Doctor insights on:
What Does Duchenne Muscular Dystrophy Feel Like
Genetic muscle issue: Dmd is a genetic disorder in which there is a mutation in dystrophin, a structural protein found in muscle cell membrane. It causes progressive weakness that typically starts in the legs and pelvis, but eventually spreads throughout the body and also compromises breathing. There are symptomatic treatments, but no cure. ...Read moreSee 1 more doctor answer
Muscular dystrophy includes a number of disorders which are associated primarily with abnormalities of the architecture of the cells, often causing changes in size and function (weakness). These disorders are typically inherited, and recognized early in life, although there are of course exceptions to this. Prognosis is based on the type of MD and expression ...Read more
Boys: Young boys with first signs being lower extrity weakness. ...Read more
Please help! what is the difference between duchennes muscular dystrophy and myotonic muscular dystrophy?
Good question.: The long answer reqires that you go to the internet so you can look at the typical facial features of myotonic dystrophy. The two conditions are not similar in presentaion. You should go with the long answer. ...Read more
See link below: "duchenne results in progressive loss of strength and is caused by a mutation in the gene that encodes for dystrophin. Because dystrophin is absent, the muscle cells are easily damaged. The progressive muscle weakness leads to serious medical problems, particularly issues relating to the heart and lungs." - see more at: http://www.Parentprojectmd.Org/site/pageserver?Pagename=understand_about#sthas. ...Read more
Muscle disease: Congenital myopathy means a disease of muscle present since birth, usually inherited. The congenital myopathies are due to several genetic defects, mostly associated with muscle energy use. Usually, people have muscle weakness or damage that is mild and presents in teen or older years. Muscular dystrophy is a congenital myopathy but much more severe and not usually under this name. ...Read moreSee 1 more doctor answer
Inborn muscle diseas: Nih website has lots of excellent information: http://www.Ninds.Nih.Gov/disorders/md/md.Htm "the muscular dystrophies (md) are a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. Some forms of md are seen in infancy or childhood, while others may not appear until middle age or later. ". ...Read more
See below: Usually first become apparent with balance issues such as walking. A thorough history and physical by a medical physician before coming to a diagnosis on your own is recommended ! good luck thank you. ...Read more
Weak: Atrophy (muscle wasting) is often sneaky and painless. The wasted muscle feels weak, and often 'untrustworthy'. A knee may buckle if the quad is atrophied, or grip may fail and cause dropping of objects with hand atrophy. Sometimes patients feel an aching due to fatigue, or even trembling. In some cases, twitching or spasms can occur. ...Read moreSee 1 more doctor answer
See below: It is caused by an alteration (mutation) in a gene, called the dmd gene that can be inherited in families in an x-linked recessive fashion, but it often occurs in people from families without a known family history of the condition. Individuals who have dmd have progressive loss of muscle function and weakness, which begins in the lower limbs. ...Read more
It is recommended: to begin corticosteroids early to slow the loss of muscle strength, though they may improve muscle strength if started when the child begins to decline. Most boys with DMD are wheelchair-bound by age 10-12 years. In many cases oral steroids prolong ambulation by 1-3 years. Join Muscular Dystrophy Association India, http://www.mdindia.org for information & support. ...Read more
Start with this link: http://www.genome.gov/19518854Get a more detailed answer ›
Muscle disease: Muscular dystrophy is a worsening disorder that causes muscle weakness. The worst kind is duchenne's dystrophy, that affects only boys, leads to severe weakness, and wheelchair needs, breathing difficulties in the teens. Milder forms can present later or not cause as much disability. These are genetic (runs in families) disorders. ...Read moreSee 1 more doctor answer
Muscle weakness: Dmd is a condition when muscles start to die prematurely. It starts in early childhood, leads to weakness of voluntary muscles such as those of hips, pelvic area, thighs and shoulders. Calves are often enlarged. Eventually it involves all muscles including that of heart and that control breathing. Life span is shortened to less than 30 years. It is a genetic condition primarily in boys. ...Read moreSee 1 more doctor answer
Bad disease: This is a group of muscle diseases that all show progressive muscle decline over time. There are a variety of forms, varying from mild to severe. With progressive treatments and care, there are men surviving into their 30's forties and even 50's now. ...Read more
Not really: CPK / ck / creatine kinase is high in duchenne's because it leaks from the cells carrying the abnormal gene. Levels fluctuate in dmd patients as in everyone else with activity, and toward the end they may drop as muscle mass diminishes. Dmd is a cruel disease and if you or someone close to you is affected, you have my sympathy. Thank you for asking. ...Read more
Amount of Dystrophin: The two conditions differ in their severity, age of onset, and rate of progression. Mutations in the dmd gene cause duchenne and becker forms of muscular dystrophy (dmd and bmd, respectively). Mutations that lead to an abnormal version of dystrophin that retains some function usually cause bmd, while mutations that prevent the production of any functional dystrophin causes dmd. ...Read more
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