Top
20
Doctor insights on: Adrenal Cortex Vs Adrenal Medulla

Share
Dr. Casey Ng Dr. Ng
Urology
13 years in practice
Weill Cornell Medical College of Cornell University
1

1
What are the different layers of adrenal cortex?

What are the different layers of adrenal cortex?

3 layers: Zona glomerulosa, zona fasciculata and zona reticularis.

Cortex (Definition)

The cortex is the outer part of the brain or gray matter. It covers both the cerebrum and the cerebellum. See: http://en. Wikipedia. Org/wiki/cerebral_cortex for more details about the anatomy and ...Read more


Dr. Al Hegab Dr. Hegab
Internal Medicine - Allergy & Immunology
36 years in practice
Ain Shams University Faculty of Medicine
2

2
What hormone is produced by the adrenal cortex?

What hormone is produced by the adrenal cortex?

Rather 3 not 1: In a nutshell: 1- Cortisol, which is cortisone important for several metabolic functions, its release is regulated by the pituitary gland in the brain, 2- Aldosterone, plays a role in controlling blood pressure and balancing salts in circulation, and 3- acts a secondary site for producing Androgens, as testosterone and others, which have several effects on muscle mass and cell growth,

Dr. David Geffner Dr. Geffner
Internal Medicine - Endocrinology
50 years in practice
Georgetown University School of Medicine
3
Dr. Philip Kern Dr. Kern
Internal Medicine - Endocrinology
39 years in practice
New York Medical College
4

4
What occurs to the adrenal cortex if you take to much steroids?

What occurs to the adrenal cortex if you take to much steroids?

Shrinks down: If you do not use a gland, it tends to atrophy, or shrink. If you take steroid pills, your adrenals do not need to produce any, and the glands atrophy. The cells, however, do not die, so they will come back, but it can take time, depending on how long you were on steroids and what dose.

Dr. Thomas Namey Dr. Namey
Internal Medicine - Rheumatology
44 years in practice
Washington University School of Medicine
5

5
What happens to the adrenal cortex if you take too much steroids?

How much? How long?: It depends on the steroids potency (they differ), the length of time you take it, and the amount you are taken. Very modest suppression can occur within a week, because acth production by the pituitary will decrease, but reawaken in a couple of days. However high doses for along period (1mo) will atrophy the adrenal gland and you will need to taperm commencing with an alternate day regimen.

Dr. Andrew Germanovich Dr. Germanovich
Pain Management
9 years in practice
Midwestern University Chicago College of Osteopathic Medicine
6

6
Could you tell me what happens to the adrenal cortex if you take to much steroids?

Adrenal suppression: Taking large dose of steroids orally for a long time and suddenly stopping them may lead to adrenal crisis and death. This is manifested as shock that doesn't respond to common blood pressure-raising medications.

Dr. Philip Kern Dr. Kern
Internal Medicine - Endocrinology
39 years in practice
New York Medical College
7

7
Why does the adrenal cortex of adrenal glands enlarge during the summer in females?

Adrenals: This is news to me. I cannot think of any physiologic reason. And any "enlargement" would not be noticeable on a scan.

Dr. Philip Kern Dr. Kern
Internal Medicine - Endocrinology
39 years in practice
New York Medical College
8

8
If the adrenal cortex is not working properly does that means all of its hormones are affected?

If the adrenal cortex is not working properly does that means all of its hormones are affected?

Adrenal cortex: If you have addison's disease, you will lose production of cortisol, and often aldosterone (na/k balance) too. Epinephrine is not usually affected. Beware of the diagnosis of "adrenal fatigue". Adrenals respond to the situation at hand. They can fail (i.e. Addison's), but don't usually fatigue. If you are being told this, see an endocrinologist to make sure about the diagnosis.

Dr. Philip Kern Dr. Kern
Internal Medicine - Endocrinology
39 years in practice
New York Medical College
9

9
Addisons disease is caused by decreased functioning of the adrenal cortex. What causes the decreased functioning?

Addisons disease is caused by decreased functioning of the adrenal cortex. What causes the decreased functioning?

Addison's: There are a number of causes. Autoimmunity is common. Just as Hashimoto's causes decreased function of the thyroid, autoimmunity can cause Addison's disease. Other causes are Tb, hemorrhage (following surgery or severe infection), tumors. Or it can be secondary to pituitary problems.

Dr. Eduardo Haddad Dr. Haddad
Internal Medicine - Nephrology & Dialysis
42 years in practice
Federal University of Rio de Janeiro Faculty of Medicine
10

10
What exactly happens to the adrenal medulla in dialysis patients?

What exactly happens to the adrenal medulla in dialysis patients?

Nothing: The adrenal medulla produces cathecolamines which are stress hormones stimulated by the automated nervous system under control of the hypothalamus which is the unconscious part of the brain. During dialysis if your blood pressure falls receptors in your circulation will signal the adrenal medulla to secrete these hormones which cause the heart to speed up and arteries to constrict.

