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Doctor insights on: Acute Glomerulonephritis Pathophysiology

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What usually precedes acute glomerulonephritis?

What usually precedes acute glomerulonephritis?

Acute GN: Often acute glomerulonephritis happens after strep infection (skin or throat) i.e. Post strep gn, or an upper respiratory infection (iga nephropathy). Otherwise, there is not necessarily any preceding event. ...Read more

Dr. Patrick Sweet III
123 doctors shared insights

Glomerulonephritis (Definition)

The acute inflammation of the kidney, typically caused ...Read more


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Why does acute glomerulonephritis usually decrease urine output?

Changes in function: One of the defining features of glomerulonephritis is an alteration in the kidney function. One of the functions of the kidneys is to help regulate fluid balance. So if the kidneys are affected by glomerulonephritis, fluid balance may be compromised. ...Read more

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Relation between acute glomerulonephritis and having a C3 compliment?

C3: A low c3 level with gn would point to an autoimmumme process that needs treatment. ...Read more

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Explain the general difference between acute glomerulonephritis and chronic glomerulonephritis. How is each treated?

Diagnosis: Acute glomerulonephritis means onset of kidney inflammation in days, so cause should be identified, treated , to recover renal function. Chronic means the problem existed for few weeks - months, still cause should be diagnosed, treated.Most often , both requires renal biopsy. ...Read more

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What is the difference between acute pyelonephritis and acute glomerulonephritis?

Here are some...: Pyelonephritis denotes kidney infection usually extended from its hollow part called renal pelvis, but occasionally maybe a blood-borne infection to kidneys. Glomerulonephritis denotes inflammatory change specifically affecting microfilters (glomeruli) & their associated tubules, which usually result from streptococcal infection, autoimmune disorders, drugs, diseases like diabetes or hypertension. ...Read more

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Why does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Why  does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Leakage of protein,,: This is likely due to the fact that there is failure of the basement membrane to contain large molecules like proteins, etc.. Also in some cases, oliguria can occur, which means anything in the urine can get concentrated even more than it should be. Proteinuria can be almost 3 g/day. ...Read more

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How to diagnose Acute Glomerulonephritis and What is Treatment? As my creatinine is increasing, have back pain and RBC in urine from last 3 months.

How to diagnose Acute Glomerulonephritis and What is Treatment?
As my creatinine is increasing, have back pain and RBC in urine from last 3 months.

After: ALL the non-invasive testing is done, RENAL BIOPSY may be and often is an ABSOLUTE "requirement" to assess the status of renal tissue! Hope this helps! Dr Z ...Read more

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Chronic glomerulonephritis pathophysiology?

Complex: Reduction in nephron mass from an injury reduces the gfr. This reduction causes hypertrophy & hyperfiltration of the remaining nephrons & to intraglomerular hypertension. These changes occur to increase the GFR of the remaining nephrons, thus minimizing the functional consequences of nephron loss. The changes are ultimately detrimental because they lead to glomerulosclerosis & further nephron loss. ...Read more

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I've been diagnosed with mild chronic Glomerulonephritis. What can I do to prevent it from developing to acute stage?

Avoid some medicatio: If you have chronic kindney disease you can prevent worsening of Kinsey function by avoiding medications which worsen kidney function. You should avoid medications such as Ibuprofen (Motrin, Advil) and Naproxen (Aleve, Naprosyn). When in doubt ask your doctor or pharmacist. Always read the ingredient labels of multisymptom medications before taking them. ...Read more

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Can IgA and resolving post-infectious glomerulonephritis be differentiated without biopsy? Also, can the acute onset of post-inf gl be asymptomatic?

Need a biopsy: Both IgA and post infectious gn may look similar even on biopsy. Without biopsy can be different in presentation . Post infectious gn can be without symptoms. ...Read more

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With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

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Does chronic glomerulonephritis cause severe pain?

Does chronic glomerulonephritis cause severe pain?

See below: The common causes of kidney pain are kidney stones, infection and cyst rupture in polycystic kidney disease, besides kidney trauma from any cause and there is a condition called loin pain hematuria syndrome. Besides the above generally speaking chronic glomerulonephritis does not cause kidney pain get yourself examined for other causes. ...Read more

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What is focal sclerosing glomerulonephritis? What causes it?

Pattern: This may be due to anything from IgA nephropathy to lupus to a vasculitis. It's not a specific disease but a pattern of injury. As for more details. ...Read more

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Does experiencing post streptococcal glomerulonephritis when young, increases the risk of experiencing it again during adulthood?

Infection : If it clears up completely with treatment then you should be fine. However in some cases a chronic state develops and this can lead to end stage renal disease and eventually renal transplant or dialysis. It is very important to make sure that the infection is totally cleared ...Read more

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I hve glomerulonephritis, controlled bp. I used to consume a lot of cane vinegar whenever i eat. Does vinegar hve bad effects to my kidney?

I hve glomerulonephritis, controlled bp. I used to consume a lot of cane vinegar whenever i eat. Does vinegar hve bad effects to my kidney?

Vinegar and CKD: no adverse effect on kidneys on use of Vinegar in moderation. There are some reported benefit of kidney function on use of vinegar regularly but none of those substantiated with strict scientific research study. ...Read more

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Glomerulonephritis, can you explain this?

Glomerulonephritis: It means inflammation (due to cellular infiltration, autoimmune diseases, or infectious causes) in the glomeruli (which are smart tiny building blocks of your kidneys-where all the clearance of toxins from your blood happen!) it is diagnosed by kidney biopsy and many urine and blood tests. Symptoms and signs can be swelling of legs/face, blood and/or protein in urine, hypertension, abnl kidney fx ...Read more

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Glomerulonephritis. How rare is it in young adults?

Glomerulonephritis. How rare is it in young adults?

Rare, but happens: Young adults can get focal segmental disease that causes high blood pressure and proteing loss. Other forms of gn also occur. The diagnosis depends on urinalysis and kidney biopsy. Many are treatable but not all depending on type. Obesity can cause gn. Also, drug abuse is more common in younger adults and can cause gn. ...Read more