, tsh, free t3, (liothyronine) free t4?

Would standard process adrenal supplements (drenatrophin pmg and adrenal desiccated) affect  labs – cmp, tsh, free t3, (liothyronine) free t4?

Adrenal supplements: 46F asks about lab effects of adrenal supplements on CMP,TSH,FT3 and Free T4. This has likely never been studied as there is no regulation of adrenal supplements & makers can put anything in them until a bunch gets sick & reported to FDA. I would avoid these unless you need to waste money. I would also avoid a Dr who prescribes them. But need more information. Consult with me. ...Read more

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Thyroid U/S showed L thyroid gland heterogeneous hypoechoic nodule w/ mind internal vascularity. what does all this mean? FNA recommended.

Thyroid U/S showed L thyroid gland heterogeneous hypoechoic nodule w/ mind internal vascularity. what does all this mean? FNA recommended.

Means abnormal test: Ultrasound is a commonly used test for detection of Throid nodules which are quite common. So when the ultrasound shows a Thyroid nodule, it needs to be monitored and often a Biopsy is required to find out if the nodule is benign or cancerous. FNA is one such technique for obtaining a biopsy for making a diagnosis. ...Read more

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Is adrenal insufficiency after pituitary tumor removal permanent? How long before most usually gain pituitary function for acth back?

Is adrenal insufficiency after pituitary tumor removal permanent?  How long before most usually gain pituitary function for acth back?

Sometimes: It is really quite variable when the pituitary function restarts after the operation. It often depends on how much was removed. Unfortunately, sometimes it is permanent. Check with your neurosurgeon for more details. ...Read more

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For patients with partial adrenal insufficiency, does hydrocortisone replacement of 20-30 mg daily cause iatrogenic cushings given that the pituitary and adrenals still function to some degree?

For patients with partial adrenal insufficiency, does hydrocortisone replacement of 20-30 mg daily cause iatrogenic cushings given that the pituitary and adrenals still function to some degree?

Depends: It really depeds what you mean by cushings. You may get some of the characteristics..Weight gain, immune dysfunction, but the classic physical signs are likely absent. The dose of 20-30 mg of hc is actually a bit above the "physiologic " dose of hc that would be similar to what the adrenals normally produce. As a result, the pituitary/adrenal are essentially shut down. ...Read more

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What is the significance of radioactive iodine scan in various throid diseases like myxedema, hashimoto's thyroiditis and graves disease?

What is the significance of radioactive iodine scan in various throid diseases like myxedema, hashimoto's thyroiditis and graves disease?

Hot vs. cold nodule: Iodine uptake by thyroid tissue depends on functioning cells. The most common use for thyroid scan is to assess if a nodule is functional or not. A functional/hot nodule may cause hyperthyroidism but is not likely to be malignant. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003829.htm. ...Read more

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15yr old male,Adrenal pheochromocytoma with liver and lung metastasis.MIBG nuclide positive. is there’s any effective therapy besides chemo?

15yr old male,Adrenal pheochromocytoma with liver and lung metastasis.MIBG nuclide positive. is there’s any effective therapy besides chemo?

Pheochromocytoma: Adrenal pheochromocytoma is a rare cancer. Treatment options include surgical removal of primary tumor. Chemotherapy and radiation therapy is utilized with metastatic disease. Here is a reference from the NIH National Cancer Institute: https://www.cancer.gov/types/pheochromocytoma/patient/pheochromocytoma-treatment-pdq#link/_126_toc ...Read more

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Colon cancer pt. old ct- nodule on left adrenal gland. ( was not met). New ct- new adrenal nodule . Are these the same or diffetent ones, ?

Must compare CT's: The best way to tell if these are the same nodule or if this is a new nodule would be to have the radiologist or your oncologist compare the CT's side-by-side. It may be obvious that they are or are not the same nodule. If it is not obvious, then further testing may be necessary, perhaps even a biopsy of the nodule if it is worrisome. Good luck. ...Read more

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1 CM pituitary neoplasm, stable but has been called tumor, hypophysitis, nothing, leading to $1ks of mris with no certainty as to diagnosis of pituitary or partial adrenal insuff, biopsy worth risks?