See 1 more doctor answer
Dr. Richard Orr Dr. Orr
Surgery - Oncology
40 years in practice
University of South Florida College of Medicine
11

11
What is the adrenal medulla?

What is the adrenal medulla?

The central core: The adrenal is actually to glands in one! The outer part (cortex) makes steroid hormones. The central part (medulla) makes Epinephrine and norepinephrine. These are fight or flight hormones that raise pulse and BP instantaneously in response to stress.

Dr. Andrew Lipton Dr. Lipton
Holistic Medicine
26 years in practice
Pennsylvania State University College of Medicine
12

12
How does cortisone damage adrenal cortex?

How does cortisone damage adrenal cortex?

Supression: Adrenal gland produces cortisol. External sources of cortisol (cortisone) will suppress the normal adrenal function.

Dr. Lester Thompson Dr. Thompson
Pathology
29 years in practice
Loma Linda University School of Medicine
13

13
How can taking cortisone damage the adrenal cortex?

How can taking cortisone damage the adrenal cortex?

Suppresses it: Taking the hormone that is normally produced by the adrenal cortex means that it no longer produces it (negative feedback). If you suddenly stop taking the medication, your body needs several days to weeks to begin to make hormone again. So, if you are taking cortisol you need to taper the dose to make sure you give your glands the chance to being producing again.

Dr. Bac Nguyen Dr. Nguyen
Family Medicine
19 years in practice
Warren Alpert Medical School of Brown University
14

14
Does cortisone in high doses damage the adrenal cortex?

Does cortisone in high doses damage the adrenal cortex?

Prolonged use, yes: Using steroid for a brief period of time of less than a few weeks probably won't have long term effect, but prolonged use will suppress it--it loses the ability to produce the steroid. Thus folks who need to use steroid for an extended of time often need to remain on it. The length of time varies, but using more than 3 wks typically would need a slow wean. Consult doc. Good luck.

Dr. David Geffner Dr. Geffner
Internal Medicine - Endocrinology
50 years in practice
Georgetown University School of Medicine
15

15
How could taking cortisone chronically damage the adrenal cortex?

How could taking cortisone chronically damage the adrenal cortex?

Causing hypoadrenal: The adrenal cortex makes Hydrocortisone under the influence of acth from the pituitary. Too much cortisone will suppress the pituitary so it will not stimulate the adrenal to produce its own steroid. After taking cortisone in tapering amounts the adrenal will eventually wake up.

Dr. Latoya Edwards Dr. Edwards
Family Medicine
16 years in practice
16

16
Are there any tests that check whether the adrenal medulla is functioning normally?

Are there any tests that check whether the adrenal medulla is functioning normally?

Yes: The Adrenal Medulla Secretes Adrenaline, (epinephrine, norepinephrine). Flight or Fight response. If your doctor is concerned (condition resulting in an abnormal or increase secretion). They can check hormones via blood and urine tests. The endocrinology doctor will follow this if you have abnormalities. These are not routine screening tests. They are done if there is a clinical indication (sxs)

Dr. Alok Agrawal Dr. Agrawal
Internal Medicine - Nephrology & Dialysis
30 years in practice
Andhra University, Rangaraya Medical College AKA University of Health Sciences Vijayawada
17
Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
18

18
Hi doctors, regarding to zona riticulars in adrenal cortex, how do these nuclei even produce hormons while they are pyknotic, , ? Giant thank,

Hi doctors, regarding to zona riticulars in adrenal cortex, how do these nuclei even produce hormons while they are pyknotic, , ? Giant thank,

Sloppy language: I'm glad you're reading closely. When a pathologists says "pyknotic nucleus", that cells is very dead. Some anatomists use the term more loosely for any cell with a preponderance of heterochromatin even if it's alive. We pathologists can't use any other term and wish all anatomists would say "condensed" for such nuclei instead of "pyknotic" -- it's the term other scientists use.

Dr. Thomas Knecht Dr. Knecht
Internal Medicine - Endocrinology
27 years in practice
UC San Diego School of Medicine
19

19
Are all steroid hormones produced by the adrenal cortex?

Are all steroid hormones produced by the adrenal cortex?

No: Hi. No, the adrenal cortex produces cortisol and aldosterone. Testes and ovaries produce estrogen, progesterone, and testosterone (although very different between the two different glands (and genders), of course. In addition, there's a whole fledgling field of brain steroids, some of which are made in the brain, and some of which are derived from adrenal steroids. NOW, we're havin' FUN!

Dr. Thomas Knecht Dr. Knecht
Internal Medicine - Endocrinology
27 years in practice
UC San Diego School of Medicine
20

20
I was wondering does the pituitary gland control the adrenal medulla?

I was wondering does the pituitary gland control the adrenal medulla?

No: Hi. No, the pituitary controls the part of the adrenal cortex that makes cortisol, and is a secondary regulator of the part of the cortex that makes aldosterone. Cortisol does have influential effects on the adrenal medulla, so I guess you could say there are some downstream effects from the pituitary.