Top
30
Doctor insights on: Abnormal Marrow Signal

Share
1

1
What are some reasons my lubar MRI impression reads abnormal marrow signal suggestive for diffuse marrow replacement process.?

What are some reasons my lubar MRI impression reads abnormal marrow signal suggestive for diffuse marrow replacement process.?

Need to discuss with Dr.: Diffuse marrow replacement processes can be seen on mri. The biggest concerns are anemia, metastatic disease and lymphoma/leukemia among others. Your doctor will need to correlate this finding with other laboratory and clinical findings in order to arrive at a proper diagnosis. ...Read more

2

2
I got an MRI done on the right shoulder, There is abnormal bone marrow signal involving the scapula just deep to the acetabulum. This is t2 hyperinte?

I got an MRI done on the right shoulder, There is abnormal bone marrow signal involving the scapula just deep to the acetabulum. This is t2 hyperinte?

Probably nothing: Abnromal marrow signal without any accompanying lesions is probably insignifcnat. The doctor who ordered the MRI should review its results with you. ...Read more

3

3
A recent MRI showed an abnormal mass like marrow signal measuring 2.2 x 1.4 cm area of T1?

A recent MRI showed an abnormal mass like marrow signal measuring 2.2 x 1.4 cm area of T1?

Mass vs benign: What body part was imaged? Was it the spine or a long bone, such as the femur or humerus?
Could be a mass or benign entity, such as spinal hemangioma vs long bone enchondroma or bone infarct.
Did you have contrast administered? Did the radiology report recommend any further tests? ...Read more

4

4
What does Heterogeneous marrow signal noted with probable atypical hemangiomas at the T6 and T8 levels mean on an MRI?

What does Heterogeneous marrow signal noted with probable atypical hemangiomas at the T6 and T8 levels mean on an MRI?

Nothing w/o symptoms: What was the reason the MRI was obtained in the 1st place? Without knowing the symptoms, the MRI results are meaningless. This "heterogeneous marrow signal" could be an incidental finding. Basically, it is reporting some "fuzziness" or mixing of shades of gray in the T6 & T8 vertebra. It could be a technical error in the way the MRI was obtained. It could be a harmless web of blood vessels. TTYD. ...Read more

5

5
What does diffusely low T1 marrow signal mean?

What does diffusely low T1 marrow signal mean?

Depends: This finding can be a sign of anemia or a much more significant problem with the bone marrow. Feel free to set up a virtual consult and I'd be happy to review your specific MRI imaging and discuss the differential and recommended next steps. ...Read more

7

7
What does Minimal discogenic marrow signal abnormalities superior endplate C6 and C7 mean on a MRI of neck report?

What does Minimal discogenic marrow signal abnormalities superior endplate C6 and C7 mean on a MRI of neck report?

End plate changes: It is a manifestation of degenerative disc disease/arthritis that involves the part of the vertebral body bone that sits against the disc (called the end plate). A relatively common finding in the spectrum of degenerative disc disease. ...Read more

8

8
What is mild generalized diminished t1 marrow signal, in the cervical spine, which may reflect red marrow reconversion.?

What is mild generalized diminished t1 marrow signal, in the cervical spine, which may reflect red marrow reconversion.?

Increased blood cell: As we age, our marrow should decreased production of blood cells and become fatty. This process can reverse (reconversion) for many reasons. The most common is a mild anemia; the most common reason for this is tobacco use. You will likely need some more testing to make sure nothing is wrong. ...Read more

9

9
I've back pain. My ESR report result is 33 and MRI says altrd marrow signal intensity in ri8 side of t8 vertebral body postero-inferiorily.

I've back pain. My ESR report result is 33 and MRI says altrd marrow signal intensity in ri8 side of t8 vertebral body postero-inferiorily.

The ESR: Is mildly elevated. The MRI is nonspecific. Altered bone marrow can mean anything from edema as a result of trauma, infection, or tumor. The radiologist should provide more information about this finding, i.e. Its potential cause. That is the radiologist's job. ...Read more

10

10
Brain MRI showed low marrow signal is this concerning? I was having a followup MRI for an incidental meningioma found Dec 2016. It was stable.

Brain MRI showed low marrow signal is this concerning? I was having a followup MRI for an incidental meningioma found Dec 2016. It was stable.

It is insignificant: Marrow signal reported in a MRI is rarely helpful. Its significance, if any, is minimal. I would not be concerned about it. Just focus on the Meningioma. ...Read more

11

11
What does nonspecific heterogeneous marrow signal suggestive of red marrow reconversion on brain MRI means?

What does nonspecific heterogeneous marrow signal suggestive of red marrow reconversion on brain MRI means?

