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Doctor insights on: Acute Thrombocytopenic Purpura

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Difference between idiopathic thrombocytopenia purpura and thrombotic thrombocytopenia purpura?

Difference between idiopathic thrombocytopenia purpura and thrombotic thrombocytopenia purpura?

The are completely: Different. Itp is the autoimmune destruction of platelets and is managed with immunosuppression - the first line is usually prednisone. Ttp is the microvascular consumption of platelets (small clots). This can be associated with anemia, renal failure, ha and fever. It is a medical emergency and is managed with plasma exchange. ...Read more

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Non Blanching Red Or Purple Spots (Definition)

Non blanching red or purple spots can describe purpura, which is bleeding beneath the skin that does not blanch with pressure. It can be caused by platelet disorders, coagulation disordes, vascular ...Read more


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What's thrombocytopenic purpura?

What's thrombocytopenic purpura?

There are 2 types: Of thrombocytopenic purpura. The idiopathic type is low platelets due to immune destruction (itp). The consumption of platelets be formation of miniclots in the small vessels is called thrombotic (ttp). ...Read more

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Can autoimmune cause henoch schonlein purpura?

Can autoimmune cause henoch schonlein purpura?

Yes, it is autommune: Vasculitis below the waste, possible renal involvement. It an autoimmune disease that can be bad. Most patients will have a short lived course. ...Read more

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What is idiopathic thrombocytopenia purpura?

What is idiopathic thrombocytopenia purpura?

Autoimmune disease: Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. Persons with the disease have too few platelets in the blood. Check this site: http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0001562/. ...Read more

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Itp - idiopathic thrombocytopenic purpura, what is this?

Itp - idiopathic thrombocytopenic purpura, what is this?

ITP is just what...: It sounds like. It is characterized by bleeding, bruising (purpura) and petechiae that develop because of a low PLT count (aka thrombocytopenia), and where the specific trigger for thrombocytopenia is not known (idiopathic). We do know that in itp, the pt makes antibodies to auto-antigens found on the PLT surface (often pla-1) which mark them for destruction. This makes the PLT count low. ...Read more

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Henoch schonlein purpura symptoms?

Henoch schonlein purpura symptoms?

May start as rash: The rash may start above the feet and progress over the knees. It does not blanche if you press on it and release it, because the little red spots are bleeds, called petechiae. Next the feet swell and may develop pitting edema. You now need an immunologist assessment and therapy with steroids to prevent kidney involvement and arrest progression of this autoimmune disease.Serum IGA may be high. ...Read more

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Brittany Chan Dr. Chan
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What is thrombotic thrombocytopenic purpura (ttp)?

Brittany Chan Dr. Chan
5 doctors agreed:

Platelet disorder.: Ttp is a blood disorder in which platelets form small clots. Formation of these clots uses up so many platelets that platelet count becomes low. The clots can get stuck in small blood vessels and cause damage to red blood cells, causing anemia. Other symptoms of ttp include fever, kidney failure, & neurologic problems. The biological cause of ttp is still uncertain. ...Read more

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Idiopathic thrombocytopenic purpura, wha tis this?

Idiopathic thrombocytopenic purpura, wha tis this?

Platelets destroyed: ITP is a bruising disease where your platelets are destroyed for an unknown reason and it causes you to bleed. This oversimplified but a complicated answer won't fit in 400 characters. ...Read more

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What is the disease ?Thrombotic thrombocytopenia purpura?

What is the disease ?Thrombotic thrombocytopenia purpura?

Abnormal platelet: Function due to deficiency of a metaloproteinase. Deficiency, usually acquired, of an enzyme that breaks down large multimers of von willebrand factor causes overactivation of platelets leading to intravascular microthrombi that affect the functions of the kidneys, brain, lungs and other organs. It can be treated by transfusing normal donor plasma. ...Read more

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
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Can you die from thrombotic thrombocytopenia purpura?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Can you die from thrombotic thrombocytopenia purpura?

YES: Unfortunately, yes. People can die from ttp. They can develop seizure, coma, renal failure, cardiac hemmorhage/bleeding, sudden cardiac arrest, myocardial infarction etc. Need to get treatment as soon as possible. ...Read more

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What is an idiopathic thrombocytopenic purpura ?

What is an idiopathic thrombocytopenic purpura ?

Low platelets: Idiopathic thrombocytopenic purpura (itp) is an immune-mediated problem that leads to a very low platelet count. This leads to a very high risk of bleeding. It is generally treated with immune suppressing medications such as steroids. ...Read more

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Most common symptoms of thrombotic thrombocytopenia purpura?

Range of symptoms: Ttp can involve many different organs. One can have renal dysfunction, fever, altered mental status, low platelet counts and hemolytic anemia. These signs can lead to symptoms of bleeding, bruising, petechiae, confusion, anemia, fatigue, and possible jaundice among other things. ...Read more

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How common is henoch schonlein purpura?

Commonly uncommon: Quoted figures are between 6 and 22 per 100,000 children. So if you estimate 1 in 10,000, most pediatricians will see a few cases in their careers, and most people (friends, neighbors and family) will never have heard of it. Consider it a common disease that is uncommonly seen. ...Read more

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Can idiopathic thrombocytopenic purpura cause fertility issues?

Can idiopathic thrombocytopenic purpura cause fertility issues?

Yes: Idiopathic Thrombocytopenia Purpera is an autoimmune mediate destruction of platelets due to anti-platelet antibodies. This may predispose you to disruption of successful pregnancy as result of interruption of the vascular supply to the placenta, which prevents successful pregnancy. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Does itp (immune thrombocytopenic purpura) weaken the immune system?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:

No: Itp does not supress immune system. Itp is treated commonly with immunesupressive agents such as corticosteroids, rituxan- and thse treatment would supresse immune system. ...Read more

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Neonatal alloimune thrombocytopenia treatment?

Neonatal alloimune thrombocytopenia treatment?

Platelet transfusion: If the fetus has an antigen on platelets that the mother lacks, she may make antibodies that destroy the fetal platelets. Infusing platelets that lack the antigen is the treatment. Platelets can be infused into the fetus in utero, if needed, . ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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What is the treatment for thrombotic thrombocytopenic purpura?

What is the treatment for  thrombotic thrombocytopenic purpura?

Plasmapheresis: Ttp can be caused by a medicine, it must be stopped. The treatment can be plasmapheresis, ie blood cleansing and also treated with intravebous gammaglobulin, it still hs a highmnortality. ...Read more

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Is thre any treatment for idiopathic thrombocytopenic purpura itp in pregnancy?

Yes.: Itp in pregnancy is treatable. It does depend on what medications have worked in the past. If the itp has never been treated, there are several options. Steroids are often used in pregnancy. The itp, even if treated in the mom, can cause low platelets in the newborn. This may be of more concern if mom has had her spleen removed or if othersib, inge have had trouble with low platelets at birth. ...Read more

Purpura (Definition)

Purpura are non blanching red or purple spots caused by bleeding beneath the skin. The spots do not blanch with pressure. They can be caused by platelet disorders, coagulation disordes, vascular ...Read more