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Doctor insights on: Multiplex Ligation Dependent Probe Amplification

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Please interpret- C.trachomatis RNA TMA Result: Detected. Standard range: Not detected. Test performed using the Aptima Combo2 (R) assay gen-probe(r)

Please interpret-
C.trachomatis RNA TMA Result: Detected. Standard range: Not detected. Test performed using the Aptima Combo2 (R) assay gen-probe(r)

You have chlamydia: "Detected" means the test found chlamydia -- i.e. a positive result. Return to the doctor or clinic where the test was done for treatment. (If you tested yourself at a lab, see a doctor or clinic ASAP.) Your current or recent sex partner(s) also need treatment. Good luck! ...Read more

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Male 57, hepatitis C antibody result says reactive 14 with cutoff of 1 . Test performed byy ECLIA . How much chance of false positive. Prognosis?

Male 57, hepatitis C antibody result says reactive 14 with cutoff of 1 . Test performed byy ECLIA . How much chance of false positive. Prognosis?

Check viral load: Even when people have high titer hepatitis c antibody responses, some do not have active infection because their immune system cleared their virus on their own. So the first step is to check a hcv viral load (rna). If the virus is detected in the blood then you do have active infection. At that point you need testing to see how much liver scarring (fibrosis) you have. Work with a specialist. ...Read more

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What individual fetal measurement holds accuracy (represents true gestational age) longest in pregnancy (fl, ac, bpd, hc)?

What individual fetal measurement holds accuracy (represents true gestational age) longest in pregnancy (fl, ac, bpd, hc)?

Must use averages: I don't believe that any single measurement is most accurate throughout pregnancy. It is usually the averages that are taken. The most accurate measurements are actually in the first trimester in the way of the crown rump length in terms of predicting the estimated date of delivery. ...Read more

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Does noninvasive prenatal testing(cfDNA )capture baby's genetic defects?Is amniocentesis better for more accurate results? Im 31&12 weeks pregnant.

Does noninvasive prenatal testing(cfDNA )capture baby's genetic defects?Is amniocentesis better for more accurate results? Im 31&12 weeks pregnant.

Some and yes: The cf-DNA can detect many genetic anomalies but it is not 100% and when positive is usually confirmed by an amniocentesis for a full karyotype. The amniocentesis is the gold standard for detecting genetic anomalies . Sampling of the placental tissue _ ie: chorionic villus sampling would be comparable to an amniocentesis and can be performed earlier in the pregnancy. ...Read more

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Clarivein (better?) vs. Venefit since: simplified access, no tumescence, no concern nerve damage(no rf), but need avoidance of catching of vein wall?

Clarivein (better?) vs. Venefit since: simplified access, no tumescence, no concern nerve damage(no rf), but need avoidance of catching of vein wall?

No in most instances: If you are looking for a method of vein treatment with no tumescence & minimizing nerve damage risk, I prefer Venaseal vein glue . . . it is superior to the clarivein device. Yes, with clarivein there is some risk of catching the vein wall & the catheter no longer spinning properly. In above knee anatomy I prefer venefit over clarivein. In below the knee anatomy prefer Venaseal to avoid nerves. ...Read more

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I had a tubal ligation 6 months ago but dr didn't tell me what kind of procedure he did and if it was an easy reversal what procd.Do dr use more?

I had a tubal ligation 6 months ago but dr didn't tell me what kind of procedure he did and if it was an easy reversal what procd.Do dr use more?

Hard to say: Easiest way to know is ask your doctor or request your operative records. If you had the tubal ligation within days of delivery or during cesarean delivery, the tubes were likely tied and cut. If it was performed later via laparoscopy, then they may have been cauterized (burned), or a clip or ring may have been placed to block the tubes. Procedure choice is highly physician dependent. ...Read more

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Which is least invasive of rf procedures for the patient, re: venefit targeted endovenous therapy vs. Vnus closure system for varicose veins?

Which is least invasive of rf procedures for the patient, re: venefit targeted endovenous therapy vs. Vnus closure system for varicose veins?

