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Doctor insights on: Acute Myeloid Leukimia

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What's acute myeloid leukemia?

What's acute myeloid leukemia?

See links: For a nice overview of aml, see the following pages at the national cancer institute. For adult: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient for pediatric: http://www.Cancer.Gov/cancertopics/pdq/treatment/childaml/patient. ...Read more

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Dr. Liawaty Ho
1,150 doctors shared insights

Leukemia (Definition)

A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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Aml acute myeloid leukemia is what?

Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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Is acute myeloid leukemia harmful?

Yes! AML can kill.: Acute myeloid leukemia can be very aggressive. Generally it is treated at major clinical centers with a lot of expertise in leukemia especially at first. AML is seen in both children and adults. I would recommend that if either you or a family member is diagnosed with this to seek out a center of excellence. ...Read more

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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What is acute myeloid leukemia is?

Marrow malignancy: AML is a bone marrow malignancy characterized by uncontrolled growth of leukemic cells in the bone marrow. It leads to very high white blood cell counts, anemia and thrombocytopenia (low platelets). It is rapidly fatal without prompt diagnosis and treatment. It can be cured in up to about 40% of people. ...Read more

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What is acute myeloid leukemia (aml)?

What is acute myeloid leukemia (aml)?

Bone marrow cancer: White blood cells live and grow in the bone marrow and enter the blood stream where they travel throughout the body to fight infection. If these cells become cancerous, they grow out of control choking out the normal blood cells in the bone marrow and leaving the person vulnerable to infection, bleeding and anemia because there are not enough normal cells. All ages get AML but usually younger. ...Read more

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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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What percent of leukemias does acute myeloid leukemia represent?

AML: AML is the most common acute leukemia in adults and accounts for approximately 80 % of cases in this group. In us and europe, the incidence has been stable at 3 to 5 cases per 100, 000 population. In contrast, AML accounts for less than 10 % of acute leukemias in children less than 10 years of age. ...Read more

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Acute myeloid leukemia m2 relapse, what to do?

Acute myeloid leukemia m2 relapse, what to do?

See below...: Relapses of various types of leukemia including AML are still treatable. Consultation with an oncologist to discuss treatment options including chemotherapy and possibly bone marrow or stem cell transplantation is of paramount importance in managing the disease. ...Read more

Dr. Agos Luca Dr. Luca
6 doctors agreed:
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What is acute lymphoblastic leukemia (all)?

Dr. Agos Luca Dr. Luca
6 doctors agreed:

Blood cancer: All is a form of leukemia which in turn is a form of cancer, more specifically blood and bone marrow cancer. The word "acute" means it progresses faster, as opposed to chronic cases that usually have a slower progression. The word "lymphoblastic" means immature lymphoid and describes the type of malignant cell involved in this leukemia, as opposed to other types of cells, for example myeloid. ...Read more

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What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

Types of cells: White blood cells are different with different mechanisms to pretect body from infections. Acute myeloid leukemia arise from a type of white cells called myeloid series or neutophils, cut lymphoblastic leukemiaa arise from lymph type of white cells. These two types of leukemia have different treatments and the outcome or expectations are very different, none is better than the other in general. ...Read more

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What is chronic myelogenous leukemia?

What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

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What is acute leukemia?

What is acute leukemia?

It is a disease: Acute leukemia is a blood disorder where white cells are not formed normally. It has excellent treatment available now. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

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Dangers of chronic myelogenous leukemia?

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. ...Read more

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Symptomatology level of what would be the difference between acute myeloid leukemia and acute lymphoid leukemia?

Symptomatology level of what would be the difference between acute myeloid leukemia and acute lymphoid leukemia?

AML vs. ALL: The symptoms of AML and all can be quite similar since both cause anemia (low red cells) and low platelets (which causes bruising and bleeding). In addition, they both cause an increased risk of various infections. AML is more likely to cause swollen gums and lumps on the skin. All is more likely to cause neurological symptoms since it can sometimes get into the brain or spinal fluid. ...Read more

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

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Successful treatment of a child with t/myeloid acute bilineal leukemia associated with tlx3/bcl11b fusion and 9q deletion?

Yes.: This is uncommon, but certainly treatable. The treatments are not straightforward, but intense treatment is typically required. There is a report recently of successful treatment with bone marrow transplant. ...Read more

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What's acute myeloid leukemia?

See links: For a nice overview of aml, see the following pages at the national cancer institute. For adult: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient for pediatric: http://www.Cancer.Gov/cancertopics/pdq/treatment/childaml/patient. ...Read more

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What is acute myeloid leukemia is?

