Doctor insights on:
Abdominal Carcinamatosis From Breast Cancer Metastasis
Breast Cancer (Female) (Definition)
Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast on an annual basis. ...Read more
All forms: of breast cancer can be considered serious, but to answer your question, yes, breast cancer with lymph node involvement is potentially curable, but the probability depends on a number of factors. Survival rates are very high if the tumor is small and the lymph node involvement is minimal(stage 1B), and become worse with increasing tumor size, extent of node involvement, and distant metastases. ...Read moreSee 1 more doctor answer
How can angiogenesis and invasion influence tumor growth and metastasis in a patient with breast cancer?
The general concept: The general concept behind angiogenesis promoting cancer metastasis growth is that cancer cells / tumors use more nutrients and therefore need more blood flow than usual to grow to a large size, and that if we can inhibit this new vessel growth stimulated by tumors, we can limit the growth of the tumor. ...Read more
History of invasive breast cancer since 2006. Oncologist ran a CTC test, came back positive with level of 1 CTC. Does this mean I have metastasis now?
Ask your ordering dr: Glad you have well survived from invasive breast cancer. Your current CTC 0f 1 suggests your further survival is very favorable; that's good clinically. For more, review article in https://www.cellsearchctc.com/clinical-applications/interpretation-of-results. Of course, it would be most logical to ask the ordering oncologist since s/he knows more about your individual conditions than anyone online ...Read more
Staging: Breast cancer staging is described as t (tumor size), n (lymph node metastases) and m (metastases to sites like bone, lung, etc). In a simplified short answer: stage 0 is non-invasive breast cancer, stage 1 is no spread to lymph nodes, stage 2 and stage 3 has lymph node spread and larger tumors, and stage 4 would have metastases to other organs. ...Read more
I had very low numbers in a grade 3, stage 3 er+ breast cancer (no lymph involvement), what are the chances of metastasis elsewhere?
Not sure what..: ...You mean by "low numbers". If you truly had a stage 3, node negative cancer, it would be a t4n0m0 (stage iiib). Being er+ is good but a grade 3, stage 3 still has a fair risk of relapse. You need an aggressive approach with chemo, surgery, radiation, and endocrine therapy. My advise: do your best to complete therapy and do not focus too much in numbers or odds. Best 2u. ...Read moreSee 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more
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