Doctor insights on:
Adh Overdose Signs
Seek Med help if OD: Dear htreference, An OD of ADH can result in excess water retention that can cause electrolyte abnormalities, especially low sodium (hyponatremia) that can be dangerous. Symptoms of too much ADH can include, but not limited to headache, drowsiness, weakness, pale skin, nausea, and stomach pain. A good resource to consider for questions-https://www.poisonhelp.hrsa.gov/the-poison-help-line/ ...Read more
ADH (vasopressin): Adderall (dextroamphetamine and racemic amphetamine) 10 (4 reports): more effective for people 40-49 years old Adderall (dextroamphetamine and racemic amphetamine) 30 (3 reports): more effective for females 20-29 years old Adderall (dextroamphetamine and racemic amphetamine) 5 (4 reports): more effective for males 20-29 years old concerta (4 reports): more effective for females 10-19 years old vyvanse (10 reports): more effective for females 20-29 years old. ...Read more
During fluid deprivation test, the ADH (vasopressin) level dropped down to 1/3 of pre test level and below reference values. Is that a sign of diabetes insipidus?
Not necessarily: The most important thing to be following in a water deprivation test is the urine and serum osmolality. If the serum osmolality rises above normal, but the urine osmolality does not rise significantly, you have diabetes insipidus. Measuring ADH (vasopressin) levels can be unreliable. ...Read more
Low sodium: ADH (vasopressin) is anti-diuretic hormone which causes your body to retain free water. When you have too much of it, your body retains too much free water and "dilutes" out the sodium content in your blood which will cause the level to drop. Low sodium in the blood can be very detrimental to your health. ...Read moreSee 1 more doctor answer
As a protein: Dissolved in the blood.Get a more detailed answer ›
Not a clear answer: From amini and schmidt, who looked at ADH (vasopressin) secretion after spine surgery, "the mechanism by which CNS disorders cause SIADH (vasopressin) is not well understood. Most authors hypothesize that injury to the CNS disrupts or alters the osmoregulation of ADH (vasopressin) release by the neurohypophysis, stimulating inappropriate release of adh (vasopressin).". ...Read more
Breast cancer marker: ADH (vasopressin) is an abnormal proliferation of breast duct cells that is benign but is associated with present or future breast cancer. ADH (vasopressin) is suspected on mammograms with microcalcifications and is diagnosed on needle biopsy and usually requires surgical excision. About 30% of excisions for ADH (vasopressin) will show cancer. For the other 70% of women the risk of developing breast cancer over the next 8 years is 3.7%. ...Read moreSee 1 more doctor answer
ADH (vasopressin) & Oxytocin: Both are produced in hypothalamus and stored in the posterior pituitary gland. ...Read more
Pituitary: Hi. ADH (vasopressin) & oxytocin are made in neurons in the hypothalamus and travel down the axons in the pituitary stalk to the posterior pituitary where they are stored until they're released. They're referred to as "posterior pituitary hormones", but they're made in the hypothalamus and only stored and released from the posterior pituitary. ...Read more
Kidney and water: Hi. ADH (vasopressin) prevents the kidney from putting water out in the urine (a graded dose-response). If solutes in the blood are becoming too high a concentration, ADH (vasopressin) is secreted and makes the kidney put water from the kidney filtrate back into the blood, which dilutes out the solutes and brings down the osmolarity. Falling osmolarity suppresses ADH (vasopressin) secretion. The waltz goes on. ...Read more
Snake oil: It is one of many unregulated, un tested, and non-sensical agents sold for the purpose of weight loss. Its claim is adrenal regulation, but there are no ingredients in it to do that; if there were, it would be only used for specific syndromes managed under the care of an endocrinologist. Ask your doctor about a diet and exercise program. ...Read moreSee 1 more doctor answer
Nocturia: Hi. How many times do you get up to pee on an average night? Diabetes insipidus (poor ADH (vasopressin) production or function) is a very uncommon cause of nocturia. The most common is drinking a lot in the evening. Diabetes mellitus is also a common cause of nocturia. Congestive heart failure or any cause of lower extremity edema where the kidneys still work will cause nocturia. ...Read more
What hormone inhibits the secretion of adh (vasopressin)? And what situations override the release of this inhibiting hormone?