Marrow malignancy: AML is a bone marrow malignancy characterized by uncontrolled growth of leukemic cells in the bone marrow. It leads to very high white blood cell counts, anemia and thrombocytopenia (low platelets). It is rapidly fatal without prompt diagnosis and treatment. It can be cured in up to about 40% of people. ...Read more

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Is acute myeloid leukemia harmful?

Yes! AML can kill.: Acute myeloid leukemia can be very aggressive. Generally it is treated at major clinical centers with a lot of expertise in leukemia especially at first. AML is seen in both children and adults. I would recommend that if either you or a family member is diagnosed with this to seek out a center of excellence. ...Read more

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How do you cure acute myeloid leukemia?

How do you cure acute myeloid leukemia?

Chemo/transplant: Not all acute myeloid leukemia can be cured. Some acute myeloid leukemia with good genetic or molecular profile can be well treated or even cured by current standard intense chemotherapy and stem cell transplantation. ...Read more

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I have acute myeloid leukemia, what to do?

See below...: Once a diagnosis of leukemia is made, a referral to a hematologist/oncologist is necessary. The oncologist will decide what the best treatment plan is and how to manage the condition. Immediate consultation with a hematologist/oncologist is of paramount importance for a favorable outcome. ...Read more

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What are the symptoms of acute myeloid leukemia?

Fatigue, fever etc: Acute myeloid leukemia starts from bone marrow, where normal blood cells were made. Leukemia cells will decrease the abilities of bone marrow to make normal blood cells such red blood cells (delivery oxygen); white blood cells (fight for infection), and platelets (stop bleeding). Therefore, the symptoms can be fatigue, fever, bruising or bleeding, bone pain, swollen glands, and weight loss. ...Read more

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How long does it take for acute myeloid leukemia to develop?

It is really: Hard to tell accurately but it is pretty fast . As the name indicate , people with the condition are diagnosed when they develop one of the catastrophic symptoms. In general the development is pretty acute and progression is fast unless treated aggressively ...Read more

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What percent of leukemias does acute myeloid leukemia represent?

AML: AML is the most common acute leukemia in adults and accounts for approximately 80 % of cases in this group. In us and europe, the incidence has been stable at 3 to 5 cases per 100, 000 population. In contrast, AML accounts for less than 10 % of acute leukemias in children less than 10 years of age. ...Read more

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What is the definition or description of: acute myeloid leukemia?

A cancer of the Whit: A leukemia is type of blood cancer arising from the white cells.Acute myeloid leukemia also called AML is a serious type of cancer which has good chemotherapy based treatments available but they are best done by a leukemia specialist at a major cancer center. ...Read more

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What are mv4-11 cells of acute myeloid leukemia? What does this mean?

MV-4-11: ...this is the name of a leukemia cell line used by cancer researchers. They originally came from a 10 year old boy with acute leukemia and they have the convenient property of being able to grow endlessly in a lab cell culture dish. Cancer researchers might use them for various purposes, such as testing new drugs, before trying them in people. ...Read more

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Are certain groups more susceptible to acute myeloid leukemia? Do some groups experience this disease differently than others?

Are certain groups more susceptible to acute myeloid leukemia? Do some groups experience this disease differently than others?

Yes.: Down syndrome and various bone marrow failur syndromes can increase the risk for aml. Also chronic leukemia and melody spastic syndrome can increase the risk of acute myelogenous leukemia. AML is typically experienced the same by those who get this disease. ...Read more

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What is the treatment for acute myeloid leukemia?

What is the treatment for  acute myeloid leukemia?

Differs: The answers depend on patient age, overall health, and type of aml. Usually younger, healthier patients are offered aggressive chemotherapy and possible stem cell transplant, while older patients are offered less aggressive chemotherapy or supportive care alone. Here is a link to info on AML treatment: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient/page1. ...Read more

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Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

See 2 more doctor answers
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What is acute myeloid leukemia (aml)?

Bone marrow cancer: White blood cells live and grow in the bone marrow and enter the blood stream where they travel throughout the body to fight infection. If these cells become cancerous, they grow out of control choking out the normal blood cells in the bone marrow and leaving the person vulnerable to infection, bleeding and anemia because there are not enough normal cells. All ages get AML but usually younger. ...Read more

See 1 more doctor answer
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Acute myeloid leukemia m2 relapse, what to do?

See below...: Relapses of various types of leukemia including AML are still treatable. Consultation with an oncologist to discuss treatment options including chemotherapy and possibly bone marrow or stem cell transplantation is of paramount importance in managing the disease. ...Read more

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Is there anything i can do about acute myeloid leukemia m2 relapse?

See below...: The treatment of leukemia, like any other cancer, should be managed by an oncologist. Many times the relapse is still responsive to chemotherapy and a second remission may be achieved. Subsequent options should be discussed with the oncologist and may include a bone marrow or stem cell transplant. ...Read more

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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