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Poor correlation: Hi. Oral cortisol (aka hydrocortisone) does not reliably affect ACTH secretion nor aldosterone levels. That is somewhat unfortunate for those of us treated adrenal insufficiency, since determination of proper dose is based solely on clinical response, and not labs. Aldosterone is driven by the renin-angiotensin system bypassing the pituitary. UIHC is excellent, so you have great docs close at hand ...Read more
Yes: Glandulars have been a traditional source of these hormones, but there absorption is not realiable. Check with your doctor or check out acam which is an organization that has investigated and held standards on hormone supplementation. They even have a physician referral on there website. ...Read moreSee 1 more doctor answer
Hormones: A tropic hormone is a hormone secreted by one gland and then stimulates another gland; for example, the pituitary makes TSH, which targets the thyroid and causes the thyroid to make T4 and T3 (liothyronine). The thyroid hormones (T4, T3 (liothyronine)) target other organs (heart, CNS, GI, etc), but not really other glands, so are not really tropic hormones. ...Read more
Adrenal gland: yesGet a more detailed answer ›
Enlarged pituitary, no adenoma. Neurological endocrine system disregulation incl. fluctuating thyroid hormone w/goiter (when high). High urine pH 9.0.
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ACTH ALDO Cortisol: I have seen two families in which ACTH is the major driver for aldo production. They have the syndrome called GRA (Glucocorticoid Remedial Aldosteronism) caused by a cross over mutation in the genes controlling aldo production so that the major controller of aldo is ACTH. As you are young and making this question if you also have HTN your team should consider this. Many do not have low K. ...Read moreSee 1 more doctor answer
What pituitary hormones cause the adrenal gland to produce mineralocorticoids, glucocorticoids, and androgens and estrogens including pregnenolone?
Pituitary & steroids: Hi. Pituitary ACTH regulates adrenal cortisol production; it also acutely stimulates aldosterone, but is not the principle regulator. LH principally stimulates gonadal steroid hormone production (both genders make androgens & estrogens, but in opposite dominance). Pregnenolone is early in the steroidogenic pathway in both adrenals and gonads. Good luck! ...Read more
Yes: Should there be loss of adrenocortical function, steroid replacement is advocated to rebuild the normal stamina. ...Read more
Adrenal Insufficient: Acth is a pituitary hormone which stimulates the adrenal gland to secrete cortisol, a hormone necessary for life. When you no longer make acth you get adrenal insufficiency and have to take medication to replace the cortisol. Acth deficiency is often associated with other pituitary hormone deficiencies for which patients are screened. ...Read more
Test adrenal fxn.: This test is to check on whether or not your adrenal glands are working right. The acth action is to increase production and release of corticosteroids. In the test, a small amount of synthetic acth is injected and the amount of cortisol the adrenals produce in response is measured. This is used to check for things like primary and secondary adrenal insufficiency, and addison's disease. ...Read more
Could: ACTH producing pituitary adenoma may cause psychiatric symptoms due to elevation of steroids. A large adenoma may impinge on brain structure and cause mental symptoms. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. Get HPV vaccine. ...Read more
43 yo f, afternoon cortisol high, cortisol suppression test high, CT of adrenal glands normal. Other causes of elevated cortisol?
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- Low cortisol caused by pituitary failure
- Does mri of pituitary gland always show a tumor causing low acth and low cortisol?
- Cortisols effects
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- Hypersecretion of cortisol
- Overproduction of cortisol
- Free cortisol
- Total cortisol
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