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Doctor insights on: Acute Myelogenous Leukemia Children

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Aml acute myeloid leukemia is what?

Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

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Dr. Aasim Sehbai
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Acute Myelogenous Leukemia (Definition)

This is a type of leukemia. It is a cancer of a certain blood dell, originating in the bone marrow. It causes low blood counts. Diagnosis is often by evaluation of bone marrow aspirate. Treatments depend on subtypes and range from standard chemotherapy ...Read more


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What's acute myeloid leukemia?

What's acute myeloid leukemia?

Blood cancer: AML is a blood cancer affecting a type of white blood cells called myeloid cells. It often occurs in late adult/elderly patients and has a short development phase usually (hence acute). Intensive chemotherapy and often bone marrow transplant can be effective with long term survival in 40-50% cases. AML in the elderly is more difficult to treat and results are worse. ...Read more

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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Is acute myeloid leukemia harmful?

Is acute myeloid leukemia harmful?

Yes! AML can kill.: Acute myeloid leukemia can be very aggressive. Generally it is treated at major clinical centers with a lot of expertise in leukemia especially at first. AML is seen in both children and adults. I would recommend that if either you or a family member is diagnosed with this to seek out a center of excellence. ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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Dangers of chronic myelogenous leukemia?

Dangers of chronic myelogenous leukemia?

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. ...Read more

Dr. Liawaty Ho Dr. Ho
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What percent of leukemias does acute myeloid leukemia represent?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:

AML: AML is the most common acute leukemia in adults and accounts for approximately 80 % of cases in this group. In us and europe, the incidence has been stable at 3 to 5 cases per 100, 000 population. In contrast, AML accounts for less than 10 % of acute leukemias in children less than 10 years of age. ...Read more

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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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Chances of curing acute lymphoblastic leukemia in adults?

Chances of curing acute lymphoblastic leukemia in adults?

See below: About 80-90% of patients will achieve remission, but some of these patients will relapse and not be cured. Overall cure is achieved in about 40%. Those numbers come from this link: http://www.Cancer.Org/cancer/leukemia-acutelymphocyticallinadults/overviewguide/leukemia-all-overview-survival-rates. ...Read more

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What is acute myeloid leukemia (aml)?

What is acute myeloid leukemia (aml)?

Bone marrow cancer: White blood cells live and grow in the bone marrow and enter the blood stream where they travel throughout the body to fight infection. If these cells become cancerous, they grow out of control choking out the normal blood cells in the bone marrow and leaving the person vulnerable to infection, bleeding and anemia because there are not enough normal cells. All ages get AML but usually younger. ...Read more

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What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

Dr. Agos Luca Dr. Luca
6 doctors agreed:
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What is acute lymphoblastic leukemia (all)?

Dr. Agos Luca Dr. Luca
6 doctors agreed:

Blood cancer: All is a form of leukemia which in turn is a form of cancer, more specifically blood and bone marrow cancer. The word "acute" means it progresses faster, as opposed to chronic cases that usually have a slower progression. The word "lymphoblastic" means immature lymphoid and describes the type of malignant cell involved in this leukemia, as opposed to other types of cells, for example myeloid. ...Read more

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Dr. Agos Luca Dr. Luca
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Acute myeloid leukemia m2 relapse, what to do?

Dr. Agos Luca Dr. Luca
3 doctors agreed:
Acute myeloid leukemia m2 relapse, what to do?

See below...: Relapses of various types of leukemia including AML are still treatable. Consultation with an oncologist to discuss treatment options including chemotherapy and possibly bone marrow or stem cell transplantation is of paramount importance in managing the disease. ...Read more

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What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

Types of cells: White blood cells are different with different mechanisms to pretect body from infections. Acute myeloid leukemia arise from a type of white cells called myeloid series or neutophils, cut lymphoblastic leukemiaa arise from lymph type of white cells. These two types of leukemia have different treatments and the outcome or expectations are very different, none is better than the other in general. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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If a person has AML - acut emyeloid leukemia, what percent of blast would suggest acute myeloblastic leukemia?

If a person has AML - acut emyeloid leukemia, what percent of blast would suggest acute myeloblastic leukemia?

Blasts in blood/marr: Blasts are made in the bone marrow. Normally they are under 5% of all the white cells. So a Blast count in the bone marrow over 6% raises the question of Acute leukemia. Anything >30% blast count confirms a diagnosis of acute leukemia. As the blast cell numbers increase in the marrow, Blasts start to appear in the peripheral blood. That is how Leukemia is first diagnosed. ...Read more

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What are complications for someone with acute lymphoblastic leukemia?

What are complications for someone with acute lymphoblastic leukemia?

