Top
20
Doctor insights on: Abraxane And Avastin

Share
1

1
Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Can Abraxane and Avastin (bevacizumab) be used for treating ovarian cancer?

Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more

2

2
I am on Abraxane. Tumor Markers started climbing after two months. Dr. Wants to add Avastin (bevacizumab). Is this a good option? Mets to abdomen, bones & Liver.

I am on Abraxane. Tumor Markers started climbing after two months. Dr. Wants to add Avastin (bevacizumab). Is this a good option? Mets to abdomen, bones & Liver.

Not a good idea: Rising tumor markers often predict tumor progression. But this is soft evidence. A more definitive way to confirm lack of response (progression) is by means of repeating Imaging studies (like X-rays/CT scan or PET scan) and compare them with prior study. If the tumor size has increased, then Abraxane is no longer useful for you. Treatment should be changed. Adding Avastin (bevacizumab) would not help the situati ...Read more

3

3
What information is on the Abraxane label?

What information is on the Abraxane label?

Black box warning?: Abraxane is a powerful drug for the treatment of some cancers. Like most chemotherapy meds, it can have serious side effects. See this description of how and when to use it, and when not to, including "Black Box warnings" here. Https://medicalpolicies. Amerigroup. Com/medicalpolicies/guidelines/gl_pw_c189660.htm ...Read more

7

7
Can you have surgery while taking Avastin (bevacizumab)?

Can you have surgery while taking Avastin (bevacizumab)?

Avoid it, if it is p: Avastin (bevacizumab) causes interference in wound healing. So it is best to stop Avastin (bevacizumab) if you need to undergo surgery. It takes 4 to 6 weeks for the Avastin (bevacizumab) effects to go away after the last dose used. Then it is safer to do surgery. Your oncologist as well as your surgeon can/will guide you in this regard, if you have not already been told about it. ...Read more

8

8
What affect does avastin (bevacizumab) have on fertility?

What affect does avastin (bevacizumab) have on fertility?

Possible menopause: Avastin (bevacizumab) is used to treat certain advanced cancers. It may cause ovarian failure (induced menopause), up to 34 percent of women in one study. However, this will reverse in 1/5 of women once Avastin is stopped. ...Read more

9

9
I need some information about the mechanism of avastin (bevacizumab) on the body..

I need some information about the mechanism of avastin (bevacizumab) on the body..

Stops angiogenesis: Avastin (bevacizumab), and was the first commercially available angiogenesis inhibitor. Its main action is the inhibition of the function of a natural protein called vascular endothelial growth factor (vegf) that stimulates new blood vessel formation. Because most malignant tumors are highly dependant on angiogenesis to obtain a blood supply and nutrients Avastin can stop or delay growth. ...Read more

See 1 more doctor answer
10

10
What is the success of avastin (bevacizumab) for treating glioblastoma? Does it work?

What is the success of avastin (bevacizumab) for treating glioblastoma? Does it work?

Marginal: It is primarily being used to treat recurrent malignant gliomas. The latest results with its use as a frontline treatment for malignant glioma show no real benefit over the current conventional regimen using radiation therapy and chemotherapy with temodar (temozolomide). ...Read more

12

12
My sister was diagnosed with atypical meningiomanow taking avastin (bevacizumab) what is her survival rate?

My sister was diagnosed with atypical meningiomanow taking avastin (bevacizumab) what is her survival rate?

Good: Meningiomas are usually benign tumors with excellent prognosis. Symptoms depends on the location of tumor. Atypical meningioma is more concerning and it is in a spectrum (worse than benign but better than malignant meningioma). The idea is to see the rate of growth, slow it if possible. If progressing, surgery, radiosurgery, or traditional radiation or combination of above are possible options. ...Read more

See 3 more doctor answers
16

16
How long is a woman usually on cytozen and avastin (bevacizumab)?

How long is a woman usually on cytozen and avastin (bevacizumab)?

Medication use: Avastin (bevacizumab) is a biologic used to interfere with new blood vessel growth in various tumors. It is not time-limited or sex-limited to females. The other drug is an Ayurvedic medicine and I can't comment on its use. ...Read more

17

17
Does avastin (bevacizumab) reduce male fertility?

Does avastin (bevacizumab) reduce male fertility?

No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf. ...Read more

See 2 more doctor answers
18

18
How does avastin (bevacizumab) affect male fertility?

How does avastin (bevacizumab) affect male fertility?

It doesn't (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but I don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www. Gene. Com/gene/products/information/pdf/avastin-prescribing. Pdf. ...Read more

See 1 more doctor answer
19

19
Do you know are avastin (bevacizumab) and Xeloda the same?

Do you know are avastin (bevacizumab) and Xeloda the same?

Different: Xeloda is oral chemotherapy while Avastin (bevacizumab) is a monoclonal antibody targeting vascular growth factor. Bevacizumab (avastin) is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor. It also helps with chemo by allowing entry into tumor microvascular structures while Xeloda helps to inhibit DNA synthesis ...Read more

20

20
Which is more effective: Avastin (bevacizumab) or Erbitux?

Which is more effective: Avastin (bevacizumab) or Erbitux?

Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more