Doctor insights on:
Adrenal Cortex Vs Adrenal Medulla
Rather 3 not 1: In a nutshell: 1- Cortisol, which is cortisone important for several metabolic functions, its release is regulated by the pituitary gland in the brain, 2- Aldosterone, plays a role in controlling blood pressure and balancing salts in circulation, and 3- acts a secondary site for producing Androgens, as testosterone and others, which have several effects on muscle mass and cell growth,
No: Do not waste your money.Get a more detailed answer ›
Shrinks down: If you do not use a gland, it tends to atrophy, or shrink. If you take steroid pills, your adrenals do not need to produce any, and the glands atrophy. The cells, however, do not die, so they will come back, but it can take time, depending on how long you were on steroids and what dose.
How much? How long?: It depends on the steroids potency (they differ), the length of time you take it, and the amount you are taken. Very modest suppression can occur within a week, because acth production by the pituitary will decrease, but reawaken in a couple of days. However high doses for along period (1mo) will atrophy the adrenal gland and you will need to taperm commencing with an alternate day regimen.
Adrenals: This is news to me. I cannot think of any physiologic reason. And any "enlargement" would not be noticeable on a scan.
Adrenal cortex: If you have addison's disease, you will lose production of cortisol, and often aldosterone (na/k balance) too. Epinephrine is not usually affected. Beware of the diagnosis of "adrenal fatigue". Adrenals respond to the situation at hand. They can fail (i.e. Addison's), but don't usually fatigue. If you are being told this, see an endocrinologist to make sure about the diagnosis.
Addisons disease is caused by decreased functioning of the adrenal cortex. What causes the decreased functioning?
Nothing: The adrenal medulla produces cathecolamines which are stress hormones stimulated by the automated nervous system under control of the hypothalamus which is the unconscious part of the brain. During dialysis if your blood pressure falls receptors in your circulation will signal the adrenal medulla to secrete these hormones which cause the heart to speed up and arteries to constrict.See 1 more doctor answer
Suppresses it: Taking the hormone that is normally produced by the adrenal cortex means that it no longer produces it (negative feedback). If you suddenly stop taking the medication, your body needs several days to weeks to begin to make hormone again. So, if you are taking cortisol you need to taper the dose to make sure you give your glands the chance to being producing again.
Prolonged use, yes: Using steroid for a brief period of time of less than a few weeks probably won't have long term effect, but prolonged use will suppress it--it loses the ability to produce the steroid. Thus folks who need to use steroid for an extended of time often need to remain on it. The length of time varies, but using more than 3 wks typically would need a slow wean. Consult doc. Good luck.
Causing hypoadrenal: The adrenal cortex makes Hydrocortisone under the influence of acth from the pituitary. Too much cortisone will suppress the pituitary so it will not stimulate the adrenal to produce its own steroid. After taking cortisone in tapering amounts the adrenal will eventually wake up.
Yes: The Adrenal Medulla Secretes Adrenaline, (epinephrine, norepinephrine). Flight or Fight response. If your doctor is concerned (condition resulting in an abnormal or increase secretion). They can check hormones via blood and urine tests. The endocrinology doctor will follow this if you have abnormalities. These are not routine screening tests. They are done if there is a clinical indication (sxs)
Nothing: Nothing should happen to adrenal medulla.Get a more detailed answer ›
Hi doctors, regarding to zona riticulars in adrenal cortex, how do these nuclei even produce hormons while they are pyknotic, , ? Giant thank,
Sloppy language: I'm glad you're reading closely. When a pathologists says "pyknotic nucleus", that cells is very dead. Some anatomists use the term more loosely for any cell with a preponderance of heterochromatin even if it's alive. We pathologists can't use any other term and wish all anatomists would say "condensed" for such nuclei instead of "pyknotic" -- it's the term other scientists use.
No: Hi. No, the adrenal cortex produces cortisol and aldosterone. Testes and ovaries produce estrogen, progesterone, and testosterone (although very different between the two different glands (and genders), of course. In addition, there's a whole fledgling field of brain steroids, some of which are made in the brain, and some of which are derived from adrenal steroids. NOW, we're havin' FUN!
No: Hi. No, the pituitary controls the part of the adrenal cortex that makes cortisol, and is a secondary regulator of the part of the cortex that makes aldosterone. Cortisol does have influential effects on the adrenal medulla, so I guess you could say there are some downstream effects from the pituitary.
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