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Doctor insights on: Abraxane And Avastin

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Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more

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I am on Abraxane. Tumor Markers started climbing after two months. Dr. Wants to add Avastin (bevacizumab). Is this a good option? Mets to abdomen, bones & Liver.

I am on Abraxane.  Tumor Markers started climbing after two months.  Dr. Wants to add Avastin (bevacizumab).  Is this a good option? Mets to abdomen, bones & Liver.

Not a good idea: Rising tumor markers often predict tumor progression. But this is soft evidence. A more definitive way to confirm lack of response(progression) is by means of repeating Imaging studies(like X-rays/CT scan or PET scan) and compare them with prior study. If the tumor size has increased, then Abraxane is no longer useful for you. Treatment should be changed . Adding Avastin (bevacizumab) would not help the situati ...Read more

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Can you have surgery while taking Avastin (bevacizumab)?

Can you have surgery while taking Avastin (bevacizumab)?

Avoid it, if it is p: Avastin (bevacizumab) causes interference in wound healing. So it is best to stop Avastin (bevacizumab) if you need to undergo surgery. It takes 4 to 6 weeks for the Avastin (bevacizumab) effects to go away after the last dose used.. Then it is safer to do surgery. Your oncologist as well as your surgeon can/will guide you in this regard, if you have not already been told about it. ...Read more

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What affect does avastin (bevacizumab) have on fertility?

What affect does avastin (bevacizumab) have on fertility?

Possible menopause: Avastin (bevacizumab) is used to treat certain advanced cancers. It may cause ovarian failure (induced menopause), up to 34 percent of women in one study. However, this will reverse in 1/5 of women once Avastin is stopped. ...Read more

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I need some information about the mechanism of avastin (bevacizumab) on the body..

I need some information about the mechanism of avastin (bevacizumab) on the body..

Stops angiogenesis : Avastin (bevacizumab), and was the first commercially available angiogenesis inhibitor. Its main action is the inhibition of the function of a natural protein called vascular endothelial growth factor (vegf) that stimulates new blood vessel formation. Because most malignant tumors are highly dependant on angiogenesis to obtain a blood supply and nutrients Avastin can stop or delay growth. ...Read more

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What is the success of avastin (bevacizumab) for treating glioblastoma? Does it work?

What is the success of avastin (bevacizumab) for treating glioblastoma? Does it work?

Marginal: It is primarily being used to treat recurrent malignant gliomas . The latest results with its use as a frontline treatment for malignant glioma show no real benefit over the current conventional regimen using radiation therapy and chemotherapy with temodar (temozolomide). ...Read more