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Doctor insights on: Adjuvant Chemotherapy

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Dr. Janice Alexander
18 Doctors shared insights

Adjuvant Chemotherapy (Overview)

This is chemotherapy that is given to improve the chance of cure after surgery.


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What exactly is adjuvant chemotherapy?

What exactly is adjuvant chemotherapy?

Preventative: Adjuvant therapy, is treatment given following the primary, main or initial treatment. It is usually given after surgery where all detectable disease has been removed, but where there remains a statistical risk of relapse due to occult disease In contrast neoadjuvant therapy, is given before the main treatment to reduce the size of the tumor so as to facilitate more effective surgery. ...Read more

Dr. Janice Alexander
18 Doctors shared insights

Adjuvant Chemotherapy (Overview)

This is chemotherapy that is given to improve the chance of cure after surgery.


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When is it important to start adjuvant chemotherapy?

Within about 8 weeks: Most adjuvant chemotherapy trials stipulate that treatment begin within 8 weeks of surgery, thus this is generally the advice given. ...Read more

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If a breast cancer patient undergoes neo-adjuvant chemotherapy, how will she ever know her true nodal status?

Sentinel LN Biopsy: It is somewhat controversial when to perform sentinel lymph node (ln) biopsy in this setting: some advocate performing this prior to chemo, so as to determine an accurate stage; others believe that the status of the ln after chemo is most pertinent. In my practice, I will perform a needle-biopsy of any abnormal ln prior to chemo. If none are evident, I wait until after chemo. ...Read more

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Adjuvant tamoxifen or other chemotherapy for ER pr negative cancer?

Chemotherapy: Tamoxifen is only used for patients whose tumors are positive for er and/or pr. ...Read more

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What is a cycle of chemotherapy?

One to next: Chemo medicine cause lot of damage normal and malignant tissues. During development of the drug its duration effect on the tissue is studied and a fixed time is determine after which the medicine to be repeated....Risk and benefit issues. The. ...Read more

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Does chemotherapy affect eyesight?

Some: Transiently many patients will have some trouble focusing; somewhat like when ones eyes are tired. Steroids which are commonly used with chemotherapy drugs can increase cataract formation, which used to be a leading cause of poor vision, but now can almost always be fixed quite easily. ...Read more

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Is it legal to force chemotherapy?

Is it legal to force chemotherapy?

Probably no: That is more a legal than a medical question but if a patient is an adult and fully able to make decisions, the answer is likely no, both legally and ethically. ...Read more

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How severely does chemotherapy hurt?

That is a myth: Chemotherapy should not and it does not hurt!
chemotherapy is simply use of medicines to treat cancer. Why should these hurt? Yes, these medicines do have some side effects (like nausea and hair loss) but it is not any kind of pain. ...Read more

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What is chemotherapy? How does it work?

Name for drugs used: Drugs used for Cancer treatment are often called chemotherapy. These are basically chemicals, many of them synthetic, others derived from natural sources like plans and herbs. ...Read more

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Is the chemotherapy a risky thing to do?

Yes: Chemotherapy has many potential risks. The potential adverse events and dose limiting toxicities should be discussed the your cancer physician and team. The important concept is understanding the "risk/benefit ratio". That is, what potential benefit is worth the risks? Also, what alternatives are available? ...Read more

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If you have chemotherapy can you have kids?

If you have chemotherapy can you have kids?

Yes: This is a great question! chemotherapy can damage your eggs or sperm, so it's vital that you talk about your desire to have children before starting chemotherapy! Men can bank sperm before chemotherapy and women can bank eggs/embryos. Many types of chemotherapy can make you infertile depending on your age, but you can safely have children later if you've planned ahead and stored your "stuff"! ...Read more

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What risks are associated with chemotherapy?

What risks are associated with chemotherapy?

There are a few: Chemotherapy has side effects but they can be controlled with counter drugs. Side effects may come in the form of nausea, vomiting, hair loss, low blood counts which can lead to infections. So a close monitoring is required and antidotes to prevent these side effects are used as needed. ...Read more

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Is it a sure thing that chemotherapy will work?

Is it a sure thing that chemotherapy will work?

No: The chance of chemotherapy working depends on a number of factors including -- tumor type, stage, prognostic factors as well as host (patient) characteristics such as age, genetics, etc. ...Read more

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What are common chemicals used in chemotherapy?

Lots of them!: cancer chemotherapy has a very large number of chemicals/drugs that are used...at least over 100 are commonly used drugs at present, many older ones have been discarded as better ones came along.
Why do you ask this question? ...Read more

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What is topical chemotherapy? And when is it used?