Red marrow: Reconversion usually indicates a chronic hypoxic or anemic state. For example, it is sometimes seen in heavy smokers. Talk to your doctor about what it means in your case. ...Read more

12

12
What is Heterogeneous marrow signal within the axial skeleton mean on an MRI of the right hip mean. I am a women age 60?

It doesn't mean muc: Unless you have bone pain in that area, this report carries little significance. I can not say it help us to point in any direction. So you can ignore this report unless you had increasing pain that area. Tell us why was the MRI done??? ...Read more

13

13
What is mild diminished t1 marrow signal, in which may reflect red marrow reconversion. This was result from an MRI. CBC normal. History mild anemia?

Red marrow: Reconversion occurs when areas of normal adult yellow marrow (non blood cell producing) change to red marrow (blood cell producing). This can occur in response to various conditions that increase the demand for oxygen-carrying red blood cells: chronic hypoxic states (smoking/COPD), high altitudes, high level athletes, and various anemias. Talk to your doc about what the results mean in your case. ...Read more

14

14
What does "the marrow signal in the cervical spine is decreased" mean? It says it can be correlated with a CBC. From MRI scan from 2007. Concerns?

What does "the marrow signal in the cervical spine is decreased" mean? It says it can be correlated with a CBC. From MRI scan from 2007. Concerns?

Not much: Each of the tissues in an MRI gives if a characteristic signal, which then makes it a certain appearance on the image. So the marrow signal was lower than average. This could be a normal variant, but is sometimes seen in patients with abnormalities of the marrow system which produces our blood cells; thus the recommendation to correlate with a CBC. I would just mention to your MD. ...Read more

16

16
What does "increased marrow signal in proximal radial diaphysis and distal humerus is most likely due to artifact" mean in reference to an elbow joint?

What does "increased marrow signal in proximal radial diaphysis and distal humerus is most likely due to artifact" mean in reference to an elbow joint?

Nothing: This sounds like an MRI report. Firstly, most MRIs of the elbow are done without a good reason and are not helpful. For example in you case it has raised concerns about something that is nothing.

An artifact is a false image that does not add diagnostic info or is misleading. ...Read more

17

17
What does altered marrow signal in distal femur and proximal tibia accompanied with hemosiderin deposition & thickened synovium in MRI left knee mean?

What does altered marrow signal in distal femur and proximal tibia accompanied with hemosiderin deposition & thickened synovium in MRI left knee mean?

Hemosiderin MRI: This may be consistent with a condition of the knee called pigmented villodular synovitis. This is caused by inflammation of the lining of the knee joint (synovium) and resulting deposit of breakdown of blood products. The cause is largely unknown. The diagnosis of pigmented villonodular synovitis is confirmed by biopsy, and the treatment of choice is synovectomy. ...Read more

18

18
Lumbar spine MRI shows:" The bone marrow signal is grossly homogeneous. There is no bone marrow edema, there is a left disc herniation." your suggestion?

Lumbar spine MRI shows:" The bone marrow signal is grossly homogeneous. There is no bone marrow edema, there is a left disc herniation." your suggestion?

The bone: Marrow sounds normal. It is difficult to assess the significance of the disc herniations without additional details. Best bet is to talk to your doc about the results. ...Read more

19

19
No abnormal infiltrates in the bone marrow but states 15 percent plasma cells means?

No abnormal infiltrates in the bone marrow but states 15 percent plasma cells means?

Abnormal result: 15% plasma cells is abnormally high. This may be due to
several different causes. Sometimes it may be due to an
acute infection, or another illness in the body. A more serious cause is Multiple Myeloma.

There is also Asymptomatic Multiple Myeloma in which the patient has: normal x-rays, red blood count, blood calcium and kidney function. Only some of these will develop Multiple Myeloma. ...Read more

20

20
my BMB report done for thrombocytosis and it stated "Marrow with patchy hypocellularity " also megas with abnormal spidery and/or bizarre nucleus?

my BMB report done for thrombocytosis and it stated "Marrow with patchy hypocellularity " also megas with abnormal spidery and/or bizarre nucleus?

Means little: Patchy hypocellularity is to be expected at your age; "spidery" nuclei doesn't mean anything in standard pathology, and the "bizarre" nuclei might be better charaterized. Have another pathologist read it out. There are DNA studies to check for essential thrombocythemia which is our major concern now that we ruled out a bunch of bad things which would have shown on marrow. ...Read more

21

21
What does abnormal bone marrow with neoplastic entities mean?

What does abnormal bone marrow with neoplastic entities mean?

