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Doctor insights on: Zoloft

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Dr. Heidi Fowler
1,048 Doctors shared insights

Zoloft (Overview)

Zoloft is a serotonin reuptake blocker which is a kind of antidepressant drug (psychiatric drug).


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What is zoloft (sertraline)? What is it used for?

What is zoloft (sertraline)? What is it used for?

Zoloft (sertraline): Sertraline (Zoloft/ Lustral) is one of the Selective serotonin reuptake inhibitor (SSRI) antidepressants. It works primarily by increasing serotonin. It is is FDA approved for the treatment of major depressive disorder, panic disorder, social anxiety disorder, post traumatic disorder, obsessive compulsive disorder, premenstrual dysphoric disorder and body dysmorphic disorder. ...Read more

Dr. Heidi Fowler
1,048 Doctors shared insights

Zoloft (Overview)

Zoloft is a serotonin reuptake blocker which is a kind of antidepressant drug (psychiatric drug).


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How exactly am I supposed to feel after being on 100 mg of Zoloft (sertraline) for two months? Also is it okay to exercise and lift vigorously on ritalin?

How exactly am I supposed to feel after being on 100 mg of Zoloft (sertraline) for two months? Also is it okay to exercise and lift vigorously on ritalin?

Symptoms control: The goal of taking medication is to control symptoms. I would go with the checklist that originally lead you to take medications and see if those symptoms have improved. Continue to find right dose or medication until you see significant improvement or noticeable change. If you are not sure if you have felt change, probably medication is not working. ...Read more

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Please describe the medication: zoloft (sertraline)?

Please describe the medication: zoloft (sertraline)?

Zoloft (sertraline): Sertraline is a selective serotonin reuptake inhibitor type of antidepressant, used to treat depression & anxiety disorders. ...Read more

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What is the highest safe dose of Zoloft which can a doctor prescribe for a fast metabolizer person taking 120 mg strattera (atomoxetine) and fish oil? 200 mg?

Strattera (atomoxetine) and Zoloft: The primary issue is that zoloft raises blood levels of strattera (atomoxetine) in rapid metabolizers, increasing the strattera (atomoxetine) 3-4 fold in the blood stream. Therefore I would say that 300-400 mg of zoloft is reasonable, but the dose of strattera (atomoxetine) should probably be 18 mg per day to 25 mg per day max. Best wishes. Also see options at:
www. Ocfoundation. Org/glutamate. Aspx
the international ocd foundation (iocdf). ...Read more

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I was prescribed Zoloft (sertraline) and don't want it. Can I pour it down toilet?

I was prescribed Zoloft (sertraline) and don't want it. Can I pour it down toilet?

Talk to your doctor: First, it is not a good idea to flush meds down the toilet due to filtration and sanitation concerns. It is best to have your physician's office, pharmacy or the police station dispose of them properly. As far as discontinuing zoloft (sertraline) on your own, I would strongly recommend that you speak with your doctor about your concerns with yhe med. ...Read more

Dr. Alan Ali Dr. Ali
1 doctor agreed:
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Can a lactating mother use Zoloft (sertraline) tablets?

Dr. Alan Ali Dr. Ali
1 doctor agreed:
Can a lactating mother use Zoloft (sertraline) tablets?

Zoloft (sertraline): Not advised, due to zoloft (sertraline) being transmitted in breast milk, hence possible side-effects to baby. ...Read more

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Has anyone ever used Zoloft (sertraline) while pregnant and had problems?

Zoloft (sertraline): We discuss risks & benefits of taking medications during pregnancy, especially during first trimester. If zoloft (sertraline) is absolutely needed during that time, the minimum effective dose is recommended, with more frequent followup visits, both with us & also with the ob/gyn are in order. So far, no complications are reported. ...Read more

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How does Zoloft (sertraline) work?

How does Zoloft (sertraline) work?

