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Doctor insights on: Primidone/Phenobarbital Metabolite

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Is gabapentin addictive drug?

Is gabapentin addictive drug?

Neurontin (gabapentin): No, but sudden discontinuation is not advised. ...Read more

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Dr. Dariush Saghafi
14 doctors shared insights

Primidone (Definition)

Primidone is a seizure agent which is a kind of ...Read more


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Can I take primidone while breastfeeding?

Can I take primidone while breastfeeding?

Yes: Caution should be taken if breastfeeding while on this med. Both primadone and a metabolite Phenobarbital will pass to baby and can produce sedation in the neonatal period. Relative transfer <9% of mothers dose, with serum levels from trace to <1/2 therapuetic for both. Harriet lane c2-caution, hale L3 moderately safe. See medications and mothers milk 14ed. Hale, 2010. ...Read more

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Why phenytoin considered nonsedative antiepileptic?

Why phenytoin considered nonsedative antiepileptic?

Phenytoin: Not sure what you mean. Phenytoin is not considered to be a sedative by definition. This stands for the fact it doesn't possess properties that inhibit the brain in such a way as to induce relaxation, drowsiness, somnolence, calming. ...Read more

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Is tizanidine addictive?

Is tizanidine addictive?

No: But like all medications, take with medical supervision, and follow the instructions on the bottle. ...Read more

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What benzodiazepine is stronger: klonopin (clonazepam) or ativan (lorazepam)?

They differ: Klonopin (clonazepam) is longer acting but takes just slightly longer to start working. Ativan works quicker but clears from your system quicker then Klonopin (clonazepam) although it can stay in your system for a while. ...Read more

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Does hydroxyzine HCl boost the opiate drug effect?

Does hydroxyzine HCl boost the opiate drug effect?

Apparently, yes.: Hydroxyzine is used with opioid analgesics to increase their pain-killing ability of a given dose of opioid, and lower the quantity needed to stop a given level of pain, and/or stop some side effects of opioids like itching, nausea, and vomiting. ...Read more

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Can you tell me about beer and barb and phenobarbitals?

Can you tell me about beer and barb and phenobarbitals?

Dont understand ?: Barbiturates are older sedatives that are very dangerous and are no longer widely used, since they have severe addiction/overdose risk. Phenobarbital is still a useful drug in treating seizures and a few other neurological conditions, and butabital is used in migraine medication. They do not mix with alcohol, whether beer or any other form, and the combination is very dangerous and can kill you. ...Read more

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Is hydromorphone 8mg > 30 mg oxycodone? Orally< which medication is more effective?

Is hydromorphone 8mg > 30 mg oxycodone? Orally< which medication is more effective?

It's all about dose: Hydromorphone 8mg oral is equivalent to approximately 24mg oxycodone oral. Both can be equally effective in an appropriate dose and schedule. ...Read more

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Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Why is chlordiazepoxides, diazepam, clofibrate, barbiturates contraindicated in renal failure?

Impaired elimination: All drugs that are taken are eventually metabolized and eliminated from the body. Although liver enzymes perform the bulk of metabolizing of these agents, elimination of the drug and their metabolites relies, to varying degrees, on the kidney. If the kidneys are failing, elimination is impaired, and a toxic buildup of the drug and/or its metabolites is possible. ...Read more

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How long is ativan (lorazepam) detectable in a urine drug screen?

How long is ativan (lorazepam) detectable in a urine drug screen?

Less than a week: Typically this drug is not detectable by the urine drug screen after 4 to 5 days. It depends on the condition of your liver and if other drugs are present and competing for metabolism. It also depends on the sensitivity and specificity of the test itself. Hope this helps! ...Read more

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Effect of darvon-n tablet(propoxyphene napsylate)?

Effect of darvon-n tablet(propoxyphene napsylate)?

Off market: The drug was pulled off the market in the us last year due to adverse cardiac effects. ...Read more

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Which one is stronger: hydromorphone HCl 8mg or oxycodone HCl 30mg?

Which one is stronger: hydromorphone HCl 8mg or oxycodone HCl 30mg?

Neither: those are close to what most tables would consider equipotency, where hydromorphone is about 3 times more potent than oxycodone. However, there is a huge amount of individual variation in what the equivalent potencies are in different people, as well as in the potential side effects of the different opioids. You should be asking your physician or pharmacist these questions. ...Read more

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Is ativan (lorazepam) addicting?

Is ativan (lorazepam) addicting?

Yes: Ativan (lorazepam) is a benzodiazipine, this class of meds can be addicting, even small doses used over an extended period of time can be very difficult to stop. Some people take them as prescribe and find it very hard to stop, others can be more overtly addicted and continue to take higher and higher doses. In general best for short term use only. Try to avoid if history of addiction like alcohol. ...Read more

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Dr. Andrew Ho Dr. Ho
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Is klonopin (clonazepam) more potient than valium, 4 myclonic seizures?

Dr. Andrew Ho Dr. Ho
2 doctors agreed:
Is klonopin (clonazepam) more potient than valium, 4 myclonic seizures?

Klonopin (clonazepam) more potent: If potency is defined as effect per mg. More importantly, Klonopin (clonazepam) has longer duration of action, which is generally means better coverage for seizure control. ...Read more

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Which is better, librium vs xanax (alprazolam)?

Which is better, librium vs xanax (alprazolam)?

Both: Both of these medications are antianxiety medications. Which will be most effective for an individual depends on many factors. Consult your doctor about which might be best for you. ...Read more

Dr. Jeffrey Stevens
13 doctors shared insights

Mysoline (Definition)

Mysoline is a seizure agent which is a kind of ...Read more