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Why do you ask?: Or ... "What are Organophosphates?" if you're playing Jeopardy. ...Read more
Yes: Yes, only dopaminergic neurons release dopamine, but there are several dopaminergic pathways in the brain. Dopaminergic neurons in midbrain are the main source of Dopamine in the mammalian cns. Losing these is associated with parkinson's disease. Dopamine neurons are involved with voluntary movement and other behavioral processes such as mood, reward, addiction, psychosis, and stress. ...Read more
Atomoxetine inhibits serotonin transporter, dopamine transporter and naroephinephrine. What does inhibit mean?
Strattera (atomoxetine): Inhibition is the opposite of stimulation, so the effectiveness is reduced. ...Read more
Yes. Great Question!: The Amino Acid glutamate plays a central role in nitrogen metabolism & participates in multiple biochemical pathways. Disease examples: autoantibodies to the glutamate receptor kill neurons via activation of the receptor ion channel. Anti-nmda receptor encephalitis is a treatment-responsive inflammatory encephalopathic autoimmune disease associated with anti-nmda receptor antibodies. ...Read more
Not safe: GABA antagonists are not routinely prescribed for GABA A receptor upregulation. The main one flumazenil (clonazepam) is used for overdoses from benzodiazepines in an ER setting. It may cause withdrawal seizures. Your best bet is to detox and enter a drug tx program for alcohol or sedative-hypnotic dependence issues. ...Read more
Which glutamate receptor(s) are affected negatively by monosodium glutamate: ampa, nmda, and/or kainate?
Most newer ones: Most of the newer antidepressant medications affect specific neurotransmitters. Each does it slightly differently, accounting for the different response rates amongst them. The SSRI's primarily increase serotonin, the SNRI's both serotonin and norepinephrine, and buproprion mostly norepinephrine alone, and Brintellix affects many of them in different ways and in different places in the brain. ...Read more
Can autoantibodies against glutamine synthetase and/or glutamate dehydrogenase cause glutamate metabolism disorders?
Still searching: Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. I am unble to find references in my search so far as to autoantibodies to these but see comment. ...Read more
Why does acetylcholine, an inhibitory neurotransmitter, cause the adrenal glands to release stimulatory hormones?
Not correct: Hi. Acetyl choline (ACh) is not an inhibitory neurotransmitter. The sympathetic nervous system uses ACh as the neurotransmitter in the sympathetic ganglia (the 1st synapse outside the CNS). Usually that's from one neuron to another, but in the adrenal medulla, the cells are really the second neuron, but they release their contents (catecholamines) into the blood, not onto an organ (like the heart) ...Read moreSee 1 more doctor answer
NO: In general, MAO inhibitors refer to specific prescription antidepressant drugs & are highly regulated. Many foods & herbs have mild MAO inhibiting actions, such as carrots, chocolate, coffee, ginger, grape & onions,but these effects are not clinically significant & they don't need to be avoided if on a med that interacts with MAO inhibitors: http://www.botanical-online.com/english/vegetalmaois.htm ...Read more
Excitatory: Histamine is actually classified as an excitatory neurotransmitter in the brain responsible for the sleep wake cycle. Too much of it can keep you awake. That is why it is used in many commercial sleep aides seen with the letters "pm" attached to some kind of pain killer. A common side-effect of a histamine blocker like Diphenhydramine (benadryl) is drowsiness. ...Read more
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