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Doctor insights on: Acute Fatty Liver Of Pregnancy

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Dr. Brad Goldenberg
2 doctors shared insights

Liver (Definition)

This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more


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What is the treatment for acute fatty liver of pregnancy?

What is the treatment for acute fatty liver of pregnancy?

Delivery of baby: Because the patient usually presents with liver failure, kidney failure, and whole host of associated potentially life threatening conditions, the best option is to get the baby delivered and then deal with all of the maternal complications. Maternal and fetal mortality approaches 25% and may even require liver transplant for the mother. ...Read more

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Are some people more prone to getting acute fatty liver of pregnancy?

Are some people more prone to getting acute fatty liver of pregnancy?

Yes: Anyone who has had acute fatty liver of pregnancy (AFP) is at about a 25% risk for recurrence with future pregnancies. The initial episode appears to have a genetic predisposition due to an autosomal recessive gene defect. There is no current recommendation to screen for this genetic defect. The incidence of AFP is around 1 in 10, 000 pregnancies. ...Read more

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Can they only diagnose acute fatty liver of pregnancy if you die?

No: Biopsy(a very skinny needle)into the liver can confirm this diagnosis of liver disease. ...Read more

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Are some people more prone to getting acute fatty liver of pregnancy?

Yes: Anyone who has had acute fatty liver of pregnancy (AFP) is at about a 25% risk for recurrence with future pregnancies. The initial episode appears to have a genetic predisposition due to an autosomal recessive gene defect. There is no current recommendation to screen for this genetic defect. The incidence of AFP is around 1 in 10, 000 pregnancies. ...Read more

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Do lots of people get acute fatty liver of pregnancy, or is it unusual?

Do lots of people get acute fatty liver of pregnancy, or is it unusual?

Uncommon: Acute fatty liver of pregnancy (AFP) is rare, occurring in about 1 in 10, 000 pregnancies. It is quite serious and can be fatal (to mom and / or baby) - good outcomes require prompt diagnosis and treatment, which usually incudes delivery of the baby as soon as the mother is stable. Recurrance risk is about 25% for subsequent pregnancies. ...Read more

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Suspecting acute fatty liver of pregnancy. What will do this to my wife?

Suspecting acute fatty liver of pregnancy. What will do this to my wife?

Serious condition: Acute fatty liver of pregnancy is a serious condition. It can be life threatening to both mother and baby. Treatment is immediate delivery. Unfourtunately, it can recur in the subsequent pregnancy. So, recommendation is to avoid future pregnancy. ...Read more

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What is acute fatty liver of pregnancy?

What is acute fatty liver of pregnancy?

Fatty liver: Acute fatty liver of pregnancy (aflp) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. Although the exact pathogenesis is unknown, this disease has been linked to an abnormality in fetal fatty acid metabolism. Early diagnosis of aflp sometimes can be difficult because it shares features with other common conditions such as pre-eclampsia, vira. ...Read more

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How common is it for somebody to get acute fatty liver of pregnancy?

Rare: Acute fatty liver of pregnancy is rare. It has an estimated incidence of 1 in 7000 to 1 in 20, 000 deliveries. It is more common in patients with multiple gestations and maybe in women who are underweight. ...Read more

Dr. Louis Gallia
11 doctors shared insights

Pregnancy (Definition)

If you're pregnant or planning to get pregnant, there are many things you can do to give your baby a healthy start: Regular prenatal visits along with laboratory testing, ultrasounds, prenatal vitamins and immunizations (like the flu shot and whopping cough booster). Now's the time to eat healthy, stay hydrated, and ...Read more


Dr. Amrita Dosanjh
1 doctor shared a insight

Fatty Liver (Definition)

Some fat in the liver is normal. But if fat makes up more than 5%-10% of the weight of your liver, you may have alcoholic or nonalcoholic liver disease. In some cases, these diseases can ...Read more