Top
10
Doctor insights on: Acute Lymphocytic Leukemia And Neupogen

Share
1

1
What is a karyotype for acute lymphocytic leukemia?

What is a karyotype for acute lymphocytic leukemia?

A karyotype is ...: A technique that lets us see the gross structural features of the chromosomes in a cell. Cells are forced to enter mitosis but then are arrested in metaphase with a drug called nocodazole. The chromosomes can the be seen under the microscop which lets is see their number and structure. All cells can have multiple abnormalities that can be seen by karyotype, but may be normal as well. ...Read more

See 2 more doctor answers
Dr. Liawaty Ho
1,118 doctors shared insights

Leukemia (Definition)

Leukemia is a malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


2

2
Can there be a set karyotype for acute lymphocytic leukemia?

Can there be a set karyotype for acute lymphocytic leukemia?

No. : Gross structural changes in chromosome number and structure can be identified by karyotype. There are many such changes associated with all development, yet many all patients have normal karyotypes. This doesn't mean mutations are absent. Modern techniques let us see changes across the genome at single nucleotide resolution. The critical role of epigenetic change is now also firmly established. ...Read more

See 1 more doctor answer
3

3
Please describe the mortality rate for acute lymphocytic leukemia?

Please describe the mortality rate for acute lymphocytic leukemia?

Differs depending...: On the subtype of all, age and risk stratification. Pts with b-cell phenotypes tend to do better than those with t-cell dz. Children tend to do better than adolescents and adults. There are also several molecular abnormalities with prognostic significance. Not enough room here to list. Taking all comers, survival among adults is 40-50% while for children, 80-85%. Ask if you need more specifics. ...Read more

See 1 more doctor answer
4

4
If a child has acute lymphocytic leukemia, can he continue with regular schooling?

If a child has acute lymphocytic leukemia, can he continue with regular schooling?

Interrupted: The regular schooling will be interrupted for several months to a year perhaps or could be a bit longer sometimes- while receiving chemotherapy and +/- if transplantation is required. After everything is completed and if complete cure is achieved- and no major complication from the treatment, he should/would be able to resume regular schooling. ...Read more

See 1 more doctor answer
5

5
Is there a karyotype for acute lymphocytic leukemia?

Is there a karyotype for acute lymphocytic leukemia?

Yes: Chromosomal abnormalities, such as t(9;22)(q34;q11) (abl/bcr), t(12;21)(p13;q22) (tel/aml1), and t(11q23) (mll) are independent prognostic indicators in childhood acute lymphoblastic leukemia. ...Read more

See 1 more doctor answer
6

6
Help! what is acute lymphocytic leukemia in a chronic stage?

Help! what is acute lymphocytic leukemia in a chronic stage?

I believe you have: These diagnoses confused. Chronic leukemias display an elevated # of wbcs with morphologic and functional features similar to the mature cells of that lineage (lymphoid-cll vs myeloid-cml). Think of it as not turning off the spigot when the bucket is full. Acute leukemias have features of immature cells for a lineage (aml vs all). Acute leukemias can arise from chronic ones. This is blast crisis. ...Read more

See 2 more doctor answers
7

7
How rare is it for a child to have acute lymphocytic leukemia?

How rare is it for a child to have acute lymphocytic leukemia?

2.8/100,000: Acute leukemia is the most common form of cancer in children, comprises approximately 30% of all childhood malignancies, with acute lymphoblastic leukemia being 5 times more common than acute myeloid leukemia. Approximately 2500 to 3500 new cases of all are diagnosed in children each year in the United States with an incidence of 2.8 cases per 100, 000. ...Read more

8

8
How frequently can relapse occur in acute lymphocytic leukemia (all)?

20-30: It depend to the type of ALL ,B cell ,T cell ,age of diagnosis ,bellow 2 years or above 9 years ,CNS involvement at diagnosis,but about 20-25% ...Read more

9

9
My friend found out she has acute lymphocytic leukemia today. What can she expect?

Chemotherapy: All is generally curable in children, less so in adults. See this site for more info. http://www.mayoclinic.com/health/acute-lymphocytic-leukemia/ds00558. ...Read more

See 1 more doctor answer
10

10
How is the blood affected in a patient with acute lymphocytic leukemia?

How is the blood affected in a patient with acute lymphocytic leukemia?

Different ways: Although the word leukemia refers to cancerous white cells in the blood, many times the disease is growing so fast in the bone marrow that these cells never enter the blood and also, since they crowd out normal blood cells in the marrow, these are also decreased or absent in the blood leading to problems with infection, bleeding profound weakness. ...Read more

See 2 more doctor answers
Dr. Michael Engel
55 doctors shared insights

Acute Lymphoblastic Leukemia (Definition)

Also known as acute lymphocytic leukemia, acute lymphoblastic leukemia is a cancer of the white blood cells. There is an overproduction of immature white blood cells called lymphoblasts in the bone marrow. Symptoms of this cancer are anemia, dizziness, fatigue, ...Read more