Doctor insights on:
Depends: It depends on what the lab standards are for the ige test. Usually, a simple cut off is between 60-100. And elevated ige might mean nothing without symptoms. Same with a low level of ige. ...Read more
Maybe: Nothing it depends on symptoms. Talk to the provider who ordered the test ...Read more
Decoupling: Allergic illness occur when allergens activate mast cells releasing biochemicals. Allergens interact with mast cells through ige antibodies attached to mast cell receptors. Each ige antibody is specific for an allergen. Ige lasts for months but ultimately degrades & must be replaced. Anti-ige blocks the replacement process. Mast cells become denuded of ige & can no longer respond to allergens. ...Read moreSee 1 more doctor answer
I m 25y student. Can you tell me steroids are safe for life time.... I take deflazcort 30mg daily in the morning due tuo high IgE level.. ?
Are pseudoallergies to meds less dangerous than "true" IgE mediated allergies? Are they less likely to grow in severity over time?
Both can be severe: For a medication allergy, a true ige mediated one can be as severe as one not mediated by ige. Anaphylaxis vs. Anaphylactoid. Same severe symptoms, just not ige mediated. These non-ige reactions can be to: blood products, ace inhibitors for high blood pressure, aspirin, nsaids, narcotics, anti-convulsants, and others. The severity is difficult to predict---treatment is same: avoidance! ...Read more
Is there a specific test that can be run to tell if my high IgE (>770) is a result of mercury toxicity?
I have urticarial vasculitis, high ige, high red blood cell count, possible tmj, joint pain, what could this be? Oh and hernia.Esr is 20.
TMJ maybe the clue: Look at your tongue in the mirror and see if there are little square indentation around the edge. If so, that is because you push the tongue (unconsciously) against the back of the teeth and clench your jaw. That indicates a stressed person from 1. Poor diet, 2. Work or family stress 3. Any cause of fear. Check out your diet and try meditation that is easy to learn. ...Read moreSee 2 more doctor answers
See an allergist: The significance of ige test results is completely dependent on your history, and the relevance of the tests. I would recommend scheduling an appointment with a board-certified allergist to help interpret the test results. ...Read more
Most Likely Allergy: IgE levels above the normal range are common amongst patients with allergies, asthma, and eczema. If you have these symptoms or diseases then this is nothing to worry about. If you don't have any of these problems, it could represent a parasitic infection and that is usually associated with an elevated eosinophil count on a routine blood count. ...Read more
Are you saying an IgE of zero means imunodeficiency? Are there any additional testing recommendations.
Genetics: The tendency to make more ige in response to foreign substances that enter the body (aka allergens) is inherited. Allergies and parastic infections are the common reasons why people develop high ige levels. There are some rare disorders associated with increased risk of infections associated with very high levels of ige. A board-certified allergist can help sort this out for you. ...Read moreSee 1 more doctor answer
My one year old is being treated for low IgG and low IgA levels then after being re tested her IgG and IgA were ok but now her lgm and IgE are low wha?
Hypoimmuneglobulinem: First question to you is: why your one year old was diagnosed with low immunoglobulins? Next question is: how is he being treated? Is he receiving IV igg? Now lastly, is he under care of a pediatric immunologist in an academic institute? ...Read more
Yes: Treatment of atopic disease, such as atopic dermatitis or asthma, can result in lowered IgE. The B-cells that make IgE depend on certain signals in the body to live and produce antibody. Time, changes in environmental/food/drug exposure, medicating specific diseases can all result in decreases in both total and specific IgE levels ...Read moreSee 1 more doctor answer
Can Be...: Elevated total serum IgE is seen in mainly allergic diseases like allergic rhinitis and eczema. It is also seen in some primary immunodeficiencies, parasitic and viral infections, certain inflammatory diseases, and some malignancies. Atopic conditions like allergic rhinitis and eczema definitely have a genetic component to them. ...Read moreSee 1 more doctor answer
No: Of the 5 types of antibodies, ige is the one involved in allergy triggering allergic rhinitis, asthma & food allergies. Cat allergy occurs when your immune system makes ige against cat proteins in cat hair or dander. Peanut allergy occurs when you make ige against peanut proteins. Cashew allergy requires ige to cashew. Each specific ige antibody defines an allergy to the substance it recognizes. ...Read moreSee 1 more doctor answer
Trick question: Are you studying immunology? The extra domain on ige indicates a unique role for the c2 domain in the interaction between ige and fcri. C2 reduces the off-rate of the ige/fcri, thereby resulting in a more stable complex. It is felt that the domain on igm co-contributes to the pentamic structure production. ...Read more