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Doctor insights on: Metastasis

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Metastasis (Overview)

A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site is called a metastasis.


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What are metastasis?

What are metastasis?

Metastasis: Is when a cancer spreads from 1 part of the body to another part. ...Read more

Metastasis (Overview)

A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site is called a metastasis.


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What's a metastasis?

Metastasis = spread: Metastasis refers to the spread of cancer to area(s) of the body not contiguous with the original cancer, often other organs such as lung, liver or bone. This means the cancer has "spread". ...Read more

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How can metastasis occur?

How can metastasis occur?

3 factors: The tumor must produce matrixmetalloproteinase (MMP) to allow entry into the blood stream. The MMP must breakdown -cadherin to small e cadherin for progression of tumor growth and new cells invading circulation must express a surface antigen that determins site of implantation. Ovary spread to omentum where TGF beta present, Colon to liver because matrix contains liver ferritin. ...Read more

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What does a drop metastasis mean?

What does a drop metastasis mean?

unusual term!: It is something, used when there is a tumor in a lower organ(like in ovary) when the starting organ is located high up in the abdomen, like it can be from stomach cancer. But it is not always an exact term in its causation. ...Read more

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What is the cascade of metastasis?

Describes the biolog: Metastases is a complex process with many steps(often called cascade) that cancer cells released from a primary cancer go thru to reach and establish as distant metastases. ...Read more

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How many types of metastasis present?

Cancer spread: Metastasis means that the cancer spread to a different location via the blood, lymphatics, or other means. Cancer can go almost anywhere in the body depending on where it started. ...Read more

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What is the definition or description of: metastasis?

Metastasis: A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site is called a metastasis. ...Read more

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Are multi spinocelluar ephiteliomas sign of metastasis? Thanks

Metastases from what: Assuming you mean SQUAMOUS CELL CARCINOMA, your question makes no sense without details. Does "multi" mean 3? More? How many? All at once or over some years? Are they in areas exposed to sun or radiation? Are they in anal or genital area? Do you have a transplant? On meds? What is your understanding of "METASTASIS"? Evaluation and treatment should be done by a skin specialist. ...Read more

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What's metastasis, and how does it happen? By blood?

What's metastasis, and how does it happen? By blood?

Spread: This can happen in many ways. It can occur through the blood stream, lymph system or by moving through the local tissues. ...Read more

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Barrett's, how long before metastasis becomes dysplasia?

You are mixed up: Barrett's can be associated with dysplasia of varying degrees. If you have dysplasia, then there is a small risk that it can change into cancer of the esophagus. Your gastroenterologist can guide you if you see him/her regularly for endoscopic examination. ...Read more

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I was wondering what are the molecules associated with invasion and metastasis?

Complex issue: This is an area of research which has many theories but no proven markers. We currently assess this by grade of the tumor and invasivnesss of the vascular and lymphatic strucures as well as invasion of the lymph nodes and the evidence of extra-capsular(extra-nodal) spread of the tumor, all of which suggest a more invasive and more aggressive tumor which will likely recur and spread far and wide. ...Read more

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How can cancer metastasis work?

Different results: Metastasis arises from primary, the former being clonal and the primary, polyclonal. What spreads to a site such as liver or lung can only grow within that parenchyma and never spread elsewhere. The primary has multiple clones each only capable of spreading to a local site and growing there. Thus, primary should always be removed and met focal disease treated later for best survival. ...Read more

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How is colorectal metastasis detected?

CT/surgery.: These are often detected on ct scan, but the most definitive way to detect this is by surgery, often done during resection of primary tumor. This is one reason why the dukes classification is used, as the invasiveness is determined at surgery. Stage a — to submucosa, b — to muscularis, c — to lymph nodes, d — distant metastasis. Organs of metastasis also show signs — liver, bone lung. ...Read more

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What problems are caused by bone metastasis?

What problems are caused by bone metastasis?

Pain: Pain is by far the most common symptom. Less commonly, a fracture may be the cause for discovery and rarer still paralysis from spinal cord compression with vertebral involvement. ...Read more

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How are a cancerous tumor and metastasis different?

How are a cancerous tumor and metastasis different?

