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Doctor insights on: Acquired Adrenal Hyperplasia

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What is adrenal hyperplasia?

What is adrenal hyperplasia?

Adrenal: Enlargement of the adrenal gland. Small gland that sits on top of kidneys. ...Read more

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Could you explain what is a adrenal hyperplasia ?

Could you explain what is a adrenal hyperplasia ?

CAH?: Do you mean congenital adrenal hyperplasia? There are adult forms of this. It occurs when there is an enzyme defect in adrenal steroid synthesis such that excess adrenal androgens are made. In extreme cases, female babies are born with male-like genitalia. In mild forms, it looks like pcos in adulthood. Treatment can be complicated, and should be by an endocrinologist (medicine or gyn). ...Read more

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My baby has taken two test one showed he didn t have congential adrenal hyperplasia and the other should he actually did what I should I do?

My baby has taken two test one showed he didn t have congential adrenal hyperplasia and the other should he actually did what I should I do?

Depends on situation: The first screening test done at a day or so can be falsely positive. The second screening test done at a week or later is more accurate. There are specific tests that can be done on the blood to sort out confusing results & are usually done with the aid of a metabolic specialist or pediatric endocrinologist. ...Read more

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What is congenital adrenal hyperplasia?

What is congenital adrenal hyperplasia?

Enzyme defeciency: This disease results from deficiency of an enzyme, 21 hydroxylase, that is essential for synthesis of adrenal hormones. Block in the synthesis of glucoroticoids causes excess production of male sex hormones. See this site for more information.
http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001448/. ...Read more

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Who has congenital adrenal hyperplasia?

Who has congenital adrenal hyperplasia?

Enzyme deficiency: Deficiency of 21 hydroxylase enzyme needed for synthesis of gluco- and mineralo-corticoids causes excessive production of sex hormones, mainly male sex hormones. The result is endocrine disturbance in both boys and girls and virilization in girls. ...Read more

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How long should congenital adrenal hyperplasia last?

How long should congenital adrenal hyperplasia last?

Forever: This is a lifelong genetic issue. Medication & monitoring can decrease the impact on one's life, but it is not like a pneumonia, it doesn't go away after treatment. ...Read more

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What are the tests for congenital adrenal hyperplasia?

What are the tests for congenital adrenal hyperplasia?

ADRENAL HYPERPLASIA: Serum levels of 17-hydroxy progesterone, cortisol, corticosterone, Progesterone are low and dhea, androstenedione are high. ...Read more

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What sort of disease is congenital adrenal hyperplasia?

What sort of disease is congenital adrenal hyperplasia?

Missing enzyme: There are different types. They all involve a deficiency of an enzyme needed in cortisol production. Since the pituitary senses there isn't enough cortisol, it keeps trying to make the adrenals make cortisol. But because that enzyme is missing, the building blocks of cortisol build up. These substances get turned into androgens - male hormones - and cause abnormalities in sexual development. ...Read more

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What are the symptoms of congenital adrenal hyperplasia?

What are the symptoms of congenital adrenal hyperplasia?

Classic or non?: Classic cah is diagnosed mostly on newborn screening. It results from a block in the synthesis of cortisol and usually also aldosterone. Females will often have ambiguous genitalia. Males don't look different. Permanent replacement with Hydrocortisone & Fludrocortisone (may not need past childhood) are needed for sustaining life and salt balance. Pediatric endocrinologists follow very closely. ...Read more

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Do the symptoms of congenital adrenal hyperplasia differ by gender?

Yes: Persons with the most common form congenital adrenal hyperplasia (cah) have a predisposition to making extra testosterone. For girls this can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at the time of birth. Girls can also have somewhat masculinized behaviors. The testosterone levels can be lowered by therapy. Boys do not have genital or behavioral issues. ...Read more

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What symptoms does someone with congenital adrenal hyperplasia have?

CAH: This is due to the lack of an enzyme needed for the adrenals to make cortisol and aldosterone. The body then uses the precursors to make androgen (male hormones) instead. Symptoms for girls: deep voice, abnormal menstruation, early appearance of pubic/armpit hairs, genitials looking both male and female...For boys: deep voice, enlarged penis, small testes, early appearance of pubic, armpit hair... ...Read more

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Can you tell me what is congenital adrenal hyperplasia in simple words?

Yes: These people have a gene that makes it hard to make the necessary hormone cortisol, and the molecules get shunted into producing masculinizing hormones instead. The adrenals are big. In mild cases, it simply produces extra body hair in women. In severe cases, a little girl's genitals are ambiguous from birth, or a little boy reaches puberty at a very early age. ...Read more

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What is the definition or description of: congenital adrenal hyperplasia?

What is the definition or description of: congenital adrenal hyperplasia?

See below: It is a collection of genetic conditions that limit your adrenal glands' ability to make certain vital hormones. In most cases of congenital adrenal hyperplasia, the adrenal glands don't produce enough cortisol. The production of two other classes of hormones also may be affected, including mineralocorticoids (for example, aldosterone) and androgens (for example, testosterone). ...Read more

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How can congenital adrenal hyperplasia affect the social life of a person?

Depends on the type: Of enzyme defect and the gender of the patient. Congenital adrenal hyperplasia is a group of disorders that affect the hormones produced by adrenal gland. The disorders affect electrolyte and sex hormones and may cause ambiguous sexual organs in girls. See this site for more information.
http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001448/. ...Read more

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Is it possible that i fight the symptoms of congenital adrenal hyperplasia?