Zoloft (sertraline): Zoloft (sertraline) is one of selective serotonin reuptake inhibitors, hence produces elevation in serotonin levels which produce reduction in symptoms of depression & anxiety. ...Read more

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What works after Zoloft (sertraline) fails?

What works after Zoloft (sertraline) fails?

Varies: Antidepressant failure for depression would be no response t an adequate dose for 6 to 8 weeks. There are different classes of antidepressants, and while some may respond to an antidepressant in the same class as the one just tried, often it is helpful to try one of a different class. Cognitive behavioral therapy can also be very helpful. Please speak to the your physician regarding options. ...Read more

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How long does Zoloft (sertraline) take to kick in at 150 mgs.?

Hope you didn't: Start at 150 mg - and worked up to it. It often takes 4 to 6 weeks at an optimal dosage to really start feeling the effects. Occasionally it may start to kick in at 2 weeks. Take care. ...Read more

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My dr said I could be off of Zoloft for 24 hours and then start 10mg Lexapro (escitalopram) is that safe been on Zoloft for about 15 years on 100mg since sept.2013?

My dr said I could be off of Zoloft for 24 hours and then start 10mg Lexapro (escitalopram) is that safe been on Zoloft for about 15 years on 100mg since sept.2013?

They r SSRIs: I've switched pts directly from one sari to another--usually no problem--paxil can be a problem discontinuing bit others are usually ok. ...Read more

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Can I safely stop taking Zoloft (sertraline) cold turkey?

Can I safely stop taking Zoloft (sertraline) cold turkey?

It's safe....but: It is safe but you might experience some disconinuation sx--dizziness flu like symptoms some pts describe electric "zaps" in their heads-- probably better to wean off gradually. ...Read more

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How dangerous Zoloft (sertraline) overdose?

How dangerous Zoloft (sertraline) overdose?

Zoloft (sertraline) Overdose sx's: May include: nausea, vomiting, dizziness, drowsiness, tremor, agitation, ^ or v heart rate, seizures, fainting, hallucination, coma, delirum, ^ blood pressure & death. ...Read more

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Does Zoloft (sertraline) expire? If so how long does it take to be harmful? Or does it just degrade?

Does Zoloft (sertraline) expire? If so how long does it take to be harmful? Or does it just degrade?

Less effective: Yes it expires, which means it is past its point of maximal potency. Please check for the expiration date on the sample package or the date of your prescription. For most medications, including Zoloft, (sertraline) the expiration date is the point at which either the medication has degraded 10% from the date of manufacturing or toxic chemicals have built up (Exp. Tetracycline -> kidney damage Fanconi's synd) ...Read more

Dr. Alan Ali Dr. Ali
2 doctors agreed:
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Is tinnitus a side effect of zoloft (sertraline)?

Dr. Alan Ali Dr. Ali
2 doctors agreed:
Is tinnitus a side effect of zoloft (sertraline)?

Zoloft (sertraline): Very occasionally, dose related, or could be a symptom of anxiety. ...Read more

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What are the common side effects of zoloft (sertraline)?

What are the common side effects of zoloft (sertraline)?

Ones pts complain ab: Queasy stomach diarrhea delayed ejaculation anorgasmia restlessness. ...Read more

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How long does it take for Zoloft (sertraline) to leave your system after you stop taking it?

How long does it take for Zoloft (sertraline) to leave your system after you stop taking it?

5 days: 1/2 life is 1 day, 5 half life's to clear. Assuming you are a normal metabolier 5 days would pretty much do it. ...Read more

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How long does insomnia last with zoloft. I've been on it for 3 weeks and now taking Ambien (zolpidem) and still can't sleep. How long does insomnia last on zolof?

How long does insomnia last with zoloft. I've been on it for 3 weeks and now taking Ambien (zolpidem) and still can't sleep. How long does insomnia last on zolof?

