Doctor insights on:
Acetaminophen Metabolism Pathway
What is the pathway tylenol (acetaminophen) takes through the body when administered through the rectum?
Tylenol (acetaminophen) absorpion: hello ~ odd but interesting question. EXACTLY THE SAME ROUTE AS TAKING IT ORALLY, (or we wouldnt suggest taking it that way.) The rectal mucus membrane is exactly the same histologically as the mouth, so it gets absorbed thru the mmembrane, into the rectal veins into the internal iliac, into the coeliac vein and then the splenic vein AND portal v to liver. Metab in liver!Out in bile and duodenum.. ...Read more
What to do if I can't understand the pathway..so anyone can give any of metabolism bilirubin explanation?
Get help: The porphyria synthesis and breakdown pathways are elementary if you understand organic chemistry and its application to general metabolism, incomprehensible if you do not. Nobody here is going to be able to tell you anything more. Perhaps there has been a problem with sequencing the topics. ...Read more
What is the pathway and role of vitamin B12 in metabolism/catabolism of phenylalanine and tyrosine? Thank you.
Don't do it again: This won't hurt or kill you, but you do need to show this helpful drug the respect it deserves. It's important to space the doses out so that you don't get sick. Up to 4000 mg/day is fine but you don't want to take even this much all at once -- you might overload the enzyme that processes it by the normal pathway. ...Read moreSee 1 more doctor answer