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Doctor insights on: Acute Renal Failure Pathophysiology

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What causes acute kidney failure?

What causes acute kidney failure?

Toxic insults: Low blood pressure, interruption of blood flow, obstruction of urine flow, drug allergies, toxic drugs, autoimmune disease, heart failure, chronic liver disease, sepsis, underlying problems such as diabetes and myeloma increase the chance for renal failure. There are many causes, most are evident upon inspection of the patient, this requires expert attention and action to reverse the process. ...Read more

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Dr. Jack Rubin
92 doctors shared insights

Acute Renal Failure (Definition)

Acute renal failure, also known as acute kidney failure, occurs when your body is unable to clear out the products of metabolism that are normally filtered and excreted by your kidneys. Accute renal failure can be caused by the obstruction of urine flow, infection, severe metabolic ...Read more


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What is acute renal failure?

What is acute renal failure?

Acute renal failure: This is when your kidneys abruptly stop working or greatly slow down in their ability to clean the blood of things that you body does not need..Many substances normally removed by the kidney are potentially harmful if they build up in your blood. Examples of this are too much acid, potentially harmful byproducts of drugs you are taking, and the end products of protein metabolism. ...Read more

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What is chronic renal failure?

What is chronic renal failure?

Lab testing: A creatinine clearance number of less the 10 generally determines renal failure. This number is calculated by your age, weight and sex. Not all people with ckd need dialysis right away. This is determined by symptoms associated with renal failuire like high potassium, volume overload(edema and difficulty breathing), itching, poor appetite, other "uremic" symptoms. ...Read more

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Could pyelonephritis cause acute kidney failure?

Could pyelonephritis cause acute kidney failure?

Yes: If your kidneys are already not working correctly or the infection goes for a long time untreated or both you can have acute renal failure. If you are concerned or believe you have problems with your kidneys, please see your doctor asap and have this investigated. ...Read more

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Hi, is the metabolic acidosis in chronic renal failure fatal ?

Acidosis: The simple answer is yes. However, the amount of acid has to be very high for that to happen. High amounts of acid in the blood interfere with many, if not all, biologic processes in the human body such as the effect of Insulin lowering blood sugar, the normal metabolism of proteins and fats that are essential for life, and even normal heart beat, just to name a few. ...Read more

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Does renal cell carcinoma lead to chronic renal failure?

Does renal cell carcinoma lead to chronic renal failure?

Not necessarily: Only if both the kidneys have to be removed if cancer on both sides. If only one kidney or a part of kidney only is removed and the remaining kidney is healthy dialysis is not required. ...Read more

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What is the difference between acute renal failure and acute renal insufficiency?

Acute renal failure: Failure means kidneys stopped completely. Insufficiency not completely gone but not normal. ...Read more

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Does acute renal failure reverse itself?

Does acute renal failure reverse itself?

With treatment : Generally yes, but intervention must occur as early as possible. It does depend on the severity. ...Read more

Dr. Jay Park Dr. Park
2 doctors agreed:
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What is metabolic acidosis in chronic renal failure from?

Dr. Jay Park Dr. Park
2 doctors agreed:
What is metabolic acidosis in chronic renal failure from?

Unable to remove: Metabolic acidosis is a constituent of renal failure, arising mainly from the inability of kidney to remove excess acids in blood. ...Read more

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Can heart failure cause renal failure?

Can heart failure cause renal failure?

Yes: Heart failure can cause decreased blood flow to the kidneys, causing decreased renal function. Renal failure can also exacerbate heart failure by increasing blood pressure and decreasing salt elimation, resulting in intravascular volume overload, resulting in increased pressure in the chambers of the left side of the heart. ...Read more

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What is the difference between acute renal failure and end-stage renal failure?

Renal failure: Acute renal failure: seen in a healthy person who develops an illness (e.g. hemolytic uremic syndrome [in children] or septic shock and multiple organ dysfunction) that leads to renal failure. Often it resolves. End-stage renal disease implies that the problem has been there for weeks/months, is not going to resolve and the person may need kidney transplant ...Read more

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Chronic glomerulonephritis pathophysiology?

Chronic glomerulonephritis pathophysiology?

Complex: Reduction in nephron mass from an injury reduces the gfr. This reduction causes hypertrophy & hyperfiltration of the remaining nephrons & to intraglomerular hypertension. These changes occur to increase the GFR of the remaining nephrons, thus minimizing the functional consequences of nephron loss. The changes are ultimately detrimental because they lead to glomerulosclerosis & further nephron loss. ...Read more

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Can haemodialysis correct metabolic acidosis in renal failure patient?

Can haemodialysis correct metabolic acidosis in renal failure patient?

Renal Replacement Th: Dialysis is one of the treatments for metabolic acidosis. Depending on the cause as well as the other medical problems and type of the acidosis, correcting the inciting problem is the first step dialysis may or may not be needed. ...Read more

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Kidney failure symptoms?

Kidney failure symptoms?

Uremia: If you have renal failure and is unable to excrete toxins and excess electrolytes/water from your body, you are likely to have symptoms and signs of uremia. They include nausea/vomiting, loss of appetite, inability to concentrate, diffuse itching, and lethargy in addition to having fluid retention. ...Read more

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Congestive heart failure, kidney failure and staph?

Congestive heart failure, kidney failure and staph?

CHF, kidney, staph: Patients with a staph infection can have an endocarditis, which affects the heart valves. Once it is on a valve, septic emboli can be sent to other places, the brain, retina, bone or kidney. Those emboli to the kidney can cause renal failure. A damaged heart valve can also cause chf. I would imagine the person you are talking about is in the hospital, perhaps you should speak to her doctor. ...Read more

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Why does chronic glomerulonephritis lead to renal failure?

Complex: Chronic immune mediated inflammation of the glomeruli (filtering units), does them in over time and causes loss of ability to clear the daily toxin and water load. ...Read more

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How are acute and chronic kidney failure different?

How are acute and chronic kidney failure different?

Acute: recent: In gral. "acute" means of "recent" origen, and "chronic" means "old" or less recent. Some classifications use 6 months for "subacute". Chronic renal failure is insidious and depends upon the cause and how fast it gets worst. Acute renal failure usually is caused by low fluid volume in the body either dehydration or bleeding or it may be caused by toxins (poison, medications , dye contrast). ...Read more

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How are congestive heart failure and chronic heart failure different?

How are congestive heart failure and chronic heart failure different?

Volume status: Congestive identifies somebodey with volume overload. Heart failure may be present without having overt "congestion" currently. ...Read more

Dr. Tarek Naguib
622 doctors shared insights

Kidney Failure (Definition)

A condition in which the kidneys lose the ability to remove ...Read more


Dr. Fred McCurdy
108 doctors shared insights

Acute Kidney Failure (Definition)

An abrupt ...Read more