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Doctor insights on: A False Positive Anti Dsdna

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At mayo clinic i tested positive for anti dsdna. Latest test says negative (l) dsdna. If positive are you always positive?

At mayo clinic i tested positive for anti dsdna. Latest test says negative (l) dsdna. If positive are you always positive?

Depends on lab: A lot of this depends on what your problems are. Specifically however laboratory studies can sometimes cause conflict. It depends on whether the test was done the correct way, and lab tests can vary even day today. Some labs do a better job than others. This may also depend on the technique of the type of dna test that was done. Your physician can help clarify this. ...Read more

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Normal lab test for anti dsdna is < 1:20 . Is 1:20 considered negative or positive or borderline ? Thank you

Basically negative: With that number it is basically negative, but doctors do not treat numbers we treat patients so that in itself does not rule out lupus. ...Read more

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I tested positive ANA and anti dsdna, later testing neg. I have past diagnosis that may apply to lupus but do not do well articuliatng at dr. Help?

Tests and lupus: The question is why is the doctor running the tests? If your symptoms and physical signs are a strong indication of possible lupus, positive dsdna helps confirm a diagnosis of lupus. If the tests are run for "screening", they are worthless tests. No diagnosis of lupus or connective tissue disease can be made on antibody studies alone. ...Read more

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I've had a positive ANA and anti-dsdna. Plaquenil helped but i had mood changes and went off of it and pain is back - what else can I try?

I've had a positive ANA and anti-dsdna. Plaquenil helped but i had mood changes and went off of it and pain is back - what else can I try?

See below: In recent yrs, there have been more choices in meds for ra. Talk to your rheumatologist for your other options, for oral meds, ypu have methotrexate, sulfasalazine, xeljanz. The injectable meds are humira, remicade. Don't jusy stop medications without telling your dr. Be well. ...Read more

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My doctor won't refer me to a rheumatologist, I tested positive for ANA and anti dsdna. He Says I don't need to see one, should I insist to see one?

My doctor won't refer me to a rheumatologist, I tested positive for ANA and anti dsdna.  He Says I don't need to see one, should I insist to see one?

Possibly: A simple ANA test is positive in 20-30% of healthy people who won't ever develop autoimmune disease. However, a positive anti-dsdna test is much more specific for lupus.It doesn't make the diagnosis,but if you have any concerning symptoms like rash, arthritis, unexplained fevers, chest pain, shortness of breath or other abnormal labs (high ESR, low WBC or platelets, protein in urine), then insist! ...Read more

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My left hand and arm have been going numb, with shoulder and neck stiffness in morning. Previously tested positive for Anti dsDNA. Gp thinks nothing?

My left hand and arm have been going numb, with shoulder and neck stiffness in morning. Previously tested positive for Anti dsDNA. Gp thinks nothing?

Need more evaluation: Numbness may be nerve-related and you may need neurology evaluation. It may be metabolic, like thyroid or sugar. It may be mental, like anxiety disorder. Positive anti-dsDNA antibody test may indicate an autoimmune disease such as lupus. You need to see a rheumatologist for further testing to confirm this or remove this as a possible cause. ...Read more

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I had some reumatology tests, and the anti-dsdna value is 43.2 u/ml. Should i be worried or am suspect of les? Thank you very much

I had some reumatology tests, and the anti-dsdna value is 43.2 u/ml. Should i be worried or am suspect of les? Thank you very much

Possibly: The dna positivity is suggestive of lupus if the clinical picture is consistent with lupus. The dna may occasionally be positive in other disorders. ...Read more

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What do you recommend if I have elevated ANA and anti dsdna antibody?

What do you recommend if I have elevated ANA and anti dsdna antibody?

See details: I would recommend you consult with a rheumatologist to determine if these values have any clinical significance. ...Read more