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Doctor insights on: Vdrl/Rpr Positive For Syphilis

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Vdrl weekly reactive, tpha negative and HIV negative then?

Vdrl weekly reactive, tpha negative and HIV negative then?

VDRL is non specific: Negative tpa (alteplase) indicate no syphilis . You may need to repeat test. It will be better practice protected sex. ...Read more

Dr. Austina Cho
74 doctors shared insights

Rpr (Definition)

Rapid plasma reagin (rpr) is a blood test that looks for non-specific antibodies that may indicate that the organism (treponema pallidum) that causes syphilis is present. The term "reagin" means that this test does not look for antibodies against the actual bacterium, but rather for antibodies against substances released by cells when they ...Read more


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Would HPV cause a false positive HIV ELISA test?

Would HPV cause a false positive HIV ELISA test?

It shouldn't: Hpv shouldn't cause a false positive elisa. But see what the follow up western blot shows. ...Read more

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Would ghonnorea or clamidia cause false positive HIV ELISA test?

Would ghonnorea or clamidia cause false positive HIV ELISA test?

Possible: The elisa test can be affected by different infections, causing a false-positive result. After any positive elisa, a follow-up test is performed by a 'western blot' which takes longer to perform, but gives a more sensitive answer. If you or someone you know had a positive HIV by elisa, they absolutely need the follow-up testing (including a full std/sti work up). ...Read more

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Positive HIV screener test at blood donation... Negative IFA and Negative NAT... False positive?

Positive HIV screener test at blood donation... Negative IFA and Negative NAT... False positive?

Yes: The initial screening test for HIV is very sensitive, but not very specific. The back up screening tests are much more specific for HIV. ...Read more

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Can RPR test for syphilis give false negative?If syphilis is highly suspected should I retest for it ?

Can RPR test for syphilis give false negative?If syphilis is highly suspected  should I retest for it ?

Prozone effect: False (-) in RPR syphilis testing occurs when there is a prozone effect. Why? It's because the concentration of syphilis antibodies is so high, it interferes with the antigen-antibody interactions that result in a (+) reaction. A false (-) result can also occur during primary syphilis since not enough time has passed to allow high enough antibody levels for a (+) reaction to occur. ...Read more

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Tested false positive ELISA HIV test last month. Negative ifa and western blot and naat. 2 negative oraquick all 1 1/2 year post exposure. Hiv?

Tested false positive ELISA HIV test last month. Negative ifa and western blot and naat. 2 negative oraquick all 1 1/2 year post exposure. Hiv?

Negative: If nat was negative at 6 months after exposure you not likely to have hiv. Given all the negative test results, you should not worry about the one apparently false positive. ...Read more

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What can cause false positive ELISA HIV tests?

What can cause false positive ELISA HIV tests?

Unknown: There is not any real or valid answer to this. It is unknown. The only known reason would be previous participation in a specific HIV vaccine trial where some form of antibody response. But in one who have not so participated the answer is unknowable. ...Read more

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Can an HIV antibody screening test be positive but the western blot negative?

Yes: There are 2 reasons for this kind of result: (1) a false positive, or (2) early infection before seroconversion. In someone at low risk for HIV without symptoms, another negative WB in 1 month means there's no infection. In someone at risk or with symptoms of acute infection, a viral load can be helpful. The new 4th generation antigen/antibody tests will eliminate this problem. ...Read more

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Tested positive for Lyme disease IgM but my western blot test came back negtive?

Tested positive for Lyme disease IgM but my western blot test came back negtive?

Then it's not Lyme: Lyme disease can be tricky -and you want to make sure you see someone like an Infectious Diseases doctor who knows how to treat it. The diagnosis is actually based on clinical findings, and the lab testing is generally 'supportive'. Since you're Western blot is negative, then it's very unlikely you have Lyme. There are other diseases that could cause 'Lyme-like' symptoms -and good to get evaluated ...Read more

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What causes false positive HCV antibody test results?

What causes false positive HCV antibody test results?

Misinformed?: Who told you that your hep c test was false? If you have no viral load that means you cleared an infection. Are you sure you are getting the right advice? ...Read more

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Ana screen, ifa positive a (negative) means?

Ana screen, ifa positive a  (negative)   means?

Nothing by itself: One person in four tests positive. The vast majority of these people have no problems. The clinical picture is key, and how high the titer is may be helpful. ...Read more

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Can negative test results be trusted for a prostitute with HIV antibody rapid test and HIV duo test?

Can negative test results be trusted for a prostitute with HIV antibody rapid test and HIV duo test?

Not necessarily: If the person just acquired the infection, she or he may be carrying the virus that will not be detected by either antibody or antigen tests. Testing for viral nucleic acid is the earliest way to detect HIV infection. ...Read more

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Test for syphilis - what do RPR reac and vdrl reac mean?

Screening tests.: Vdrl (venerial disease research laboratory) tests against anti-cardiolipin antibodies and RPR (papid plasma reagin) tests against nonspecific antibodies suggestive of syphilis and are screening tests. Treponemal antibody tests, like fta-abs and mha-tp usually become positive two to five weeks after the initial infection. These are used to confirm syphilis and stay positive, even after therapy. ...Read more

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What causes a false positive for chlymydia pap smear?

What causes a false positive for chlymydia pap smear?

A rare testing error: A false positive occurs when the test is wrong. The chlamydia tests in current use are accurate about 99% of the time. ...Read more

Dr. Hunter Handsfield
535 doctors shared insights

Syphilis (Definition)

A sexually transmitted infection that can cause serious health problems if ...Read more