ADH (vasopressin) secretion: ADH (vasopressin) is mostly controlled by plasma osmolality and plasma volume. Diabetes insipidus occurs when ADH (vasopressin) is not secreted (head trauma, pituitary tumor) or when the kidney does not respond to it (nephrogenic di). Ethanol inhibits adh, (vasopressin) as does atrial naturetic protein, but these are lesser influences than osmolality and volume. ...Read more
In what circumstances will aldosterone be secreted over ADH (vasopressin) and vice versa. Are they both secreted in response to low BP? What about low plasma osm?
Good questions!: Aldosterone release is regulated by renin. I believe hypotension (or rather long-standing hypoperfusion) may be a trigger, especially in secondary aldosteronism (due to CHF, for example) ADH (vasopressin), (vasopressin) on the other hand, is triggered by hyperosmolarity, rather than hypotension. Low osmolarity will, of course, suppress ADH (vasopressin). ...Read more
Many causes: Poor ADH (vasopressin) production is an extremely rare cause for frequent urination at night. One of the most common causes is fluid retention during the day. If you have varicose veins or other causes for swelling of the legs, once you lie down at night, the fluid comes out of the legs and into your bladder, making you urinate more. If you drink a lot in the evening, you will urinate more at night. ...Read more
Morning hp 120/80 but goes up to 185/85 just after taking bystolic (nebivolol) or isosorbide and stays for an hour. On 5 mg pred/arb in pm/no issues. Adh issue?
No, isosorbide: B"sd Amazing occurence. Bystolic (nebivolol) is a balanced blocker with both beta and some alpha blocking - not likely the cause. Isosorbide is a vasodialator and in fact has been reported as a cause of paradoxical hypertension. See: http://www.ncbi.nlm.nih.gov/pubmed/9752888 Would consult with your cardiologist, as to relevance of this possibility in your case. ...Read more
It's possible: It's possible to have both a bipolar disorder and adhd. To make such a determination a professional would need to carefully evaluate your history and symptoms. It is somewhat challenging for a professional to make this determination due to the fact that there are overlapping symptoms in the two disorders. You are you, and you can get an individualized treatment plan regardless of diagnoses. ...Read more
Yes and now : When you body is dehydrated, your body holds on to both sodium (salt) and water. The antiduiuretic hormone helps you hold on to water by decreasing the amount of urine that you produce. However, another hormone (aldosterone) is responsible for the preservation of sodium by limiting losses through your kidney. ...Read more
Signal-response.: Adh, or vasopressin, is a hormone released by the posterior pituitary gland when the body wishes to conserve water. Aquaporin 2 (aqp2) channels in the kidney are activated by adh, which reabsorb water back into the bloodstream, concentrating and decreasing the volume of urine. Mutations in aqp2 can lead to diabetes insipidus, where large volumes of urine are released. ...Read more
Signal/response.: Adh, or vasopressin, is a hormone released by the posterior pituitary gland when the body wishes to conserve water. Aquaporin 2 (aqp2) channels in the kidney are activated by adh, which reabsorb water back into the bloodstream, concentrating and decreasing the volume of urine. Mutations in aqp2 can lead to diabetes insipidus, where large volumes of urine are released. ...Read more
If the posterior pituitary only stores the ADH (vasopressin) the hypothalamus makes, how come ADH (vasopressin) doesn't go into the bloodstream when the hypothalamus is in tact?
Released by need: I'm not sure I understand what you mean. ADH (vasopressin) in fact, is secreted or released into the bloodstream from the post. pituitary. It is released according to demand and not before. So if you're asking why doesn't it "pour" out into the bloodstream then, that's the reason. There is a gating effect whereby NEED of the body (having to do mainly with sodium concentrations) signals the gate to open&close ...Read more
ADH (vasopressin): My apologies but I have spent some time on line and could not find the answer to your interesting question. You might go the Medical University's library and see what you can find. The librarian will help you. If you do find out please try and let me know. ...Read more