Top
10
Doctor insights on: Actos And Bladder Cancer

Share
1

1
Is what they are saying about actos (pioglitazone) causing bladder cancer true?

Is what they are saying about actos (pioglitazone) causing bladder cancer true?

Possibly: There is evidence of an excess number of cases of bladder cancer in patients who have taken the drug Actos (pioglitazone) compared to what might normally be expected in a large group of people. Epidemiologic research in this regard continues, but it may be prudent for those who have taken the drug for longer than 1 year to be screened for this, especially in patients with other risk factors such as smoking. ...Read more

See 1 more doctor answer
Dr. Barry Rosen
4,224 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


2

2
Why is actos (pioglitazone) still on market although it's confirmed to cause bladder cancer?

Why is actos (pioglitazone) still on market although it's confirmed to cause bladder cancer?

Not conclusive: There is not confirmation that it causes bladder cancer. The study you are mentioning was done in france where there is a very high percentage of smokers. Smoking can increase the level of bladder cancer. Kaiser is currently doing a large study to see if there is any association. Most of us still use Actos (pioglitazone) with our patients. Diabetes can be a bad disease also. ...Read more

3

3
I take 30 mg of actos (pioglitazone) for type 2 diabetes daily. It has been linked to increased risk of bladder cancer in person taking actos (pioglitazone). Is actors safe?

See answer: There has been a slight excess of bladder cancers detected in patients who have taken Actos (pioglitazone) compared to others who do not. This appears to be time and dose dependent. Very few people who take Actos (pioglitazone) will develop bladder cancer. However there are many alternatives so it makes sense to switch to another drug if that will be effective , . ...Read more

5

5
Is bladder cancer serious?

Is bladder cancer serious?

Yes: Most bladder cancers diagnosed in the us are, however, very early in their presentations (stages 0 or 1), and therefore curable. However, a neglected bladder cancer will progress to a more advanced form of cancer that may become incurable and lethal. Therefore, it is important to take care of this as soon as possible. ...Read more

See 2 more doctor answers
6

6
Is bladder cancer painful?

Maybe: Bladder cancer is generally not painful until it has spread to local organs and structures. If it contained to the superficial lining of the bladder without invasion, it is usually not painful. ...Read more

See 1 more doctor answer
7

7
Is bladder cancer hereditary?

Is bladder cancer hereditary?

No: Tobacco and environmental exposures to dyes for urothelial cancer; schistosoma hematobium, a parasite in egypt and chronic csatheterization for squamous cancr, and adenocarcinoma related to remnants of the urachus, the foetal conduit of urinary exretion through umbilicus into placental circulation...In this last case one might say "inborn error" but not genetic or hereditary. ...Read more

See 1 more doctor answer
8

8
How serious is bladder cancer?

Serious: One can die from bladder cancer if that helps you understand it's gravity. The most common risk factor for bladder cancer is smoking. Do not smoke! ...Read more

See 1 more doctor answer
9

9
Can you die from bladder cancer?

Can you die from bladder cancer?

Yes: Bladder cancer can invade from the lining into the muscle and deeper. From that point it can spread to pelvic lymph nodes or into the bloodstream. If it gets this far even with therapy with chemotherapy the disease may not be controlled and eventually kill the patient. ...Read more

See 2 more doctor answers
10

10
How dangerous is bladder cancer?

Depends: There are various grades of bladder cancer to determine how aggressive the cancer is. Cancers that are very aggressive and multifocal tend to be much more dangerous than other types of bladder that are more similar to normal bladder cells. If these very aggressive tumors are not treated appropriately, they tend to metastasize and spread over time. Once this occurs, the long term prognosis is poor. ...Read more

See 2 more doctor answers

Bladder (Definition)

The bladder is a muscular organ in the pelvis that accepts urine from the kidneys, stores the urine at low pressure, & expels the urine during voluntary voiding. Though seemingly a simple reservoir, the bladder is a complex organ intricately connected with the brain and spinal cord with sensory, motor, and autonomic circuits. The muscular layer that contracts during voids ...Read more


Dr. Terence Chapman
282 doctors shared insights

Bladder Cancer (Definition)

The bladder is the organ which holds urine. It may develop cancer as with any organ. There are two types: superficial bladder cancer and muscle invasive bladder cancer. The differences are important as they ...Read more