Unclear question: You did not provide any symptoms or signs and it is not feasible to answer the question without examining you and doing some blood tests. Please consult a doctor for an evaluation. ...Read more

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What are the symptoms of congenital adrenal hyperplasia and can I fight them?

Hormone imbalance: Deficiency of 21 hydroxylase enzyme results in reduced synthesis of gluco- and mineralo- corticoids and excess production of male sex hormones. There is not way to "fight" the disease, but it can be treated with glucocorticoids, e.g., predinisolone. The defect causes virilization in girls an pre-mature puberty in boys. ...Read more

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Can you tell me what is congenital adrenal hyperplasia and its effects and cause?

Genetic defect: There is more than one type of inherited enzyme defect that results in lack of normal adrenal hormones and enlargement of the gland. It results in electrolyte abnormalities and defects of sex organs. See this site for more info.
http://www.mayoclinic.com/health/congenital-adrenal-hyperplasia/ds00915. ...Read more

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May I ask what are the effects of late Congenital adrenal hyperplasia medication at 6 years old?

May I ask what are the effects of late Congenital adrenal hyperplasia medication at 6 years old?

Varies: This situation is extremely serious even if the illness is mild. There are various ways of treating it, but you need to discuss this with Junior's physician. I am glad it was diagnosed. ...Read more

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What are symptoms of congenital adrenal hyperplasia in girls?

What are symptoms of congenital adrenal hyperplasia in girls?

It varies: Persons with the most common form of congenital adrenal hyperplasia (cah) have a predisposition to make extra testosterone. For girls can manifest as genitalia that is "masculinized" before birth and therefore "ambiguous" at birth. Some girls can also have "salt wasting". Girls can also have somewhat masculinized behaviors. Testosterone levels can be lowered by therapy. www.caresfoundation.org. ...Read more

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What are the similarities of pcos and non-classical congenital adrenal hyperplasia?

Many similarities: Women with pcos or non-classical cah can have essentially identical symptoms: irregular periods, hirsutism, even virilization, infertility, acne. Both usually have features of metabolic syndrome/insulin resistance. Non-classical cah can have precocious puberty. The test to distinguish the two is a baseline and acth stimulated 17-oh progesterone. An endocrinologist is needed for this situation. ...Read more

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Are metformin 500 mg and spironolactone helpful for pcos and adrenal hyperplasia?

Are metformin 500 mg and spironolactone helpful for pcos and adrenal hyperplasia?

Likely not both: Two different problems, two answers. Spironolactone can be helpful for treating (symptomatically only) unwanted body hair growth with either disease. Metformin is often helpful for women with pcos but has no well established role for treating cah. ...Read more

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How do you prevent congenital adrenal hyperplasia?

Genetic testing: Congenital adrenal hyprplasis is an inherited disorder. Genetic screening can detect persons with the abnormal gene. Prenatal diagnosis can be made. Please consult this site for more information.

http://www.nlm.nih.gov/medlineplus/ency/article/000411.htm. ...Read more

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How to treat congenital adrenal hyperplasia quickly?

?Quickly?: The diagnosis implys a genetic abnormality that will last a lifetime.It can be managed over time with the aid of metabolic disease specialists working in conjunction with your local source of health care. Daily medication & scheduled followup tests and exams will gauge the progress. ...Read more

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What does congenital adrenal hyperplasia cah look like?

What does  congenital adrenal hyperplasia cah look like?

Virilization: In the classic form newborn girls will often have ambiguous looking genitalia because of intrauterine exposure to their own overproduction of androgens. Can't really see it in a newborn boy. In non-classical early pubic hair in both sexes can be presenting feature. As kids grow older other things may warrant checking like recalcitrant acne (both sexes) or irregular periods/hirsutism in girls. ...Read more

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How to treat non-classical congenital adrenal hyperplasia?

How to treat non-classical congenital adrenal hyperplasia?

Male or Female?: This would depend on the age and sex of the patient in addition to the degree of severity. If cortisol response is normal and a male is affected, often times steroid suppression is stopped after puberty. This is more complicated in females who may otherwise suffer from irregular periods, hirsutism, recalcitrant acne. They may need treatment through adulthood. Please discuss with endocrinologist. ...Read more

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Could my son be born with cah congenital adrenal hyperplasia?

Could my son be born with cah congenital adrenal hyperplasia?

Oh, now i know CAH: Previous answer, i thought it meant chronic active hepatitis. Yes, a girl or boy can be born with cong adrenal hyperplasia; this refers to a group of inherited disorders of the adrenal gland, where there is a lack of a hormone needed to make certain steroid hormones. Male sex characteristics may appear earlier than normal. Time for a pediatric endocrinologist, if there is any question of this. ...Read more

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My 9 month old has been diagnosed with congenital adrenal hyperplasia. How was it inherited?

My 9 month old has been diagnosed with congenital adrenal hyperplasia. How was it inherited?

Autosomal recessive: You and the baby's father are both carriers for this disorder. Therefore neither of you actually has it. Please get genetic counseling because your next children will all have a 25% chance of being born with cah. Should your child want children of his/her own, all of them will be carriers. Cah would only happen in your grandchild if your daughter/son's partner is also a carrier or has cah. ...Read more

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Should i be concerned if my 9 month old has been diagnosed with congenital adrenal hyperplasia.?

Yes, but there is: Effective treatment. You should be concerned but know that the disorder can be treated and you should follow your doctor's advice closely. Please read the information on this site for reassurance and advice.
http://www.mayoclinic.com/health/congenital-adrenal-hyperplasia/ds00915. ...Read more