Doctor insights on:
Acute Transverse Myelitis
ADEM: Acute disseminated encephalomyelitis is a rare autoimmune disease affecting the brain & spinal cord, damaging the myelin & destroying the white matter. Symptoms are similar to Multiple sclerosis. It usually follows viral infection or vaccination. Symptoms start with fever, headaches, drowsiness, seizures. ...Read more
Definition of inflammation of the spinal cord could be a very long list of causes. But in short inflammation is some sort of irritation to the cord that can be caused by infection, injection of foreign materials or even bleeding into the area around the cord. It is a very general terminology and in a diagnostic workup would have to be more focused on what might the ...Read more
Variable: Depends on the cause. Ms-related tm can resolve completely symptomatically (although some neuronal damage persists). Things like devic's disease, spinal vein obstruction, guillain barre are more "iffy". A diagnosis of cause gives your neurologist a much better opportunity to provide you with a prognosis. ...Read more
Childhood illness: Occurs in childhood, and typically monophasic, but could be confused with MS in some cases. Typically follows viral infection or vaccination and can result in diffuse encephalopathy. Classic MRI findings of large white matter lesions which light up with contrast help confirm. Typically does NOT recur. ...Read more
Can autoimmune encephalitis triggered by past infection be insidious unlike acute disseminated encephalomyelitis?
Rasmussen syndrome: There are several others that are even less common ...Read more
Usually yes: Although very small lesions may on occasion be missed, an area of transverse myelitis is usually very easy to identify. Might be tough to see in the first few hours of development, but the area of inflammation becomes very definite as the process proceeds. Spinal fluid analysis helps in explaining causation. ...Read more
A friend had chronic demyelinating polyneuropathy (cidp), then got chronic lymphocytic leukemia 2 years later. Is cidp paraneoplastic syndrome sometimes?
Not likely: Chronic inflammatory demyelinating polyradiculopathy (cidp) is almost always an autoimmune condition incited by some antecedent infection--c. Jejuni, ebv, cmv, or another infection. Antibodies produced against the virus/ bacteria/ pathogen cross-react with the myelin sheath on the nerve roots, first causing guillain-barre (aidp), then later cidp. It's exceedingly rare that cancer could cause this. ...Read moreSee 2 more doctor answers
Brain MRI results: differential includes nonspecific demyelinating process such as MS vasculitis and infectious etilogies. What does this mean?
Meaning of MRI: Differential- this refers to the list of possible diagnoses for the person. The radiologist is not exactly sure what the imaging diagnosis is but what they are saying is that it looks like is ms or ms like things. Ms vasculitis (swelling of the arteries seen in ms). The other thing he/she thinks is possible are infectious etiologies (causes: such as bacterial or viral infection. ...Read moreSee 2 more doctor answers
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