Veins: All are equally minimally invasive All have similar outcomes All are tolerated well It's more related to the procedure your treating physician does ...Read more

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For high risks patient desiring future pregnancy (repeated c-section), what is preferred uterine suture? Single v double layer? Locking v nonlocking?

For high risks patient desiring future pregnancy (repeated c-section), what is preferred uterine suture? Single v double layer? Locking v nonlocking?

Surgical technique: Despite its current internet popularity there is no evidence to support a double layer over a single layer uterine closure. Locking sutures are used to stop bleeding (such as the incision in the uterus). Running suture (not locked) are used to bring back non-bleeding tissue layers together. This is Surgery 101. If you are having to explain this to you your doctor it is best to find another. ...Read more

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What is the purpose of av fistula ligation, and what is a possible diagnosis?

What is the purpose of av fistula ligation, and what is a possible diagnosis?

AV Malformation?: Depending on the location, an abnormal communication between arteries and veins can have many different symptoms. The purpose of correction is to alleviate the symptoms. In most cases, the aim is to stop possible deadly bleeding. If this is related to your sudden abdominal pain, then tests should confirm it. If it is related to headaches and one is found, it should corrected immediately. ...Read more

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Can comprehensive chromosome screening (CCS) in IVF screen for (1) partial trisomy, (2) unbalanced translocation, and (3) balanced translocation? Does testing parental karyotyping before CCS help?

Can comprehensive chromosome screening (CCS) in IVF screen for (1) partial  trisomy, (2) unbalanced translocation, and (3) balanced translocation? Does testing parental karyotyping before CCS help?

Test for Aneuploidy: Aneuploidy is the term used to describe any embryo with either too many or too few chromosomes. It is the cause of greater than 60% of miscarriages, as well as the most likely reason that patients do not get pregnant from an IVF cycle. The purpose of CCS is to analyze, select and transfer only embryos that do not have abnormalities in their number of chromosomes. A genetic consult is needed; ...Read more

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How does rubber band ligation work?

Tubal ligation: This is a surgical procedure performed under anesthesia by laparoscopic surgery using band-aid size incisions. Abdomen is inflated with carbon dioxide...You are asleep. The surgeon can see inside your abdomen with a highly specialized 'telescope'. A small silastic band is placed around a 'knuckle' of each tube, the ends seal off and separate, thereby creating a blockage which prevents conception. ...Read more

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+ gonorrhoeae DNA amplification test, but, neg. Amp RNA test(source urine). Do they have gonorrhoeae? Is one test more reliable?

+ gonorrhoeae  DNA amplification  test,  but, neg. Amp RNA test(source urine). Do they have gonorrhoeae? Is one test more reliable?

Complicated: Although these tests are very sensitive there are false positive results because of the potential presence of other benign species of neisseria. If you had to compare the two it would be without much relevant data. Bacterial culture will provide both a definitive diagnosis and allow determination of antibiotic sensitivities. ...Read more

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Wb-band 41 positive, dfm showed spirochetes and gemmas.Syphilis-negative.Can it be Lyme with only band 41 positive?Got inactive demyelination lessions

Wb-band 41 positive, dfm showed spirochetes and gemmas.Syphilis-negative.Can it be Lyme with only band 41 positive?Got inactive demyelination lessions

Possibly- more tests: A 41 band alone could signify lyme but is not enough to make the diagnosis. Unfortunately most labs don't do an adequate WB test- it's crucial to test the highly specific 31 & 34 bands & most labs don't. Ignenex does the best test. See http://www.Ilads.Org/lyme_disease/about_lyme.Html consider the controversial culture from advanced laboratory services: http://www.Medscape.Com/viewarticle/778482. ...Read more

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HSV 1 positive through blood test =[LIAISON assay using chemiluminescence immunoassay (CLIA) tech.] Index=1.47, how likely is it false positive?

HSV 1 positive through blood test =[LIAISON assay using chemiluminescence immunoassay (CLIA) tech.]  Index=1.47, how likely is it false positive?

Not false positive: False positive tests for HSV1 are very rare. Half of all persons your age have positive tests, so nothing unusual there. Most likely from an oral infection in the distant past. ...Read more

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