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Doctor insights on: Abl T315i Mutation Cell Based

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Can one's DNA change during life? Does that mean that different cells in my body might currently have mutations from one another?

Can one's DNA change during life? Does that mean that different cells in my body might currently have mutations from one another?

DNA does not change: No. Cells can change; they can get damaged; they can be affected by their environment. But, the underlying DNA does not change or mutate. ...Read more

Mutation (Definition)

In genetics, a mutation is a change in the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. Mutations result from unrepaired damage to dna or to RNA genomes (typically caused by radiation or chemical mutagens), from errors in the process of replication, or from the insertion or deletion of segments of dna ...Read more


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How do cell mutations happen in fetuses?

How do cell mutations happen in fetuses?

At conception.: At conception the maternal egg or the paternal sperm cell may carry mutations that are passed on to the fetus. ...Read more

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What is the mechanism by which mutations to the cell clock cause cancer?

What is the mechanism by which mutations to the cell clock cause cancer?

Unregulated growth: The "cell clock" is often referred to as the cell cycle. Think of this as a series of stop and go lights during the lifetime of a cell. Mutations can change a "stop light" to a "green light" resulting in unregulated growth of cells. That unregulated growth can result in the cancer. ...Read more

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Thyroseq neg for mutations But interpret with caution due to marginally low expression of thyroid cell specific markers.Odds higher for benign nodule?

Thyroseq neg for mutations But interpret with caution due to marginally low expression of thyroid cell specific markers.Odds higher for benign nodule?

Probably normal: This is best discussed with your endocrinologist who can put it in perspective. If necessary you ultrasound and even biopsy can guide your therapy. ...Read more

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Thyroseq v2 was mutations NOT detected but analysis limited due to low amount of thyroid epithelial cells.So this test was useless?

Totally: B"sd absolutely right - genetic studies should only be done on an appropriate tissue specimen. To my knowlege, specimens are screened for adequacy before such testing. If the biopsy was indicated in the first place then it must be repeated - usually after an appropriate interval to allow the "needled" tissue to heal. ...Read more

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Is it safe to use kojic acid soap? I've heard that it can cause cell mutation on some mammals. I would plan to use it once a day each night.

Is it safe to use kojic acid soap? I've heard that it can cause cell mutation on some mammals. I would plan to use it once a day each night.

Check out this link.: Too much use of this soap may increase the risk of skin cancer. Discuss with ur dr or dermatologist for any concern. Take care! http://kojicacidsoap.Info/2013/05/17/how-often-should-you-use-kojic-acid-soap/. ...Read more

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Do all sickle cell patients have the exact same mutation?

Sickle cell anemia: There are many different types of sickle cell anemia. How bad someone's disease is depends on which part of africa their family originally came from and whether the sickle cell gene is combined with any other hemoglobin mutations. For instance, sickle cell + hemoglobin c or sickle cell + thalassemia often gives the patient milder disease than plain sickle cell anemia. ...Read more

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Is there a correlation between sickle cell and the jak2 mutation?

It doesn't appear so: I can find no reports of an association between sickle cell anemia and jak2 mutations. Jak2 is a gene involved in promoting growth of red blood cells. The confusion may have arisen from some reports suggesting that stimulators of jak2 might be useful in gene therapy treatments for sickle cell disease. ...Read more

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Kras ?Adenocarcinoma? Mutation? New trial drugs with Ins. & Tissue Eval.  What is the doctor really saying to 70 year  NSCLC pat.9 month ..meets w/new cell grow

Kras ?Adenocarcinoma? Mutation? New trial drugs with Ins. & Tissue Eval.  What is the doctor really saying to 70 year  NSCLC pat.9 month ..meets w/new cell grow

Describing the Tumor: So it sounds like the oncologist has really just given you a lot of descriptors to help describe the tumor. The idea is that if we know this information we can select therapies that are more likely to work. For example, whether a patient has a k-ras mutation helps predict whether a tumor may be resistant to a certain drug. ...Read more

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How does a genetic mutation cause sickle-cell disease?

How does a genetic mutation cause sickle-cell disease?

Important gene...: Sickle cell anemia is caused by a mutation in the gene that tells your body to make hemoglobin. Hemoglobin allows red blood cells to carry oxygen from your lungs to all parts of your body. In sickle cell anemia, the abnormal hemoglobin causes red blood cells to become rigid, sticky and misshapen. These abnormal red blood cells lead to the various symptoms of the disease. ...Read more

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