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Doctor insights on: Acute Glomerulonephritis Pathophysiology

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What usually precedes acute glomerulonephritis?

What usually precedes acute glomerulonephritis?

Acute GN: Often acute glomerulonephritis happens after strep infection (skin or throat) i.e. Post strep gn, or an upper respiratory infection (iga nephropathy). Otherwise, there is not necessarily any preceding event. ...Read more

Dr. Patrick Sweet III
121 doctors shared insights

Glomerulonephritis (Definition)

The acute inflammation of the kidney, typically caused ...Read more


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Why does acute glomerulonephritis usually decrease urine output?

Changes in function: One of the defining features of glomerulonephritis is an alteration in the kidney function. One of the functions of the kidneys is to help regulate fluid balance. So if the kidneys are affected by glomerulonephritis, fluid balance may be compromised. ...Read more

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Relation between acute glomerulonephritis and having a C3 compliment?

C3: A low c3 level with gn would point to an autoimmumme process that needs treatment. ...Read more

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Explain the general difference between acute glomerulonephritis and chronic glomerulonephritis. How is each treated?

Diagnosis: Acute glomerulonephritis means onset of kidney inflammation in days, so cause should be identified, treated , to recover renal function. Chronic means the problem existed for few weeks - months, still cause should be diagnosed, treated.Most often , both requires renal biopsy. ...Read more

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What is the difference between acute pyelonephritis and acute glomerulonephritis?

Here are some...: Pyelonephritis denotes kidney infection usually extended from its hollow part called renal pelvis, but occasionally maybe a blood-borne infection to kidneys. Glomerulonephritis denotes inflammatory change specifically affecting microfilters (glomeruli) & their associated tubules, which usually result from streptococcal infection, autoimmune disorders, drugs, diseases like diabetes or hypertension. ...Read more

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Why does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Why  does in acute glomerulonephritis , specific gravity &urine osmolality increase ?Shouldn't kidneys loss the ability to concentrate the urine?

Leakage of protein,,: This is likely due to the fact that there is failure of the basement membrane to contain large molecules like proteins, etc.. Also in some cases, oliguria can occur, which means anything in the urine can get concentrated even more than it should be. Proteinuria can be almost 3 g/day. ...Read more

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How to diagnose Acute Glomerulonephritis and What is Treatment? As my creatinine is increasing, have back pain and RBC in urine from last 3 months.

How to diagnose Acute Glomerulonephritis and What is Treatment?
As my creatinine is increasing, have back pain and RBC in urine from last 3 months.

After: ALL the non-invasive testing is done, RENAL BIOPSY may be and often is an ABSOLUTE "requirement" to assess the status of renal tissue! Hope this helps! Dr Z ...Read more

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Chronic glomerulonephritis pathophysiology?

Complex: Reduction in nephron mass from an injury reduces the gfr. This reduction causes hypertrophy & hyperfiltration of the remaining nephrons & to intraglomerular hypertension. These changes occur to increase the GFR of the remaining nephrons, thus minimizing the functional consequences of nephron loss. The changes are ultimately detrimental because they lead to glomerulosclerosis & further nephron loss. ...Read more

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I've been diagnosed with mild chronic Glomerulonephritis. What can I do to prevent it from developing to acute stage?

Avoid some medicatio: If you have chronic kindney disease you can prevent worsening of Kinsey function by avoiding medications which worsen kidney function. You should avoid medications such as Ibuprofen (Motrin, Advil) and Naproxen (Aleve, Naprosyn). When in doubt ask your doctor or pharmacist. Always read the ingredient labels of multisymptom medications before taking them. ...Read more

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Can IgA and resolving post-infectious glomerulonephritis be differentiated without biopsy? Also, can the acute onset of post-inf gl be asymptomatic?

Need a biopsy: Both IgA and post infectious gn may look similar even on biopsy. Without biopsy can be different in presentation . Post infectious gn can be without symptoms. ...Read more