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Doctor insights on: Acidosis In Diabetes

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What is the biochemical mechanism of lactic acidosis in diabetes?

What is the biochemical mechanism of lactic acidosis in diabetes?

Lactic acidosis: Please go online to "www.ncbi.nlm.nih.gov/" and look up lactic acidosis and diabetes. It won't be easy reading but worth a look. You can also go to PubMed and search for lactic acidosis and diabetes. Take your time learning about this. ...Read more

Dr. Quang Nguyen
3,145 doctors shared insights

Diabetes (Definition)

Presistent increased frequency of emptying bladder, urinating, as a symptom of a disease state. 2 types: Mellitus (high blood glucose) & Insipidus (inadequate anti-diuretic hormone). In Diabetes mellitus, the far more common, glucose concentrations are ↑ed due to combination of 8 organ system changes referred to as the "ominous octet" & aggravated by intake of sugars (simple & complex ...Read more


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Is metformin dangerous with diet-induced(not diabetes-induced)ketosis?Like would a ketogenic diet+metf cause metabolic acidosis?(2000mgmet a day btw)

Is metformin dangerous with diet-induced(not diabetes-induced)ketosis?Like would a ketogenic diet+metf cause metabolic acidosis?(2000mgmet a day btw)

Its possible: I have many patients on metformin and in ketosis and its sometimes fine but you must watch out for hypoglycemia. For example if on a regular diet you require metformin but then then go into ketosis (which will severely reduce your' blood sugar) if you keep taking the same dose of metformin you could become hypoglycemic and this needs to be monitored by your' doctor. ...Read more

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How long can a person live with symptoms of diabetes before diagnosis?

How long can a person live with symptoms of diabetes before diagnosis?

Depends: On Type of diabetes and severity of symptoms. Type 1 diabetes is usually profoundly symptomatic and rapidly progresses to dehydration, acidosis and death if not treated promptly. Type 2 diabetes can be symptomatic for months, if not years before it comes to medical attention. Thanks for trusting HealthTap! ...Read more

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What sort of problem is acidosis of the blood?

What sort of problem is acidosis of the blood?

Let's get specific: In the absence of obvious disease / poisoning, perhaps you have been told you have metabolic acidosis (complicates a host of illnesses and especially some of the diabetes / metabolic syndrome pills) or renal tubular acidosis (mild-to-serious problem handling bicarbonate.) some charlatans diagnose "blood acidosis" without basis. ...Read more

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How long before a type 1 diabetic goes into DKE if they don't know they have diabetes? My husband found out he had diabetes at 22 only because of DKE?

How long before a type 1 diabetic goes into DKE if they don't know they have diabetes? My husband found out he had diabetes at 22 only because of DKE?

Highly variable: Hi. It's DKA (Diabetic KetoAcidosis), not DKE. How long it takes to go into DKA is highly variable and generally gets longer the older the person is at age of diagnosis. Most diabetics are diagnosed before onset of DKA these days simply because of seeing doctors and ease of lab testing. Once they've been type 1 for awhile and have little or no beta cell function remaining, it can happen faster. ...Read more

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Can diabetes be fatal?

Can diabetes be fatal?

Most certainly: Diabetes is a multi system disease and can be lethal in many ways. The sugar can get way out of control and a condition called keto-acidosis can be fatal. Diabetes affects blood vessels, kidneys, eyes, the brain and the heart and damage to any of these can lead to severe illness and sometimes death. Control is best in the hands of a good endocrinologist. ...Read more

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What is diabetic keto acidosis?

What is diabetic keto acidosis?

DKA: A metabolic emergency for patients primarily with type 1 diabetes, DKA symptoms include those of high blood sugars initially. As the ketones build up, patients may have a fruity odor on the breath, get abdominal pain & vomit. Because they're already urinating a lot, dehydration can get bad. Some may breathe fast, get headaches, have altered consciousness. Without proper treatment, death imminent. ...Read more

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What sort of metabolism disorders can diabetes cause in the rest of your body?

What sort of metabolism disorders can diabetes cause in the rest of your body?

Various conditions: Severe uncontrolled diabetes can cause several metabolic problems. The most dire is diabetic ketoacidosis (dka), which is more common in patients who are Insulin deficient. Dka is a severe form of metabolic acidosis that can lead to multiple organ failure. Very high glucoses can also cause high triglycerides, a disorder of fatty particle metabolism that may lead to pancreatitis and heart disease. ...Read more

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What are the tests done to diagnose diabetes type 1?

What are the tests done to diagnose diabetes type 1?

Blood sugar: Urinalysis and Blood sugar can be diagnostic. Blood chemistries can also indicate the level of acidosis if the condition has progressed significantly. ...Read more

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Need expert help here. What are some ways of treating metabolic acidosis?

Correct the problem: Metabolic acidosis from renal tubular disease is treated with bicarbonate, lactic acidosis requires treating the source of the acid production, ketoacidosis requires relief of the diabetes or starvation with Insulin and carbohydrates. The source of the imbalance for acidosis must be identified and corrected. ...Read more

Acidosis (Definition)

Normally our body chemistry is kept in a narrow range, and in particular the amount of acid in the body is kept within a narrow range. The amount of acid is measured by a value called the ph. It is normally a value between 7.35 and 7.45, values below 7.35 are considered to be "acidotic" a patient with this value of the blood chemistry ...Read more


Dr. Quang Nguyen
2,020 doctors shared insights

Diabetes Type 2 (Definition)

Diabetes Mellitus type 2, or adult onset diabetes, is a condition that is caused by insulin resistance. This means that the muscle and fat cells of the body do not take up blood glucose, leaving a high blood glucose. Some type 2 ...Read more