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Doctor insights on: Adjuvant Chemotherapy Colon Cancer

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How effective is the IFL chemotherapy regimen for treating colon cancer?

How effective is the IFL chemotherapy regimen for treating colon cancer?

It is an old regimen: It is one of the effective treatment regimens for metastatic colon Cancer which first appeared on the scene more than 5 years back and became popular for a while to be soon upgraded with other more effective modern regimens which also include Avastin (bevacizumab) in combination with chemotherapy. ...Read more

Dr. Barry Rosen
4,224 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What is prognosis With chemotherapy for metastic colon Cancer ?

What is prognosis With chemotherapy for metastic colon
Cancer ?

So many variables: Too many variables to give you a pertinent answer. Consult your oncologist to help you with clinical decisions ...Read more

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How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI chemotherapy regimen for treating colon cancer?

Some effect: Single drug chemotherapy has failed to produce significant improvement in colorectal Ca. Combination chemo as in FOLFIRI with irinotecan has added about 5 month prolongation in survival and with immunotherapy using Avastin (bevacizumab) or Erbitux an additional 2-3 months can be observed. Chemo-Immuno with a mAb targeting the immunogenic protein appears to be giving further enhancement. ...Read more

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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

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How effective r chemotherapy uft pills in metastic colon cancer?

How effective r chemotherapy uft pills in metastic colon cancer?

Some response: meds like Xeloda have some tempoary benefit suppressing DNA function as an oral 5FU (fluorouracil). Long term responses are not seen requiring combination therapy to give an optimjum response. Eventually if cancer does show a good response, malignant stem cells will repopulate the site of the original metastasis. ...Read more

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What are the side effects of chemotherapy in treating colon cancer?

Many: Side effects are many and depend on the chemotherapy drugs used. Most of them are reversible and not permanent. Typical effects include fatigue, low blood counts, diarrhea, mouth sores, infection risks, nausea, vomiting, nerve damage, liver damage, skin rash. Rare side effects include strokes, blood clots, lung or heart damage, increasewd blood pressure, wound healing problems. ...Read more

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Ihow effective are uft chemotherapy pills for metastic colon cancer ?

Ihow effective are uft chemotherapy pills for metastic colon cancer ?

Modestly effective: Fluoropyrimidines (5-FU, Capecitabine and UFT) as a class have modest activity and one of these 3 needs to be combined with Oxaliplatin and or Irinotecan to achieve best results ,as combination chemo is far superior in efficacy than any single chemo drug ...Read more

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Can Radiotherapy be used for metastic colon cancer if chemotherapy is resistant ?

Can
Radiotherapy be used for metastic colon cancer if chemotherapy is resistant ?

Not often: Radiotherapy can be useful in certain select cases where the Cancer is localized to one or two spots only. This means 1 patient in 5 may be suitable candidate. But you need to seek consultation with a radiation oncologist before you can get a clear cut answer for your circumstances. ...Read more

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How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

How effective is the FOLFIRI-Bevacizumab chemotherapy regimen for treating colon cancer?

Moderately useful: FOLFIRI-Bev is the standard, commonly used first line chemotherapy for metastatic Colon cancer. It can add about 12 to 18 months extra to your life such that an average patient can live for 2 to 3 years(some live upto 5-6 years... depending on sites of metastases and their response to chemotherapy. You need tell us more about your history such as dates of diagnosis and treatments/results so far?? ...Read more

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Age 79, male, colon cancer Pt3n1b, surgery finished. Chemotherapy or radiotherapy recommended ? or both?

Age 79, male, colon cancer Pt3n1b, surgery finished. Chemotherapy or radiotherapy recommended ? or both?

More info: The molecular and some of the subtle microscopic features must also be considered. Then the odds with and without different modalities can be reviewed. It will be your choice. ...Read more

Dr. Eric Kaplan
923 doctors shared insights

Colon Cancer (Definition)

Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more


Dr. Oscar Novick
1 doctor shared a insight

Colon (Definition)

The colon is another term for the large intestine. This is the final portion of the digestive system, responsible for absorbing water and storing stool before evacuation. It is divided into sections described as cecum; ascending, transverse, descending and ...Read more