Doctor insights on:
Acetylcholine Receptor Blocking Ab
Tested for acetylcholine receptor ab panel; both binding and blocking were 0, but modulating came back at 10. Does this mean I have myasthenia gravis?
AchRAntibodies: Binding antibodies are the most sensitive--they are positive in over 80% of ms patients. Blocking antibodies are positive in about half. Modulating antibodies alone don't support the diagnosis and have a lot oof false positives. In summary the achreceptor antibody panel does not suggest that ou have ms>. ...Read moreSee 2 more doctor answers
An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more
I failed my qsart test what is the next step and what could this mean? Acetylcholine receptor ab 0.00 nmol/l <=0.02 12/12/2012
and my antibody norma
QSART: Quantitative sudomotor autonomic reflex testing (qsart) is used to diagnose: painful small fiber neuropathy when nerve conduction test results are normal; disturbances of the autonomic nervous system, which controls the sweat glands, heart, gastrointestinal tract, other organs, and blood pressure; complex regional pain syndrome or reflex sympathetic dystrophy. A discussion with ur neurologist next. ...Read more
Neuromusculat ransmi: Acetylcholine is an import neuromuscular transmitter that controls muscle functions and bodily and organ movements inside. So using antagonists can block these processes and cause trouble especially with the function of our smooth muscles of the bowel(constipation)bladder(urine retention) and eyes(blurred vision). ...Read more
What other diseases can give the same symptoms as systemic myasthenia gravis when antibodies against the acetylcholine receptor are negative?
different things: Agonists stimulate receptors while antagonists inhibit them. Most often we use the antagonist drugs in treating different diseases. However, those conditions that decrease sputum, sweat or tear production are sometimes treated with an agonist . Pilocarpine (an agonist) is used to treat glaucoma but by a different mechanism as mentioned above. ...Read more
Can you tell me in myasthenia gravis why do you give an acetylcholine esterase inhibitor instead of a direct receptor agonist?
I read that there are nmda-like receptors in the epidermis. Would the anti-nmda ab test show antibodies to receptors in skin?
No : Classically the nmda receptors are in the nervous system and associated with neurologic disease. There are tiny nerve fibers in the skin that have the receptor, not the skin itself, what importance this has in human disease is unknown, but some medical scientists think drugs which act on them may be useful in pain control some day. ...Read more
Possible: You may be feeling decreased motivation due to the illness you are being treated for, or as a side effect of the medication. Side effects can wear off so if not too detrimental, give it some time. It is important to always let your treating physician know how you are feeling. Take good care of yourself while you heal. ...Read more
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