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Doctor insights on: Acquired Von Willebrand Disease

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What is von willebrand disease?

What is von willebrand disease?

Bleeding disorder: Vwd is the most common inherited bleeding disorder. Von wiilebrand factor is a clotting protein that helps stabilize clots by helping to bind platelets together and also helps carry factor viii in the blood. In vwd, vw factor is either decreased or does not function appropriately. Clots will form but they are not stable, can easily fall apart/ dissolve, and bleeding will then occur. ...Read more

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Dr. Joseph Torkildson
49 doctors shared insights

Von Willebrand (Definition)

Von Willebrand disease is caused by a deficiency of von Willebrand factor. Von Willebrand factor helps blood platelets clump together and stick to the blood vessel wall, which is necessary for normal blood clotting. There are several types ...Read more


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What is von willebrand's disease?

What is von willebrand's disease?

Von Willebrand ....: Factor . Vwf is a glycoprotein important for primary hemostasis. It cross links collagen at a site of injury with gpib on platelets. Deficiency leads to failure of primary hemostasis (ie, bleeding). Vwf also protects fviii from degradation. Fviii also promotes clotting. So, vwf deficiency also causes secondary fviii dysfunction. Vwf def has many variants. Severity is variable. Most have type i. ...Read more

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Does von willebrand's disease involve bruising easily?

Does von willebrand's disease involve bruising easily?

Yes: Symptoms of VWD may include increased bruising. Other types of bleeding typically seen include nose bleeds, prolonged menstrual periods, prolonged bleeding after surgery or injury, mucous membrane bleeding. Vwd usually does not present with spontaneous joint bleeding / deep tissue bleeding as is seen in the hemophilias. ...Read more

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What is von willebrand's disease ?

What is von willebrand's disease ?

A bleeding problem: Platelets stop bleeding by patching holes in blood vessels. von Willebrand factor is the glue that sticks platelets to those holes. If von Willebrand factor is low, or if the structure of VWF is abnormal, it doesn't stick platelets to the sites of bleeding. Most people have nosebleeds, gum bleeding, or bleeding after tooth extraction. There are 4 types of VW disease with different symptoms. ...Read more

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Could people with von willebrand disease or hemophilia get tattoos?

Could people with von willebrand disease or hemophilia get tattoos?

Yes: Like everything else involving body art, it's at your own risk. Your physician might be your best guide here. If you take a factor before other procedures, this would perhaps be a good time. Start with something small. I like well-chosen body art and if this is something you've really wanted for some time, i hope you're able to get it. ...Read more

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How common is von hippel-lindau disease?

How common is von hippel-lindau disease?

Von Hippel-Lindau: Von hippel-lindau syndrome is an inherited disorder characterized by the formation of tumors and fluid-filled sacs (cysts) in many different parts of the body. Tumors may be either noncancerous or cancerous and usually appear during young adulthood; however, the signs and symptoms of von hippel-lindau syndrome can occur throughout life. ...Read more

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What is von willebrand's disease type 3?

What is von willebrand's disease type 3?

VonWillebrand type 3: This is severe von willebrand disease. These people may have a total absence of von willebrand factor, and factor viii levels are often less than 10%. Usually inherited in recessive manner (one affected gene from each parent who may not have symptoms). It is essential to see a pediatric hematologist for this disease. ...Read more

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Could people with von willebrand disease get tattoos?

Could people with von willebrand disease get tattoos?

Yes: Most people with von Willebrand's don't know they have it. If you have a severe form and are followed regularly by a hematologist, ask him/her first. Otherewise, go ahead. Be sure it's something you really and truly want. Best wishes. ...Read more

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Ayurvedic treatment for von hippel lindau disease?

Ayurvedic treatment for von hippel lindau disease?

Questionable: Others might disagree, and certainly ayurvedic treatment can be used along with other things if it makes you feel better, but I would concentrate on traditional treatments and diagnoses for this very serious syndrome ...Read more

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Can people with von willebrand disease get tattoos done?

It is possible, but: Depending on the severity of your disease, it is possible, but only in consultation with your hematologist. The severity of VWD is quite variable from patient to patient. If you really wanted to get a tattoo, you could pre-treat yourself with the appropriate medicine as if you were having an elective surgery, but you would have to pay for it out of pocket (i doubt insurance would cover it). ...Read more

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Is von willebrand disease considered risky for women?

Is von willebrand disease considered risky for women?

Not necessarily: "risky" is hard to define. Because menstrual bleeding is one of the more common problems women with VWD have, it is considered "riskier" for women than men. It is very possible to manage menstrual bleeding, as well as bleeding with childbirth very effectively, however. Once that happens, VWD is no riskier for women than it is for men. ...Read more

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Is there a genetics connection von hippel-lindau disease?

Is there a genetics connection von hippel-lindau disease?

Von Hippel-Lindau: Von hippel-lindau syndrome is an inherited disorder characterized by the formation of tumors and fluid-filled sacs (cysts) in many different parts of the body. Tumors may be either noncancerous or cancerous and usually appear during young adulthood; however, the signs and symptoms of von hippel-lindau syndrome can occur throughout life. ...Read more

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Is sickle recessive anemia a sex-linked disease?

Is sickle recessive anemia a sex-linked disease?

If you mean....: Is the beta globin gene transmitted on a sex chromosome (either x or y), the answer is no. The beta globin locus is autosomal, and classical sickle cell disease (hgbss disease) displays autosomal recessive inheritance. Boys and girls are equally likely to inherit the beta-s allele from an affected or carrier parent, and if they inherit a beta-s allele from each parent, they will have disease. ...Read more

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Is there a genetic basis for von willebrand disease?

Yes: Vwd is an inherited condition. It affects both males and females. If one parent has the most common type, type 1, then each child has a 50% chance of inheriting the disease. ...Read more

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What are von hippel - lindau disease and lennox/gastaut syndrome.?

What are von hippel - lindau disease and lennox/gastaut syndrome.?

Syndromes: Von Hippel-Lindau syndrome is a genetic disorder that leads to the developement of many different types of tumors. Lennox Gastaut syndrome is a disorder in which the victim has many seizures. Both are severe, and a person with either one should have a doctor familiar with its treatment ...Read more

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Is sickle cell disease genetic?

Is sickle cell disease genetic?

Yes: The recessive sickle gene is carried silently in a percentage of the population.When two carriers produce offspring their is 25% risk with each conception that an affected baby will be born. ...Read more

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What is type 3 von willebrand's disorder?

What is type 3 von willebrand's disorder?

Homozygous vWD: Pts with type 3 VWD have loss or mutations of both vwf genes, and produce almost no vwf protein. Clinically they behave like severe hemophilia a patients as their factor viii levels are very low as well, since vwf also carries factor viii in the blood. ...Read more

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What causes von hippel lindau?

What causes von hippel lindau?

Genetic: Von hippel–lindau disease is a genetic condition caused by a mutation of the “von hippel-lindau tumor suppressor” gene on chromosome 3 .It is autosomal dominant. ...Read more

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Can von willebrand disease interfere with getting pregnant?

Can von willebrand disease interfere with getting pregnant?

It should not: Von willebrand's disease is a condition where a deficiency or abnormality in a protein in the blood leads to an increased risk of certain types of bleeding. While it might make labor and delivery more challenging, it should not affect a woman's ability to become pregnant. ...Read more