Doctor insights on:
Abraxane And Avastin
Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more
I am on Abraxane. Tumor Markers started climbing after two months. Dr. Wants to add Avastin (bevacizumab). Is this a good option? Mets to abdomen, bones & Liver.
Not a good idea: Rising tumor markers often predict tumor progression. But this is soft evidence. A more definitive way to confirm lack of response (progression) is by means of repeating Imaging studies (like X-rays/CT scan or PET scan) and compare them with prior study. If the tumor size has increased, then Abraxane is no longer useful for you. Treatment should be changed. Adding Avastin (bevacizumab) would not help the situati ...Read more
Black box warning?: Abraxane is a powerful drug for the treatment of some cancers. Like most chemotherapy meds, it can have serious side effects. See this description of how and when to use it, and when not to, including "Black Box warnings" here. Https://medicalpolicies. Amerigroup. Com/medicalpolicies/guidelines/gl_pw_c189660.htm ...Read more
Avoid it, if it is p: Avastin (bevacizumab) causes interference in wound healing. So it is best to stop Avastin (bevacizumab) if you need to undergo surgery. It takes 4 to 6 weeks for the Avastin (bevacizumab) effects to go away after the last dose used. Then it is safer to do surgery. Your oncologist as well as your surgeon can/will guide you in this regard, if you have not already been told about it. ...Read more
Stops angiogenesis: Avastin (bevacizumab), and was the first commercially available angiogenesis inhibitor. Its main action is the inhibition of the function of a natural protein called vascular endothelial growth factor (vegf) that stimulates new blood vessel formation. Because most malignant tumors are highly dependant on angiogenesis to obtain a blood supply and nutrients Avastin can stop or delay growth. ...Read moreSee 1 more doctor answer
Yes: Http://www. Nlm. Nih. Gov/medlineplus/druginfo/meds/a607001.html.Get a more detailed answer ›
My sister was diagnosed with atypical meningiomanow taking avastin (bevacizumab) what is her survival rate?
Good: Meningiomas are usually benign tumors with excellent prognosis. Symptoms depends on the location of tumor. Atypical meningioma is more concerning and it is in a spectrum (worse than benign but better than malignant meningioma). The idea is to see the rate of growth, slow it if possible. If progressing, surgery, radiosurgery, or traditional radiation or combination of above are possible options. ...Read moreSee 3 more doctor answers
Bevacizumab injectio: See: http://www. Drugs. Com/sfx/bevacizumab-side-effects. HtmlGet a more detailed answer ›
No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf. ...Read moreSee 2 more doctor answers
It doesn't (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf. ...Read moreSee 1 more doctor answer
Different: Xeloda is oral chemotherapy while Avastin (bevacizumab) is a monoclonal antibody targeting vascular growth factor. Bevacizumab (avastin) is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor. It also helps with chemo by allowing entry into tumor microvascular structures while Xeloda helps to inhibit DNA synthesis ...Read more
Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more