Doctor insights on:
Ac And Taxol Chemotherapy
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?
There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more
Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more
Modestly well: Your doctor can address this question better as I do not have details of your tumor sites and bulk of metastases. In general, chemo for metastatic Colon cancer is palliative which means it can be treated and kept under check for months/years but often not curable unless the tumor is amenable to surgical excision following a partial tumor regression with chemotherapy. Good luck. ...Read more
Not a standard treat: Cytoxan (cyclophosphamide) and 5-fu jused to be used as first line chemo for breast cancer, but there are much more effacious drugs available now. I would not use these drugs now as first line treatment fofr anything except in special circumstances. ...Read moreSee 1 more doctor answer
Diagnoged with cutaneous tcell lymphoma nhl.Treated with eletron beam.Interferon, gemcitabine, anthracycline, etoposide, procarbazine.Nodules over body .?
Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug,protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more
Liver and peritoneal mets for mcrc patient . What is approx survival
With chemo , oxyplatin and raltitrexed ?
We can not guess: We can not tell you what the approx. survival as we do not have all the information to make a comment on the approx. survival You should discuss with your treating Oncologist There are second and third line treatments as well which may change the course ...Read more
Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?
I have triple negative stage 3 breast cancer. Ac followed by t. Neulasta (pegfilgrastim) for ac....Is it routine to continue neulasta (pegfilgrastim) for t treatments?
Neulasta (pegfilgrastim): For ac regimen dose dense (every 2 weeks, we recommend neulasta). After that i usually give Taxol (also called paclitaxel) weekly x 12 weeks and Neulasta (pegfilgrastim) is not used for weekly regimen. Some oncologists prefer Taxol every 3 weeks x 4 doses (big dose taxol), than it can be used. Weekly regimen have robust data and is well tolerated and we can avoid side effects of Neulasta (pegfilgrastim) (which can be rough). ...Read moreSee 1 more doctor answer
Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read moreSee 1 more doctor answer
No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read moreSee 1 more doctor answer
Maybe: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given. Some long term effects is neuropathy (numbness fingers) and hearing loss but these tend to be due to cumulative dose. ...Read more
Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?
Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more
What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin ( GEMOX) ?
Modest side effects: Gemcitabine is a well tolerated chemo drug. It can cause some decrease in blood counts, so monitor your CBC periodically(something your oncologist will discuss and do it for you). Oxaliplatin has some additional side Effects like nausea and neuropathy, yet these are manageable by any good oncologist. So I would advice you to proceed with chemo and wait to worry if you have any side effects. ...Read more
Husband is being put on carboplatin/arbraxane for 3b squamous nsclc, after taxol (paclitaxel) reaction. Concurrent radation therapy. Is this an effective plan?
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