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Doctor insights on: Adjuvant Melanoma Treatment

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Is adjuvant therapy(chemo) effective for non-hodgkin's lymphoma cases?

Is adjuvant therapy(chemo) effective for non-hodgkin's lymphoma cases?

Yes: Chemotherapy is the primary treatment for non hodgkins lymphoma. It's effectiveness depend on several favors like stage, type of lymphoma, and the international prognostic index. ...Read more

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Dr. Mike Bowman
961 doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin which is one of the most complex organs in the body, degenerates into cancer, with the cancerous (malignant) cells growing ...Read more


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How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

How effective is avastin (bevacizumab) as targeted therapy for the metastatic colorectal cancer?

See below: It is not a curall for colon cancer but is effective therapy to a large extent it depends onthe size and wehre it is. Almost certianly it requires more than this drug to get a cure if acure is possible. ...Read more

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Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Stage 2B IDC breast cancer, her2+/ER/PR+Neoadjuvant taxol, (paclitaxel)A/C,lumpectomy,rads, lymphovascular invasion. What does this mean for prognosis & follow up?

Prognosis fair: Stage IIb breast cancer is usually palpable at 2-5 cm. and at time of procedure to remove lesion, sentinel nodes are + suggesting axillary dissection and reason for neoadjuvant therapy. Lymphovascular invasion increases chance for recurrence. With Her2+ Herceptin (trastuzumab) with chemo should be used and PET/CAT needed to assure met foci not missed in distal organs. Carful follow up needed. ...Read more

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How effective is neoadjuvant therapy for treating colon cancer?

How effective is neoadjuvant therapy for treating colon cancer?

Partially: Chemotherapy in all of its forms is only partially helpful in improving the survival of colon cancer. When there is an effective neoadjuvant response the remaining lesion can be successfully resected. complete surgical extirpation is the needed result. As immunochemo becomes more effective then the combination with surgery will even produce better results. ...Read more

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

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What is radiation therapy treatment for colon cancer?

Energy beams: For certain types of colorectal cancer, energy beams are focused in the cancerous area. These beams are designed to kill cancer cells and decrease the chance of the tumor growing back. Depending on the situation, radiation can be used either before an operation or after an operation. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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How effective is the IFL-Bevacizumab chemotherapy regimen for treating colon cancer?

Better than chemo: Combining bevacizumab (BV)—a recombinant, humanized mAb targeting VEGF with irinotecan, fluorouracil (FU), and leucovorin (LV; IFL) has increased survival of patients with metastatic colorectal Ca compared with IFL It appears necessary to use combination therapy in treatment and has supported the concept that the use of immunochemotherapy improves results over chemo alone. ...Read more

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Is surgery ever appropriate for metastatic cancer?

Is surgery ever appropriate for metastatic cancer?

Yes: Yes. In general surgery is not useful for metastatic (spread) cancer. However in oligo (few) metastatic cancer -- especially for breast, colon, melanoma cancers patients may be rendered stage 4 ned (no evidence of disease). This may improve local control and symptoms, survival, and in a few cases even lead to cure. Removing the primary tumor (kidney) in renal cell carcinoma is helpful in met rcc. ...Read more

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How effective is the IFL chemotherapy regimen for treating colon cancer?

How effective is the IFL chemotherapy regimen for treating colon cancer?

It is an old regimen: It is one of the effective treatment regimens for metastatic colon Cancer which first appeared on the scene more than 5 years back and became popular for a while to be soon upgraded with other more effective modern regimens which also include Avastin (bevacizumab) in combination with chemotherapy. ...Read more

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Treatment for retroperitoneal scarcomas?

Treatment for retroperitoneal scarcomas?

Consult doctor: You need to consult a good oncologist for the answer to that question. ...Read more

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What are the treatment options for malignant melanoma cancer?

What are the treatment options for malignant melanoma cancer?

Many: The treatment for melanoma involves removing the primary site with a margin depending on the depth of the melanoma. In addition for high risk lesion a sentinel lymph node biopsy is performed. If these lymph node contains melanoma the remainder of the lymph nodes are removed from that basin. Treatment for distant disease can involve surgery, chemotherapy and or immunotherapy. ...Read more

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Is photodynamic therapy an effective treatment for lung cancer?