1 CM pituitary neoplasm, stable but has been called tumor, hypophysitis, nothing, leading to $1ks of mris with no certainty as to diagnosis of pituitary or partial adrenal insuff, biopsy worth risks?

Discuss with doc: There are tumors in this region that grow briefly and stop, causing no interference with life other than the stress involve with knowing it might. It can be a very difficult area to get to without causing injury to sensitive structures that make and release hormones. Cautious monitoring of the tumor (MRI) and hormones (blood tests) with the neurosurgeon working with the endo doc is the safest appr. ...Read more

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My hysterectomy biopsy reports mixed phase glands highly suggestive of exogenous hormone therapy. What does this mean?

My hysterectomy biopsy reports mixed phase glands highly suggestive of exogenous hormone therapy. What does this mean?

Description: the glands inside the lining of the uterus reflect exposure to estrogen or progesterone and depends on the hormones that have the higher influence, determine the type of glands. for women that are overweight they may have excessive estrogen exposure (ur fat cells make more estrogen), it may show that effect. Its not concerning. bet wishes dr M ...Read more

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Will T3 (liothyronine) cure adrenal insufficiency?

Will T3 (liothyronine) cure adrenal insufficiency?

No: Adrenal insufficiency is the result of the failure of the adrenal glands to make cortisol. T3 (liothyronine) will not treat adrenal insufficiency because it is a thyroid hormone. ...Read more

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Some research suggests patients with cushings can have positive anti-pituitary antibodies targeting acth producing cells and this autoimmunity can stimulate acth adenoma formation. Is this correct?

Some research suggests patients with cushings can have positive anti-pituitary antibodies targeting acth producing cells and this autoimmunity can stimulate acth adenoma formation.  Is this correct?

Doubt it: People with pituitary adenomas of all sorts tend to have pituitary autoantibodies but these can't cause the mutations that cause the tumors ; are probably just the result for the normal gland being damaged. Since the type of tumor has no correlation with antibody presence, this supports this common-sense idea. New review pituitary. 15(4):490-4, 2012 dec. ...Read more

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In a new state. Autonomic dz is pots. Pit, liver, ovary adenomas. Thyroid has new solid nodules and nodes. Only bx'd node. ?Ask for excision?

In a new state. Autonomic dz is pots. Pit, liver, ovary adenomas. Thyroid  has new solid nodules and nodes. Only bx'd node. ?Ask for excision?

Thyroid nodules: I know more about pots than thyroid but in general if you have a node biopsied, if there is not diagnosis, they will likely biopsy nodule to determine whether to excise. If there is a diagnosis based on node biopsy, that will lead to best recommendation. Decision depends on the pathology and extent of tissue involved. If hyperthyroid, that can explain what was diagnosed as pots, as not pots. ...Read more

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Thyroid biopsy results Showing minute fragment of thyroid tissue w/ hemosiderin-laden macrophages & blood elements most consistent w/follicular lesion?

Thyroid biopsy results Showing minute fragment of thyroid tissue w/ hemosiderin-laden macrophages & blood elements most consistent w/follicular lesion?

Thyroid biopsy: What is your question? Sounds to me like you have a lesion of the thyroid follicle. But they may have missed something else. Why was biopsy being done? Take to the Dr who did it as they know you best. ...Read more

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TSI bloodwork test or Thyroid Uptake test with the radioisotopes? Benefits/risks, pros/cons? Are they interchangeable as diagnostic tool for graves?

TSI bloodwork test or Thyroid Uptake test with the radioisotopes? Benefits/risks, pros/cons? Are they interchangeable as diagnostic tool for graves?

Thyroid: The first thing you must do is have your doctor order the thyroid labs once he/she has taken a full history and physical exam. The first thing would be to order the thyroid labs and if they are abnormal the radiology program will look for problems in your thyroid. Do not get too concerned for now - all may be OK. If not appropriate care will be given after discussion with you. Keep me posted! ...Read more