Doctor insights on:
Ace Inhibitors Vs Calcium Blockers
Is unstable angina controlled by just a beta blocker? Or does it need a combination of beta, ace-inhibitors, calcium blockers, or other?
Are beta blockers alone effective in vasodilation around the heart or is combination therapy neccessary, i.e. ace-inhibitors, calcium blockers, etc?
BB not vasodilators:
The medicines you mention act in three different ways and depending in what you are trying to achieve they can be used separately or together for a variety of conditions, from hypertension to even heart failure (although cal antagonists not recommended for the latter).
But beta blockers are not vasodilators
The calcium: Channel blocker might if your hr is too low or the combination if your HTN is overtreated. ...Read more
Why is it necessary that white patients should be started with an ACE inhibitor or beta blocker while blacks with calcium channel blocker/diuretics?
Not usual: Calcium channel blockers are not commonly associated with heart burn but in a given individual, anything is possible. In these circumstances, it's usually a good idea to temporarily stop the medicine until you're feeling better and then restart it. If the heartburn comes right back, you may have to switch to a different drug. ...Read more
How to treat ankle edema as a side effect of amlodipine plus if the hypertensive pt. Had been changed frm ACE inhibitor to a calcium channel blocker?
I have rising potassium on lisinopril. Switched to amlodipine starting tmrw. What can I expect from change of ACE inhibitor to calcium channel blocker?
How long do hypertension medications (diuretics vs ACE inhibitors vs Ca channel blockers vs etc.) take to achieve full effect?
Hours to weeks: The oral medications for treating high blood pressure start to work as soon as they are absorbed and the full effect of a single dose occurs within hours. Most blood pressure drugs sustain the reduction in BP for 24 hours so they can be taken once daily. When starting medication or changing dose there may be some further blood pressure reduction over the next several weeks. ...Read more
Generally, how potent is clonidine when compared to other hypertensive medications, such as beta blockers and ACE inhibitors? Or, is it so individual?
Hypertension: Current 1st line medication for hypertension or high blood pressure is a thiazide diuretic (water pill) like hctz (hydrochlorothiazide) unless you have a compelling reason eg diabetes, heart disease, kidney disease, etc for something else. Clonidine is far down list. It works but all BP meds work. Down side of Clonidine is rebound hypertension if you forget to take dose. Some find it sedating. Potency depends upon dose. ...Read more
Block aldosterone: The primary mechanism of action of a ace inhibitors is to interrupt the renin angiotensin system. One of the results is reduced aldosterone synthesis. Aldosterone is an important hormone responsible for regulating potassium excretion by the kidney. Thus blocking aldosterone reduces the capacity of the kidney to excrete potassium. ...Read more
ACE: ACE inhibitors are BP treatment but otherwise don't treat CVA specifically ...Read more
You can: You can, in fact they make combination pills that contain both. ...Read more
Why are ACE inhibitors particularly prescribed for persons with left ventricular contractile dysfunction?
No Difference: Ace and arb both are used to treat hypertension by similar mechanisms. They decrease blood flow to part of the kidney that causes an overall decrease in total blood pressure. The only difference is that with an ace you can develop a persistent dry cough. Once this occurs, you have an allergy to the ace. The arb treats the BP without the cough. ...Read more
Heart and kidney: Ace inhibitors are blood pressure medications used for blood pressure treatment. They also have effects independent of the blood pressure effect on the heart, particularly for people with heart failure, and on the kidneys, particulaly for people who have diabetic-induced kidney disease with protein in the urine. ...Read more
No: There is a common misconception that calm people don't have hypertension and treating antihypertensives will calm people. Overall that is not the case. There may be one exception. Beta blockers block adrenaline which can make one feel calmer. Acei other antihypertensives usually do not result in people feeling calmer. ...Read more
Ace vs arb: They are drugs which block functions at different points in the same pathway. Ace blocks an enzyme and arb blocks a receptor, their effects are similar. It's something like either cutting a wire to a spark plug or damaging the plug itself. Either way you don't get a spark. ...Read more
Not in 400 letters!: This is too big of a question and cannot be answered in such a short format. You could ask something more specific so that we can help you. ...Read more
If it is not uncommon for ACE inhibitors to produce an annoying cough, why not prescribe arbs from the get go? Are they generally less effective?
Possibly: In susceptible individuals, ace inhibitors can cause angioedema. This typically involves the lips or the face, but can affect any part of the skin and internal organs such as the intestines. It would be unusual for acei to cause angioedema of only the intestines, however. A thorough evaluation by an allergist can help you sort this out. ...Read more
ACEs vs diuretics: They are not. Diuretics are, on the average much better and less expensive than ACEs. Especially if you are African American. ...Read more