Doctor insights on:
Abraxane And Avastin
Yes it is an option: The standard therapy for ovarian cancer initially is still a taxane (usually Taxol) and Carboplatin. However, Abraxane is an effective taxane down the line for recurrences, and is potentially less toxic. Avastin (bevacizumab) has been combined safely with Abraxane and the two may be helpful for recurrence management. But the question is a bit difficult to answer concretely because circumstances differ. ...Read more
Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?
Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read moreSee 1 more doctor answer
Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more
Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug,protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more
Gem for taxotere (docetaxel): Short answer is no. It cannot be substituted. Now depending upon the underlying cancer whether lung, breast, pancreatic or any other primary solid tumor, one can use taxol, Abraxane or Navelbine (vinorelbine) (they are taxanes like taxotere). If we want to move to a different agent altogether, then Gemzar or a no of other drugs would be available depending upon what the primary tumor is. ...Read more
Colon mets: Not having your chart and you in front of me makes it very hard to give you an accurate idea on prognosis. When chemo is started, that means your CA cells have gone beyond the boundaries which would have made txing it simple. The simpler the tx, the better the prgns. The harder the tx, the worse the prgns. On a positive note, f/u with your docs, stay faithful, and you might get a pleasant surprise ...Read more
Not a standard treat: Cytoxan (cyclophosphamide) and 5-fu jused to be used as first line chemo for breast cancer, but there are much more effacious drugs available now. I would not use these drugs now as first line treatment fofr anything except in special circumstances. ...Read moreSee 1 more doctor answer
Different drugs. : Chemotherapy for a hematologic cancer such as AML differs in the drugs & regimens from an epithelial cancer like prostatic carcinoma. AML typically uses Cytarabine and an anthracycline on a specific schedule. In prostate cancer, docetaxel and cabazitaxel are frequently used drugs. Of note, chemotherapy is not as common a treatment for prostate cancer, where hormonal therapy is often used. ...Read moreSee 1 more doctor answer
Biologic Therapy: Herceptin/trastuzumab is an antibody to a cell surface proteint coded for by the her2neu gene. Its present in some normal cells but in a subset of breast cancers (10-15%) there are multiple copies of the gene producing large amounts of the protein. The herceptin/trastuzumab antibody binds to that protein and reduces that aggressive nature of her2+cancer. It is usually given with chemo. ...Read moreSee 2 more doctor answers
Why has the drug temozolomide replaced the combination of procarbazine, carmustine and vincristine?
Newer treatment: In treatment of Cancer, newer drugs come along and are then compared to the standard(old/conventional treatments). If the new treatment if better(more effective or less toxic) then the new drug takes over and the older drugs put on the back burner. That is what has happened in this instance. This is what has happened in the treatment of brain tumors. ...Read more
49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?
Is avastin (bevacizumab) a good treatment for metastic colon cancer ? Are the side effects harsh ?
GOOD MEDICINE: avastin (bevacizumab) indicated for first line and second line treatment for metastatic colorectal carcinoma in combination with 5-Fluorouracil based chemotherapy side effect is long like weakness,hypertension,vomiting you can google the medicine and you can get the long list follow with your oncologist good luck ...Read more
Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?
Restate question: Hi jsalyers9. Can you restate your question with a little more information. What is being treated? What treatments have already occurred? Thanks. ...Read more