Topical chemotherapy: Chemotherapy refers to the treatment of conditions with drugs, and often is applied to the use of anti-cancer agents (but may also be applied to others). Topical means that it is applied directly to the lesion in question and is not taken systemically (by mouth or injection) and meant to get the lesion through the blood stream. Hope this is clear. Good luck. ...Read more

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What is the most effective ingredient in modern chemotherapy?

Depends: It will depend on the type of cancer & the biology of cancer. Different cancer requires different approach and treatment. However I think the answer is a targeted therapy specifically targeted to the mutated receptors in cancer cells.
The best story of effective therapy of cancer in modern chemotherapy era is the story of Gleevec (imatinib) for cml. ...Read more

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What was chemotherapy like in the early 1980s? How has it changed?

Chemotherapy 1980: In my opinion. The most important development was the discovery and the use of antiemetics. The medications that prevent nausea and vomiting. This discovery made chemo. Bearable and many patients were able to tolerate it. ADD to this the discovery and use of growth hormones like neupogen, neulasta (pegfilgrastim) and procrit that helped shortening of the periods on neutropenia and we are able to give r the doses ...Read more

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I'm curious what occurs during a typical treament of chemotherapy?

Kept in positon: Most chemotherapeutic agents are delivered intravenously while a few can be given orally. With IV therapy which is given over several hrs the patient is kept in a lounge chair. Because of toxicity to the veins when given iv, a port is usually placed in the subclavian vein and placed under the skin where the IV line can easily be introduced. ...Read more

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Could you tell me what is the maxium a person could go for chemotherapy in a week?

Could you tell me what is the maxium a person could go for chemotherapy in a week?

Depends: Some protocols give chemo daily x 5 days, others x2 or x3. Yet others administer it as a continuous drip with a portable pump for weeks at a time. It depends on the drug and the program. ...Read more

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Will chemotherapy make you sterile?

Maybe: Chemo can definitely reduce fertility. I discuss fertility with all patients of childbearing age, and offer sperm banking to men, and referral to a fertility expert for egg harvest for women.

Menstruation after chemo is generally a marker for fertility.

Chemo can induce damage to the genes in sperm and eggs, and patients shouldn't conceive during chemo due to risk of birth defects. ...Read more

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Is chemotherapy actually very toxic?

Is chemotherapy actually very toxic?

Possible: Chemotherapy is a broad term for a large number of drugs used alone or in combination. Also the doses vary depending upon the disease. The are also variations in individual's susceptibility. There are also a large number of drugs used to combat side effects.
I can only say that it can be anything from very toxic to mild depending on the situation. ...Read more

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How can the chemotherapy affect my dad?

Good question: But impossible to answer here. Depends on what cancer he has, what chemo he gets, how healthy he is, and many other factors that we do not know. Even so, people react differently to drugs so there is always a degree of uncertainty. You need to go over this with his oncologist before he gets the chemo. ...Read more

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Is hyperkalemia related to chemotherapy?

Is hyperkalemia related to chemotherapy?

Not necessarily: The start of chemo may cause hyperkalemia in certain cancers (leukemias, lymphoma).
Certain chemo can affect the kidneys causing hyperkalemia. But chemo is not always related to hyperkalemia. ...Read more

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Stoping chemotherapy is it bad for the patient?

Tough question!: I am assuming the question is about you, but that may not be the case. I wonder if you are thinking of stopping chemotherapy because of side effects of medications. If so, ask your oncologist - there may be other chemotherapy medications that will work as well and give you less side effects. I always wonder about depression, too. Chemo - and cancer - can be a lot to handle. Get support for this! ...Read more

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Could chemotherapy rid your body of paarasites?

Possibly?: If you are referring to cancer chemotherapies, it is theoretically possible that a given chemotherapy drug could be toxic to a parasite. A quick search of the literature did turn up a class of cancer chemotherapeutics called kinase inhibitors that affects certain signaling pathways in human cells that certain parasites (malaria) require for reproduction in the host. ...Read more

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Is chemotherapy safe for treating linear morphea?

Is chemotherapy safe for treating linear morphea?

LINEAR MORPHEA: ARE YOU TRYING TO KILL A FLY WITH A GUN?
MORPHEA, ALSO KNOWN AS SCLERODERMA, IS A CONNECTIVE DISORDER OF THE SKIN.
PLEASE SEE A DERMATOLOGIST. ...Read more

Dr. Devon Webster
972 Doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more