Many side effects: There are many potential complications for somebody with acute lymphoblastic leukemia (all). Some are related to the leukemia and some are due to toxicities of the treatment. Typical problems include infection, bleeding problems, nausea, vomiting, diarrhea, mouth sores, hair loss, fatigue, and need for blood transfusions. There can be effects on fertility as well. ...Read more

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Differences between myeloid leukemia and lymphoid leukemia?

Differences between myeloid leukemia and lymphoid leukemia?

Type of cell : Lymphoid and myeloid reference the cell type involved in the leukemia. There are different cell types within the lymphoid and within the myeloid groups. We need to identify that cell type to know what treatments will be needed for that specific leukemia.. ...Read more

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What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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What is the definition or description of: acute myelogenous leukemia?

AML: This is a type of leukemia. It is a cancer of a certain blood dell, originating in the bone marrow. It causes low blood counts. Diagnosis is often by evaluation of bone marrow aspirate. Treatments depend on subtypes and range from standard chemotherapy to bone marrow transplant. ...Read more

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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

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What are the treatments available for acute myelogenous leukemia chloroma?

Chloroma is....: A solid leukemia mass, also known as a granulocytic sarcoma, that is traditionally associated with aml. Indeed, chloromas are often associated with specific subtypes of aml, such as those that have the t(8;21) translocation. Treatment for them is the chemotherapy for the disease, although radiation therapy is sometimes used if the chloroma places adjacent structures at risk. Talk with your doctor. ...Read more

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Is revlimid (lenalidomide) effective in the use for treatment for acute myelogenous leukemia?

Possibly: We do use it if they have chromosomal changes that predict response. However, not the standard of care. Mainly used if the person is not in the best of shape and looking for alternative, non aggressive options. Hope this helps. ...Read more

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Does the symptom abdominal pain mean that I have acute myelogenous leukemia?

Hmmmm....: While abdominal pain can be seen in patients with AML at diagnosis, for example from splenic infiltration by leukemia cells, bleeding or clotting episodes, etc., this is far from the first (or even 10th) thing that i think of in a patient with abdominal pain.. I'm wondering why you are making this connection. Sounds like you need to have a frank conversation about this concern with your dr. ...Read more

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What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

See 1 more doctor answer
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Dangers of chronic myelogenous leukemia?

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. ...Read more

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What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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How should I treat chronic myelogenous leukemia?

By oncologist: This is a somewhat indolent form of leukemia which responds to treatment and can be carried for many years without major illenss. You could only have known about this if you had a bone marrow and blood test from your oncologist whose recommendations i would continue to follow. ...Read more

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What are the tests for chronic myelogenous leukemia?

What are the tests for chronic myelogenous leukemia?

Blood, bone marrow: Common tests include blood review, floww cytometry, and a bone marrowe and biopsy. ...Read more

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What are the symptoms of chronic myelogenous leukemia?

Fatigue: Fatigue is the most common symptom. Examination may show an enlarged spleen. The diagnosis is suspected by blood testing and confirmed by bone marrow biopsy. ...Read more

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What kind of disorder is chronic myelogenous leukemia?

Myeloproliferative: It is in a group of disorders referred to as myeloproliferative neoplasms. There are essentially four: chronic myelogenous leukemia, essential thrombocytosis, polycythemia rubra vera and myelofibrosis. Hope this helps. ...Read more

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What sort of disease is chronic myelogenous leukemia (c.M.L.)?

Bcr-abl: CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. ...Read more

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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What are different ways to treat chronic myelogenous leukemia?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
What are different ways to treat chronic myelogenous leukemia?

CML: CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case. ...Read more

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What's the type of inheritance of chronic myelogenous leukemia (cml)?

Not inherited: CML is associated with chromosome damage (the philadelphia chromosome). This is not inherited. The damage is to bone morrow stem cells and occurs long after birth. So the disease is not passed on to children. ...Read more

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What are the tip-offs that you might have chronic myelogenous leukemia?

Symptoms: Many people with CML are found incidentally on blood tests done for an unrelated problem. Symptoms can be bleeding, easy bruising, fatigue, frequent infections, shortness of breath, abdominal fullness, or weight loss. ...Read more

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What is the definition or description of: Chronic myelogenous leukemia?

What is the definition or description of: Chronic myelogenous leukemia?

CML: there are two types of CML ,juvenile and adult . each manifests marked clinical , hematological,and cytogenetic differences. ...Read more

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If you have chronic myelogenous leukemia does that also affect your body externally?

Pallor: Most patient don't show obvious signs. If anemic one might be pale. Enlarged lymph nodes in the neck might be noticeable. If the spleen is big, the abdomen might protrude a bit. Otherwise visible signs usually are lacking. ...Read more

Dr. Liawaty Ho
1,161 doctors shared insights

Leukemia (Definition)

A cancer of blood-forming tissues, hindering the body's ...Read more