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Doctor insights on: Sentinel Node Biopsy

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Sentinel Node Biopsy (Overview)

It is first node to which lymphatic drainage and metastasis from a cancer goes to. A biopsy is a procedure that removes a small piece of living tissue from your body. The tissue is examined with a microscope for signs of damage or disease. Biopsies can be done on all parts of the body. A biopsy is the only test that can tell for sure if a suspicious area is cancer.


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What is a sentinel node biopsy?

What is a sentinel node biopsy?

Biopsy of lymph node: Lymph nodes are biopsied to see if cancer has spread beyond the primary site. Using a radioactive tracer and dye, the lymph nodes closest to a tumor can be identified and biopsied without having to remove all the potential draining nodes which can lead to complications. Most often done with breast cancer and melanoma. ...Read more

Sentinel Node Biopsy (Overview)

It is first node to which lymphatic drainage and metastasis from a cancer goes to. A biopsy is a procedure that removes a small piece of living tissue from your body. The tissue is examined with a microscope for signs of damage or disease. Biopsies can be done on all parts of the body. A biopsy is the only test that can tell for sure if a suspicious area is cancer.


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What is a sentinel node biopsy procedure?

What is a sentinel node biopsy procedure?

Sentinel node: Injecting a dye, it initially goes to mother nodes or sentinel nodes and from there nurse to whole node basin. Biopsy of these mother nodes save to biopsy or removing whole nodal areas if sentinel node negative. ...Read more

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What is the definition or description of: sentinel node biopsy?

What is the definition or description of: sentinel node biopsy?

Metastatic node: It is first node to which lymphatic drainage and metastasis from a cancer goes to. A biopsy is a procedure that removes a small piece of living tissue from your body. The tissue is examined with a microscope for signs of damage or disease. Biopsies can be done on all parts of the body. A biopsy is the only test that can tell for sure if a suspicious area is cancer. ...Read more

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What is the difference between a regular node biopsy and a sentinel node biopsy?

Little difference.: Think of a lymph node as a small filter. All lymph nodes act as filters. However, certain lymph nodes are the very first filters in line- they are called sentinel lymph nodes. The idea is that if the sentinel node is removed and negative, the chances of other lymph nodes further down the line being positive is small. You take out less nodes and have less complications! ...Read more

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What is the difference between a needle directed biopsy and a sentinel node biopsy?

Size: A needle-directed biopsy means a hollow needle is stuck into a tumor or lymph node, and only the amount of tissue that fits inside the needle is removed. A sentinel node biopsy removes several lymph nodes entirely and the entire lymph node is examined under the microscope. A sentinel node biopsy requires an injection ahead of time to see which nodes are first in the chain of lymph nodes. ...Read more

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Should axillary sentinel node biopsy be done after chemotherapy?

Should axillary sentinel node biopsy be done after chemotherapy?

Usually before.: Sentinel lymph node biopsy is usually done at the time of lumpectomy for breast cancer. The information gained is used in the decision making as to whether adjuvant chemotherapy should be given to increase the likelihood of cure. Rarely, it might be done after chemotherapy if the initial role of chemo was to shrink the tumor to allow surgery (neoadjuvant chemotherapy). ...Read more

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Should I have a sentinel lymph node biopsy to find out if there is spread to the lymph nodes?

Should I have a sentinel lymph node biopsy to find out if there is spread to the lymph nodes?

See specialist: This is an important question to discuss with your dermatologist. If the melanoma is 1-4mm thick, sln biopsy is often recommended. Between 0.7-1mm depends on other features of your melanoma. Since we have yet to demonstrate survival benefits, sln biopsy is still used primarily for staging. That said, discussion with your specialist is essential as each case is different. ...Read more

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Are antibiotics required after a sentinel lymph node biopsy?

Are antibiotics required after a sentinel lymph node biopsy?

No: I would think that generally the answer is no as the type of surgery is minimally invasive. However, the surgeon performing the procedure will make that decision by using his best judgment. ...Read more

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My friend has breast cancer. She says she needs a sentinel lymph node biopsy. What is that?

My friend has breast cancer. She says she needs a sentinel lymph node biopsy. What is that?