Non-specific: "Bone marrow with neoplastic entities" is not a standard term used in pathology for diagnosing bone marrow. You should consult the doctor who provided that opinion. ...Read more

22

22
Had a bone marrow asp and biopsy. Said abnormal female karyotype and these numbers in order. Add (14) (q22) (20). It was never explained. Could you help?

Had a bone marrow asp and biopsy. Said abnormal female karyotype and these numbers in order. Add (14) (q22) (20). It was never explained. Could you help?

Need mor einformatio: You need to tell us about what made you go to see your doctor in the first instance and why was a bone marrow done? Unless you have some blood disorder, we can not interpret your chromosomal change (karyotype). You will be better off asking your doctor what it means now that he has given you this worry some report. ...Read more

23

23
What makes an a bone marrow biopsy abnormal?

What makes an a bone marrow biopsy abnormal?

Change in components: A bone marrow biopsy in a normal person will find the pattern of cells most often seen in a healthy person of that age. This would include red cells and their precursers (builders), white cells & precursers, platelet precursers & others. In illness, the pattern changes, and some or all may be abnormal. Tumor cells may take over every space& or few if any normal cells may be seen. ...Read more

24

24
Focus of hyperintense t2 and t1 signal with suppress on the stir sequence in t2 veterbral suggestive of island of fatty marrow? Same as myleomalacia?

Focus of hyperintense t2 and t1 signal with suppress on the stir sequence in t2 veterbral suggestive of island of fatty marrow? Same as myleomalacia?

No: Myelomalacia is a term that is used to refer to the spinal cord itself. It refers to some degeneration of the spinal cord. What you are describing is in the bone of the vertebral body. This is a different condition. It may represent fatty marrow-usually a benign variant. ...Read more

25

25
How bad is multiple myeloma with 40% abnormal plasma cells in bone marrow?

How bad is multiple myeloma with 40% abnormal plasma cells in bone marrow?

Depends: The number of plasma cells is not the only determinant of prognosis. Are there bone lesions on x-ray? Is kidney function normal? Has there been a response to therapy? Many patients with 40% plasma cells at diagnosis can do well for years. ...Read more

26

26
Can you have cancer (not of the blood or bone marrow) that would not show up in bloodwork? Dies leukemia always show up in abnormal bloodwork?

Can you have cancer (not of the blood or bone marrow) that would not show up in bloodwork? Dies leukemia always show up in abnormal bloodwork?

Yes: The presence of cancer frequently is not reflected by any abnormal blood tests. Leukemia usually, but not always will be reflected in an abnormal CBC (complete blood count) and differential ...Read more

27

27
MRI -Marrow edema, chondral thinning, elongated osteochondral lesion (6x17mm) lateral talar dome. Increased signal distal syndesmosis -- need surgery?

MRI -Marrow edema, chondral thinning, elongated osteochondral lesion (6x17mm) lateral talar dome. Increased signal distal syndesmosis -- need surgery?

Talar Dome Lesion: Kolleen, you have a large lesion off soft bone inside your ankle. Surgery can be an option, but attempting to create a pain free environment (from boot to just activity restrictions), contrast bathing nightly to increase circulation, Exogen bone stimulator for 9 months, repeat MRI in 6 months to see if improvement is being made, and other treatments available may avoid surgery. Dr Blake ...Read more

28

28
Mri reads as STIR signal change seen involving the Medial Femoral Condyle in keeping with Marrow Oedema (contusion injury). 4months and severe pain.?

Mri reads as STIR signal change seen involving the Medial Femoral Condyle in keeping with Marrow Oedema (contusion injury). 4months and severe pain.?

This implies a bone-: -bruise. It can linger long after an injury, just like a deep muscle bruise. The color takes a while to clear. If you had any knee injury twist or bump, of from a jump. This can be the cause. Really best to take this up with the physician that ordered the imaging. ...Read more

29

29
Son 15 month old droping platelet and homoglobin. Bone marrow show some abnormal cells but doctors said its not lukemea. What abromal are these?

Son 15 month old droping platelet and homoglobin. Bone marrow show some abnormal cells but doctors said its not lukemea. What abromal are these?

Evans syndrome?: The first question you want to ask your physicians is whether this is evans syndrome, which can be difficult to manage. The abnormality may be considerably increased platelet and red cell precursors; if the cells themselves are bizarre this may be a pediatric myelodysplastic syndrome. In any case, you have an absolute right to know the physicians' thinking. Glad junior has a proactive dad, good lu. ...Read more

30

30
Help understanding my MRI report. They mention the bone marrow singal is diffusely abnormal and hypointense on t1 and t2 weighed image. Meaning?

Meaning: There really isn't enough space here for that kind of explanation. That is best left to your ordering physician or a radiologist. ...Read more