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Doctor insights on: Acute Lymphocytic Leukemia

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What's acute myeloid leukemia?

What's acute myeloid leukemia?

See links: For a nice overview of aml, see the following pages at the national cancer institute. For adult: http://www.Cancer.Gov/cancertopics/pdq/treatment/adultaml/patient for pediatric: http://www.Cancer.Gov/cancertopics/pdq/treatment/childaml/patient. ...Read more

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Dr. Liawaty Ho
1,149 doctors shared insights

Leukemia (Definition)

A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow ...Read more


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Aml acute myeloid leukemia is what?

Aml acute myeloid leukemia is what?

AML is a cancer.....: Of the bone marrow (actually a group of cancers) whose precise causes are unknown, but about which we know considerable molecular detail and are learning more each day. The disease arises from the hematopoietic stem/progenitor cells in the bone marrow when these cells acquire mutations that allow them to escape controls on growth and apoptosis. Subtype info is found on the nci website. ...Read more

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How is acute myeloid leukemia different from chronic lymphoma leukemia?

How is acute myeloid leukemia different from chronic lymphoma leukemia?

Different cell type: Leukemias typically originate when one of the white blood cell types starts multiplying out of control and preventing the normal cells from doing their job. There are many types of white blood cells and the subtype of leukemia or lymphoma or myeloma depends on which subtype is out of control. ...Read more

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What causes acute myelogenous leukemia?

What causes acute myelogenous leukemia?

DNA mutations: Leukemias occur due to mutations in dna. Many mutations have been linked to aml, however, the cause for most of the mutations remains unclear. Known risks include radiation exposure and certain chemical exposure. ...Read more

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Is acute myeloid leukemia harmful?

Yes! AML can kill.: Acute myeloid leukemia can be very aggressive. Generally it is treated at major clinical centers with a lot of expertise in leukemia especially at first. AML is seen in both children and adults. I would recommend that if either you or a family member is diagnosed with this to seek out a center of excellence. ...Read more

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What is chronic myeloid leukemia?

What is chronic myeloid leukemia?

Marrow cancer: CML is a marrow malignancy characterized by excessive number of white blood cells with various degrees of maturation. Most CML patients have deficient number of red cells and platelets. CML responds dramatically to oral agents called tyrosine kinase inhibitors. Examples are Gleevec and Sprycel (dasatinib). ...Read more

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What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

What is the difference between acute myeloid leukemia vs acute lymphocytic leukemia?

Types of cells: White blood cells are different with different mechanisms to pretect body from infections. Acute myeloid leukemia arise from a type of white cells called myeloid series or neutophils, cut lymphoblastic leukemiaa arise from lymph type of white cells. These two types of leukemia have different treatments and the outcome or expectations are very different, none is better than the other in general. ...Read more

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What percent of leukemias does acute myeloid leukemia represent?

AML: AML is the most common acute leukemia in adults and accounts for approximately 80 % of cases in this group. In us and europe, the incidence has been stable at 3 to 5 cases per 100, 000 population. In contrast, AML accounts for less than 10 % of acute leukemias in children less than 10 years of age. ...Read more

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What is acute myeloid leukemia (aml)?

What is acute myeloid leukemia (aml)?

Bone marrow cancer: White blood cells live and grow in the bone marrow and enter the blood stream where they travel throughout the body to fight infection. If these cells become cancerous, they grow out of control choking out the normal blood cells in the bone marrow and leaving the person vulnerable to infection, bleeding and anemia because there are not enough normal cells. All ages get AML but usually younger. ...Read more

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Acute myeloid leukemia m2 relapse, what to do?

Acute myeloid leukemia m2 relapse, what to do?

See below...: Relapses of various types of leukemia including AML are still treatable. Consultation with an oncologist to discuss treatment options including chemotherapy and possibly bone marrow or stem cell transplantation is of paramount importance in managing the disease. ...Read more

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

Dr. Agos Luca Dr. Luca
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What is acute lymphoblastic leukemia (all)?

Dr. Agos Luca Dr. Luca
6 doctors agreed:

Blood cancer: All is a form of leukemia which in turn is a form of cancer, more specifically blood and bone marrow cancer. The word "acute" means it progresses faster, as opposed to chronic cases that usually have a slower progression. The word "lymphoblastic" means immature lymphoid and describes the type of malignant cell involved in this leukemia, as opposed to other types of cells, for example myeloid. ...Read more

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What is chronic myelogenous leukemia?

What is chronic myelogenous leukemia?

A blood cancer: CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. ...Read more

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What is acute myeloid leukemia is?

Marrow malignancy: AML is a bone marrow malignancy characterized by uncontrolled growth of leukemic cells in the bone marrow. It leads to very high white blood cell counts, anemia and thrombocytopenia (low platelets). It is rapidly fatal without prompt diagnosis and treatment. It can be cured in up to about 40% of people. ...Read more

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Differences between myeloid leukemia and lymphoid leukemia?

Differences between myeloid leukemia and lymphoid leukemia?

Type of cell : Lymphoid and myeloid reference the cell type involved in the leukemia. There are different cell types within the lymphoid and within the myeloid groups. We need to identify that cell type to know what treatments will be needed for that specific leukemia.. ...Read more

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What is chronic myelogenous leukemia (cml)?

What is chronic myelogenous leukemia (cml)?

White cell cancer: The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. ...Read more

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Dangers of chronic myelogenous leukemia?

Can be fatal: This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. ...Read more

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What is acute leukemia?

It is a disease: Acute leukemia is a blood disorder where white cells are not formed normally. It has excellent treatment available now. ...Read more

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Is cll leukemia curable?

Is cll leukemia curable?

Only sometimes...: I agree cll is not curable for most patients. For some patients who are robust, a consultation at a marrow /stem cell transplant center is warranted as there are investigational approaches that have helped some patients, some who appear cured. A note of caution- bone marrow transplant is the riskiest thing one can do to try to treat this disease and may lead to earlier death though. ...Read more

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Dr. Michael Engel
57 doctors shared insights

Acute Lymphoblastic Leukemia (Definition)

Also known as acute lymphocytic leukemia, it is a cancer of the white blood cells. It occurs when there is an overproduction of immature white blood cells called lymphoblasts ...Read more