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Doctor insights on: Acetylcholinesterase Deficiency

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What is acetylcholinesterase inhibitor?

What is acetylcholinesterase inhibitor?

Blocks the enzyme: Mutliple drugs are available to block the effects of this enzyme which breaks down acetylcholine - essential for muscle movement along with many other functions. Used for myasthenia gravis, alzheimers, glaucoma, etc. ...Read more

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What compounds increase acetylcholinesterase activity?

Why do you ask?: Or ... "What are Organophosphates?" if you're playing Jeopardy. ...Read more

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What are normal results for amniotic acetylcholinesterase?

What are normal results for amniotic acetylcholinesterase?

Negative.: Acetylcholinesterase should not be detectable in the normal amniotic fluid. Its presence is pathognomonic of open neural tube defects and/or other open lesions of the fetus with exposure of neural elements such as teratomas and amniotic band sequences. ...Read more

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Do you know if acetylcholinesterase is a multi-substrate enzyme?

Do you know if acetylcholinesterase is a multi-substrate enzyme?

Enzymolology: That's an interesting question. Many enzymes are capable of processing more than one substrate, but they are not very efficient with multiple substrates. A good example is alcohol dehydrogenase. Acetylcholinesterase is essentially a "one-substrate" enzyme based on its biochemical properties. ...Read more

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How does huperzine differ from other acetylcholinesterase inhibitors?

How does huperzine differ from other acetylcholinesterase inhibitors?

Drug out of China: Huperzine a might have some benefit similar to drugs such as donepezil, rivastigmine, or galantamine, (galantamine hydrobromide) as it too, is a cholinesterase inhibitor. Has received hype in the alternative literature, due to lack of branding and commercial ownership, but it is unlikely to be any better than the above prescription meds. Do not waste money pursuing the "chinese aricept". ...Read more

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A drug to reduce the activity of acetylcholinesterase.?

A drug to reduce the activity of acetylcholinesterase.?

Enzyme Blocker: Mutliple drugs are available to block the effects of this enzyme which breaks down acetylcholine - essential for muscle movement along with many other functions. Used for myasthenia gravis, alzheimers, glaucoma, etc. Drugs such as edrophonium, neostigmine , physostigmine, pyridostigmine, etc. ...Read more

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What is the name of the disease when the acetylcholinesterase does not work?

What is the name of the disease when the acetylcholinesterase does not work?

Pseudochol deficient: Pseudocholinesterase deficiency is an inherited enzyme abnormality that results in abnormally slow breakdown of drugs such as succinylcholine (typically used during anesthesia for surgery). The drug thus takes lower to break down and causes a longer than expected effect - sometimes lasting hours as opposed to minutes. ...Read more

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Please help! what is the name of the disease when the acetylcholinesterase does not function?

Please help! what is the name of the disease when the acetylcholinesterase does not function?

Here are some: Perhaps you are thinking of Myasthenia Gravis, where the acetylcholine fails due to immune damage of the neuromuscular junction, but botulism and black widow spider bites also affect acetylcholine transmission, and this chemical drops in Alzheimer's and Parkinsonian dementias. ...Read more

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If acetylcholinesterase is not present to remove acetylcholine, the muscle is in contraction. What is the name of the disorder/disease?

If acetylcholinesterase is not present to remove acetylcholine, the muscle is in contraction. What is the name of the disorder/disease?

Acetylcholinesterase: is always present. Acetylcholine doesn't just cause muscle contraction; it's essential in the CNS as well. You can't have absence in one place & presence in the other. Our bodies don't work that way. An absence of acetylcholinesterase is not compatible with life. ...Read more