It varies: The highest risk period for antidepressant side effects is the first 10-14 days after starting, but side effects can last up to a month before resolving. However, your insomnia sounds quite severe and given it has already been 3 weeks, in my opinion, likely warrants a change in medication. ...Read more

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How long does insomnia last when on zoloft (sertraline). Will this side effect go away in time.

How long does insomnia last when on zoloft (sertraline). Will this side effect go away in time.

See below: Insomnia is a possible side effect of zoloft (sertraline). After discussing w/ your prescribing doctor, one option would be to take it in the morning to avoid the effects. Another is to discuss about switching to another medication. Speak w/ your prescribing doctor about it. Also, you can help to sleep better, by avoiding caffeine, alcohol, ; bright lights near bedtime. Try to regularize your sleep schedule. ...Read more

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How long do the side effects of Zoloft (sertraline) last? How long till the medicine is effective and I start noticing a difference in myself?

How long do the side effects of Zoloft (sertraline) last? How long till the medicine is effective and I start noticing a difference in myself?

Sertraline effects: Some Pts notice mild improvement in mood or anxiety within days of starting an SSRI (doses are adjusted daily in hosp). pts will need to be on a therapeutic dose for up to 8 weeks to see full benefits of the med. Pts also differ with respect to SEs. Most Pts have only self limited or rather tolerable SEs (like dry mouth). Rarely, more serious SEs occur. Talk to your doc about your risks/benefits ...Read more

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Could Zoloft (sertraline) be cut in half?

Yes: Many zoloft (sertraline) tablets are scored, and are easily cut in half. ...Read more

Dr. Alan Ali Dr. Ali
1 doctor agreed:
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Black box warning Zoloft (sertraline) effects to wear off?

Dr. Alan Ali Dr. Ali
1 doctor agreed:

Zoloft (sertraline): Warning exists while taking the medication.

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Dos Abilify (aripiprazole) 2mg interact withe Zoloft 50mg?

Probably safe: Low-dose Abilify (aripiprazole) can be an effective and fairly safe augmentation strategy to add to antidepressants -- but should only be used under supervision by a psychiatrist. ...Read more

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What are the interactions between Zoloft (sertraline) and melatonin if any?

What are the interactions between Zoloft (sertraline) and melatonin if any?

Zoloft/Melatonin: No interactions. Only caution when taking melatonin is if u r on medications that suppress the immune system, blood thinners, diabetes medications, & birth control pills. ...Read more

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To add to a question I asked a few minutes ago, I'm very frustrated in finding the right combination of Zoloft (sertraline) and klonopin that will work. Thank you?

To add to a question I asked a few minutes ago, I'm very frustrated in finding the right combination of Zoloft (sertraline) and klonopin that will work. Thank you?

Frustration?: I didn't see your other question, but if you are frustrated with your medications and the way they're working or not working, you need to take it up with your own doctor. There are many possible reasons for medicines not seeming to work -- anything from other existing conditions, need to change dosage, wrong diagnosis, or need to change medication itself. Good luck in talking with your doctor! ...Read more

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Which of these meds or med combinations could cause a bad erection when waking up? Zoloft (sertraline) 100 mg, gabapentin 600 mg, intuniv, 2 mg, or clonazepam 1 mg?

Which of these meds or med combinations could cause a bad erection when waking up? Zoloft (sertraline) 100 mg, gabapentin 600 mg, intuniv, 2 mg, or clonazepam 1 mg?

Less likely drugs: Most likely none iof these meds, but you may be awakening in middle of a rem sleep cycle and have an erection. Rem cycles are when you dream, recur every 90 minutes or so and are of short duration.
I have had a similar complaint with Intuniv in one patient. ...Read more

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Can you mix Zoloft (sertraline) and weight loss pills?

Zoloft (sertraline): I would not recommend that, due to excess stimulation effect (agitation, anxiety, etc.). ...Read more

Dr. Heidi Fowler
1,094 Doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more