Is photodynamic therapy an effective treatment for lung cancer?

Photodynamic therapy may play a limited role in lung cancer treatment — generally complementing, rather than replacing, other forms of treatment: Photodynamic therapy may be an option for treating superficial non-small cell lung cancers that haven't spread beyond the lungs and those that are located in areas easily reached with the tools used during the treatment. Photodynamic therapy begins with the injection of a light-sensitive medication into a vein. One to three days later, the doctor shines light of a certain wavelength onto the tumor from inside the body — typically using a thin, lighted tube called a bronchoscope, which is passed through the mouth into the lungs. The light destroys the cells that have absorbed the light-sensitive medication. After photodynamic therapy, your whole body is sensitive to light. Generally you need to avoid any exposure to bright light, including the sun, for up to eight weeks after treatment. Photodynamic therapy isn't effective for cancer that has spread beyond the lung or tumors that can't be reached by the bronchoscope. ...Read more

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Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Hepatocellular carcinoma.All spleen and partial liver resection.Later,secondary systemic cancer metastasis.any targeted therapy or immunotherapy?

Yes, for both: Hepatocellular Carcinoma is commonly treated with Sorafenib which is a type of targeted therapy. This is a good choice of treatment in case you have not yet received this drug. Immunotherapy using PD-1 inhibitors has also shown some modest evidence of benefit although it is not yet FDA approved for this indication. Ask your oncologist to guide your treatment further. ...Read more

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Please describe treatment options for metastatic melanoma?

Please describe treatment options for metastatic melanoma?

SOC vs. trial: I agree with dr. Ho about standard of care (soc) options vs. Clinical trial. One online way to evaluate clinical trials based on tumor biomarkers in melanoma is here: http://www.Collabrx.Com/melanoma. ...Read more

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How effective is Xeloda (capecitabine) for metastatic breast cancer?

How effective is  Xeloda (capecitabine) for metastatic breast cancer?

It depends: As the first treatment for metastatic breast cancer, Xeloda (capecitabine) works in 40-60% of people treated. If it is the second, third or later treatment after failure of other agents, the effectiveness is much less. ...Read more

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How effective is the XELOX chemotherapy regimen for treating colon cancer?

How effective is the XELOX chemotherapy regimen for treating colon cancer?

Relatively good: According to the Journal of Clinical Oncology XELOX is a highly effective first-line treatment for metastatic colon cancer. To be more accurate (55%) of patients achieve a response, and 30% experience disease stabilization for more than 3 months following treatment. Always consult with your oncologist. ...Read more

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Can radiation treatment and chemotherapy cure esophageal cancer?

Can radiation treatment and chemotherapy cure esophageal cancer?

Sometimes: The two main types of esophageal cancer are adenocarcinoma and squamous cell carcinoma. Cure with chemotherapy and radiation alone is much more likely with squamous cell carcinoma. The exact cure rate is dependent on the stage of the cancer, but cure with just chemotherapy and radiation is rare. ...Read more

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Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Which chemo therapy is most effective for KRAS mutant metastic colon cancer ?

Same drugs as other: Same chemotherapy drugs are used for treating both types of colon cancer. The only difference is lack of benefit from EGFR inhibitors(Cetuximab and Panitumumab). Avastin (bevacizumab) also works in both types. I trust that you know there are 3 chemo drugs that are widely used(5FU or Capecitabine, Irinotecan and Oxaliplatin) ...Read more

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Is stage IV metastatic cancer treatable?

Depends: Some cancers are curable with today's chemotherapy even if they have spread extensively. Others (for example, the common lung cancers) may someday be curable when they have reached stage iv, but not today. I've just seen reports of possible cures of stage IV colon and stomach cancers; i'm hopeful. ...Read more

Dr. Travis Kidner
2,631 doctors shared insights

Melanoma (Definition)

A type of cancer that develops from pigment-containing ...Read more