Doctor insights on:
Abcde S Of Melanoma
I have a mole with 2 out of 5 of the abcde symptoms (melanoma) its border and color. Lesion benign?
Metastasis: Stage IV (4) melanoma is the highest stage that a melanoma can reach. It is diagnosed by finding distant spread or metastasis to other parts of the body. Stage is different from clark's levels and breslow levels, although these can impact lower stages. (ajcc cancer staging manual, 7th ed., 2010). ...Read moreSee 3 more doctor answers
Nodular melanoma: Three of the four types of melanoma remain superficial in the epidermis and grow RADIALLY (laterally), often for several years, before entering the VERTICAL GROWTH PHASE where they grow downward and invade the dermis with the potential to metastasize. The fourth type of melanoma is nodular melanoma which STARTS in the vertical growth phase and can metastasize from the outset. ...Read moreSee 1 more doctor answer
Aggressive cancer: Melanoma develops from melanocytes cells of the lower layers in the skin. These cells produce pigments and the color of skin. When they form into cancer it can grow radially and deeply which can be dangerous as it can subsequently spread to other areas of the body. There are genetic predispositions as well as ultraviolet radiation exposure and sunburns are risk factors. ...Read moreSee 4 more doctor answers
Depends on location: Surgical removal of skin cancers is effective and the risks are associated with the size and location. Bleeding, infection and poor cosmetic outcome are all risks. Delayed healing in areas of poor blood flow is also a risk. Other treatments such as radiation can be successful as well with similar results and better cosmetic outcomes. ...Read moreSee 2 more doctor answers
Skin cancer: In its most typical form, melanoma is a cancer that originates in cells of the skin called melanocytes. In some cases melanoma can spread to other organs from the skin. More rare types of melanoma start in the eyes, colon, mouth, bladder and other organs. ...Read moreSee 2 more doctor answers
Yes: All melanomas are considered malignant however they have different levels of metastatic potential. This means that some melanomas have the ability to spread to other parts of the body while others, especially in situ melanomas, have little or no risk of metastasis. ...Read moreSee 1 more doctor answer
You have asked...: ...One of the most controversial questions in dermatology. One faction believes that dysplastic nevi are precursors of melanomas, and should be excised before they become melanomas. Another faction believes dysplastic nevi are benign moles that never become melanomas. There is evidence to support both arguments. ...Read moreSee 1 more doctor answer
What's the likelihood of a completely normal looking mole (with no worrying features) being melanoma?
Near zero: It will show signs of malignancy before it is able to kill you ...Read more
Yes: Melanoma is a lethal disease if untreated, early detection and excision will cure melanoma.Awareness and education is essential to cure, which is done by melanoma walks in your local area, several organisations like melanoma research alliance, melanoma.Org etc contact your local american society office for more information or your local hospital. ...Read moreSee 1 more doctor answer
My pathology report states junctional and lentiginous melanocytic nevus, extending to the peripheral edge. Is this melanoma?.
Mole, not cancer: Here is a translation of your path report: Junctional- location as it relates to depth in the skin, the junction between epidermis and dermis. lentiginous- means flat dark spot, melanocytic- made up of pigment cells (melanocytes), nevus - a lesion that contains nevus cells a type of melanocyte, aka "mole". This is a benign spot that appears to have been completely removed. Not a malignancy. ...Read more
Spread of cancer: Melanoma in situ is the term used to describe when the skin cancer only involves the surface (epidermis) of the skin and has not spread to any other tissues in the body; there is a 99.9% five year survival rate. Invasive melanoma indicates that the cancer has spread below the surface into the dermis of the skin. Metastatic melanoma indicates spread of the cancer to other areas in the body. ...Read moreSee 3 more doctor answers
What is the likelihood of a dysplastic nevus turning into melanoma? I can't find any relative data online
Depends: It depends on several factors, like the total # of dysplastic nevi, nevi size, patient age, family history, etc. The reported annual transformation rate of any single mole into melanoma is ?1 in 200,000 in people 60. Check out this paper by Tsao H, et al, in Archives of Dermatology in 2003: The Transformation Rate of Moles (Melanocytic Nevi) Into Cutaneous Melanoma. ...Read more
What are the chances of a completely normal looking mole (with no concerning characteristics) being melanoma?
Can't say.: AAD Malignant Melanoma screening: ASYMMETRY: 1 half is unlike the other. BORDER: irregular, scalloped or poorly defined. COLOR: varied with shades of tan, brown or black; or white, red or blue. DIAMETER: > 6 mm. EVOLVING: mole /skin lesion looks different from the rest or is changing in size, shape or color. An irregular mole that itches, bleeds or is painful is worrisome for possible cancer. ...Read more
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