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Doctor insights on: Ac And Taxol Chemotherapy

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Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Ciii  ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin.  In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read more

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Dr. Devon Webster
975 doctors shared insights

Chemotherapy (Definition)

The term chemotherapy typically is used to describe using chemicals to treat ...Read more


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Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?

Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or  rituximab+bendamustine?

There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft. ...Read more

Dr. Craig Lum Dr. Lum
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What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Dr. Craig Lum Dr. Lum
1 doctor agreed:
What can prognosis b like for metastic colon cancer that chemotherapy oxyplatin and raltitrexed ?

Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more

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How well Does chemotherpay oxyplatin and raltitrexed work for met colon cancer ?

How well
Does chemotherpay oxyplatin and raltitrexed work for met colon cancer ?

Modestly well: Your doctor can address this question better as I do not have details of your tumor sites and bulk of metastases. In general, chemo for metastatic Colon cancer is palliative which means it can be treated and kept under check for months/years but often not curable unless the tumor is amenable to surgical excision following a partial tumor regression with chemotherapy. Good luck. ...Read more

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For what cancers does chemotherapy with cytoxan, (cyclophosphamide) 5-fu help?

For what cancers does chemotherapy with cytoxan, (cyclophosphamide) 5-fu help?

Not a standard treat: Cytoxan (cyclophosphamide) and 5-fu jused to be used as first line chemo for breast cancer, but there are much more effacious drugs available now. I would not use these drugs now as first line treatment fofr anything except in special circumstances. ...Read more

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Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug,protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more

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Liver and peritoneal mets for mcrc patient . What is approx survival With chemo , oxyplatin and raltitrexed ?

Liver and peritoneal mets for mcrc patient . What is approx survival
With chemo , oxyplatin and raltitrexed ?

We can not guess: We can not tell you what the approx. survival as we do not have all the information to make a comment on the approx. survival You should discuss with your treating Oncologist There are second and third line treatments as well which may change the course ...Read more

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Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?

Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?

Chemotherapy for SS: I would potentially seek out an opinion from the mayo clinic oncology department who are not very far north of you. I can help set that up for you. Please contact me at David.stockman@orthopath.com ...Read more

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I have triple negative stage 3 breast cancer. Ac followed by t. Neulasta (pegfilgrastim) for ac....Is it routine to continue neulasta (pegfilgrastim) for t treatments?

I have triple negative stage 3 breast cancer. Ac followed by t. Neulasta (pegfilgrastim) for ac....Is it routine to continue neulasta (pegfilgrastim) for t treatments?

Neulasta (pegfilgrastim): For ac regimen dose dense (every 2 weeks, we recommend neulasta). After that i usually give Taxol (also called paclitaxel) weekly x 12 weeks and Neulasta (pegfilgrastim) is not used for weekly regimen. Some oncologists prefer Taxol every 3 weeks x 4 doses (big dose taxol), than it can be used. Weekly regimen have robust data and is well tolerated and we can avoid side effects of Neulasta (pegfilgrastim) (which can be rough). ...Read more

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What is the role of Taxol (paclitaxel) in chemotherapy?

What is the role of Taxol (paclitaxel) in chemotherapy?

Kills cancer cells!: Taxol (paclitaxel) works by preventing cancer cells from reproducing themselves. In the picture you can see green "microtubules" that are pulling a cancer cell apart into two daughter cells. Taxol blocks microtubules, preventing them from being able to pull the cancer cell into two daughter cells. The cancer cell gets stuck trying to divide, and it dies. Taxol works for many cancer types. ...Read more

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Is neulasta (pegfilgrastim) needed with weekly taxol?

Is neulasta (pegfilgrastim) needed with weekly taxol?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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How are chemotherapy and radiation therapy different?

How are chemotherapy and radiation therapy different?

X-rays versus drugs: Radiation is a beam of energy that comes from aimable machines through the air. Chemotherapy is drugs given into veins or by oral pills. So one goes through air and the other in the blood. ...Read more

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Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

YES DOUBLET: Taxotere (docetaxel) + carboplatin: is a combination regimen used in certain cancers like lung, ovary and breast (with herceptin). ...Read more

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Any bad effects with the chemo drug cisplatin?

Any bad effects with the chemo drug cisplatin?

Maybe: Cisplatin - like any other chemotherapy drug has potential side effects. The most common is nausea but you can take anti nausea medication. It may cause hair loss and decrease in white blood cell counts. Kidney function should be monitored and IV fluids given. Some long term effects is neuropathy (numbness fingers) and hearing loss but these tend to be due to cumulative dose. ...Read more

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Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?

Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more

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What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin ( GEMOX) ?

What are typical side effects of liver cancer chemo therapy consisting of Gemcitabine + Oxaliplatin ( GEMOX) ?

Modest side effects: Gemcitabine is a well tolerated chemo drug. It can cause some decrease in blood counts, so monitor your CBC periodically(something your oncologist will discuss and do it for you). Oxaliplatin has some additional side Effects like nausea and neuropathy, yet these are manageable by any good oncologist. So I would advice you to proceed with chemo and wait to worry if you have any side effects. ...Read more

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Husband is being put on carboplatin/arbraxane for 3b squamous nsclc, after taxol (paclitaxel) reaction. Concurrent radation therapy. Is this an effective plan?

Husband is being put on carboplatin/arbraxane for 3b squamous nsclc, after taxol (paclitaxel) reaction.  Concurrent radation therapy.  Is this an effective plan?

Yes it is!: This is the current recommended chemotherapy(along with concurrent radiotherapy) treatment plan. Hopefully it should work well. But it will take 6-8 weeks to see the full benefit. ...Read more