Doctor insights on:
Accutane And Birth Defects
It WILL cause defect: "The baseline population risk of malformations is 3-5%, but it increases to almost 30% in women exposed to isotretinoin during the first trimester of pregnancy." see http://www.ncbi.nlm.nih.gov/pubmed/19961047 Many are profound, horrible defects--absent ears, tiny brain, deafness and blindness. Effects may occur many months after a woman ceases taking it. ...Read moreSee 1 more doctor answer
Accutane: There are multiple birth defects associated with intrauterine exposure to accutane. There is a certain critical time in the pregnancy where the greatest amount of potential harm can occur. Genetic counseling is strongly recommended to determine what possible effects Accutane exposure could have. ...Read more
Does roaccutane (accutane) medication for acne cause birth defects in a child if the father is taking it, not the mother?
Accutane: Accutane is known to cause human fetal abnormalities. While a woman is on Accutane she should use one or two reliable forms of contraception to prevent conception. Accutane stays in the body for a long time, so after stopping Accutane contraception must be continued for at least 3 months. ...Read moreSee 2 more doctor answers
I took two Accutane pills on february 22 and 23. Each pill is 5 mg. I conceived on may 30. Should I be worried that my baby will have birth defect?
No: The Accutane should be metabolized and out of your system by the time you conceived. Medical guidelines allow for discontinuation of birth control 30 dyas after the last dose at which point the risk is minimal related to accutane. Most of the birth defects associated with Accutane are associated with its use during pregnancy (after implantation of the embryo). Given your timing, minimal risk. ...Read moreSee 1 more doctor answer
Could a male's 9 mo Accutane use at age 16 years cause his unborn baby's diagnosis of congenital vsd 10 years later? Or other birth defects?
Unrelated: Any sperm that might be affected during use are long gone 9 years later.We have no data suggesting males use of Accutane relates sperm or causes any birth defect. The medication has a direct toxic effect to an embryo if consumed by the mother during pregnancy. Congenital vsd is one of the most common heart related defects & has a broad genetic basis & some recurrence risk. ...Read moreSee 2 more doctor answers
How does Accutane not affect your fertility after? It's so serious in causing birth defects while on the drug and messes up hormones, how is it safe?
Who says it's safe?: It is one of the more toxic drugs, and the only reason we use it is because for some people, the pain of living with severe acne makes its risks worthwhile. Accutane acts on rapidly growing tissues, which is why it is contraindicated in pregnancy; but it does not appear to be as toxic to ovaries and eggs as it is to an embryo or a fetus. ...Read more
Expect to: This is not a med to try to cheat on. I never prescribe it myself, because of the risks involved.I believe the manufacturer requires women to sign off on the warnings about pregnancy as part of their requirement for providing the drug.They also suggest you use two forms of birth control if sexually active. ...Read moreSee 1 more doctor answer
Pretty limited: Some birth defects such as fetal alcohol syndrome, defects associated with use of Accutane during pregnancy, and neural tube defect associated with Folic Acid deficiency are some examples whose occurrence can be minimized at least if not totally preventable. ...Read moreSee 1 more doctor answer
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