Removing a few nodes: A sentinel node biopsy means removing several lymph nodes in the chain of armpit lymph nodes. Blue dye and/or radioactivity is injected into the breast. The first armpit lymph nodes that "light up" are removed and examined for cancer cells. We know that cancer cells travel through lymph nodes in order. If the sentinel lymph nodes are negative, the others are assumed to be negative as well. ...Read more

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O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.

O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.

Yes they are: By now sentinel lymph node are the standard of care for breast cancer surgery and staging, and yes they are very accurate. Node is negative is a very good news that will make the cancer early stage and hopefully cureable ...Read more

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Where is the lymph node located that is sentinel node?

Where is the lymph node located that is sentinel node?

Depends: The sentinel node is not a specific node but rather the node that first receives drainage from a cancer. Surgeons find it by injecting a tracer near the cancer and then seeing which node first takes up the tracer. The location depends on where the tumor is. Sentinel lymph node biopsy is a procedure done by surgical oncologists for breast cancer, melanoma and some other cancers. ...Read more

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Is there a different process other than the dye test to find the sentinel node? My passage is most likely blocked due to two previous surgeries there.

Is there a different process other than the dye test to find the sentinel node? My passage is most likely blocked due to two previous surgeries there.

Lymph node mapping: If a sentinel lymph node biopsy is required in an area of previous surgery, I would recommend using both lymph node mapping performed by nuclear medicine and blue dye in the operating room along with a hand held gamma probe. With both, the chance of locating a sentinel lymph node increases. ...Read more

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What is the risk of lymphedema if only the sentinel node was removed during mastectomy?

What is the risk of lymphedema if only the sentinel node was removed during mastectomy?

With a...: mastectomy alone there will be a risk of lymphedema, with removal of a sentinel lymph node that risk goes up slightly (in my opinion probably negligible). So it's the mastectomy itself that increased your risk. Follow-up with your docs to detect it early. Remember post-op it will be normal to have some swelling. Hope that helped. ...Read more

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Has anyone had their sentinel node out for breast cancer?

Has anyone had their sentinel node out for breast cancer?

Standard staging: The staging of invasive breast cancer almost always involves assessing the axillary nodes as the most likely 1st place cancer cells can be found outside he breast. Today this is dine via sentinel node mapping/bx to identify, remove, and test the first nod in the chain that will predict the status of the rest. On average just over 2nodes-procedure are removed. ...Read more

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What is breast cancer sentinel node micro metastases?

What is breast cancer sentinel node micro metastases?

Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read more

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Success rate for mastectomy retaining flap and nipple no sentinel node invasion stage 1b measures 8mm, margins good except anterior 1.5mm? Must chemo?

Success rate for mastectomy retaining flap and nipple no sentinel node invasion stage 1b measures 8mm, margins good except anterior 1.5mm? Must chemo?

Tumor genetics: You could request a recurrence score which is a genomic evaluation of tumor cell gene s. 2 common tests in U.S. Are oncotype DX and mammaprint. ...Read more

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Is a sentinel lymph biopsy overkill for melanoma?

Is a sentinel lymph biopsy overkill for melanoma?

No: This depends on how thick the melanoma is in millimeters (the breslow depth) and other factors. For melanoma >1mm it is considered standard, for melanoma 0.75 to 0.99, other factors like age or mitotic rate are considered. Less than 0.75 may be 'overkill' but every patient should discuss the risks and benefits with their surgeon. ...Read more

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Does sentinel lymph biopsy for melanoma work well?

Does sentinel lymph biopsy for melanoma work well?

It does: The sentinel lymph node procedure is the most significant prognostic tool for melanoma. It should be performed in the hands of an experienced surgeon such as a surgical oncologist, ...Read more

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Dr. Harinder Gill
2 Doctors shared insights

Biopsy (Definition)

Biopsy is tissue removed by needle or cutting to remove part of a body part. It is usually a small amount of material that is processed by a pathologist. Most of the time it is stained and looked at through a microscope to arrive at a diagnosis. Special processes are done for some tissues or problems. The purpose is to tell what the problem is (diagnosis). ...Read more