Cancer & metastasis: Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems. When these cancer cells spread beyond the primary organ- we call this metastasis. ...Read more

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Is it possible for someone to live with liver metastasis?

Yes: Some people with liver metastasis may be cured of their cancer under certain circumstances. Otherwise, there are treatment options to prolong survival. These include local treatments directed at the liver, as well as systemic chemotherapy. The majority of people with liver metastasis, however, unfortunately will ultimately die of the cancer. ...Read more

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How would angiogenesis influence tumor growth and metastasis?

Fundamental!: All living things need a blood supply to deliver food, water, and get rid of waste. A circulating cancer cell needs to evade detection, get out of the blood vessel, and establish that blood supply: angiogenesis!. All these actors under molecular control, and likely normal during in utero development. Cut off the blood supply, choke the tumor. ...Read more

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How long would someone have to live if their cancer is metastasis?

How long would someone have to live if their cancer is metastasis?

It varies : This is often a very difficult, if not impossible, question to answer for patients. Knowing someone's cancer type and stage and overall health, we can look at statistics of comparable patients and provide estimates of response to therapy, but this is, at best, an educated guess. Statistics are for populations, not for individuals--what does someone look like who has "70% survived" a cancer? ...Read more

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What is metastasis and at what stage of cancer would it start to occur?

What is metastasis and at what stage of cancer would it start to occur?

Cancer spread. : Metastasis is the spread of cancer from the place that it formed to other organs in the body. This usually is a bad sign prognostically, indicating more aggressive behavior. Some cancers can metastasize early, and others rarely do. The "stage" of cancer is determined by multiple factors, depending on the type of cancer. The presence of metastases often means a higher stage, worse prognosis. ...Read more

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Help please? What is the standard dignostic test to confirm cancer metastasis?

Help please? What is the standard dignostic test to confirm cancer metastasis?

PET scan: It depends on the type of cancer whether it is visible on pet scan. Most of the time a ct chest/sbdomen/pelvis will detect abnormalities, and if the abnormality is greater than 1 cm a pet scan will find it. ...Read more

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Could you tell me what is the standard dignostic test to confirm cancer metastasis?

Could you tell me what is the standard dignostic test to confirm cancer metastasis?

None: There is no standard. Depends on the type of cancer and where you are looking for it. A simple x-ray may be sufficient in some cases whereas others may need a ct, pet, mri, or even a biopsy to confirm it. ...Read more

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How is it determined that two cancers in body are a genuine Metastasis case and not two individual cancers?

How is it determined that two cancers in body are a genuine Metastasis case and not two individual cancers?

Cancers : If they are both biopsied, it is easy to tell, by the tissue types. If they are not biopsied, your doctor is most likely going by clinical experience. Good luck. ...Read more

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What is the prognosis for metastasis to bones?

Depend on the cancer: The prognosis will depend on the type of cancer that you have. The presence of metastases to the bone indicate that this is an advance stage of cancer (stage iv)- in majority cases of cancers this is treatable but unfortunately is incurable.
However, prognosis in testicular cancer is still good eventhough the cancer has spread to other organ.
Discuss with your oncologist in detail re prognosis. ...Read more

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What are the common areas of metastasis of melanoma?

Local and distant: Melanomas, like other cancers, can metastasize either locally or distantly. Local metastasis usually means to a lymph node in the area of the primary tumor. From there, other areas which commonly develop metastasis include the lungs, liver, and brain. However, metastases just about anywhere in the body are possible. ...Read more

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What happens if cancer metastasis to the lungs?

Tumors can: Go to the lung substance, or to the lining of the chest cavity. As the tumor expands or fluid accumulates, it crowds out the abilty of the lung to do its job, and shortness of breath, oxygen starvation occurs. Removing fluid, and treating with systemic therapy can slow progresson. ...Read more

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Do benign tumors spread through metastasis?

Do benign tumors spread through metastasis?

No: Benign tumors do not spread to other parts of the body. ...Read more

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How can one stop cancer of the neck metastasis?

How can one stop cancer of the neck metastasis?

Depends: Cancers of the head/neck can spread to the other neck, lungs, bones, liver, etc. Depending on the type and stage surgery initially can be appropriate. Many times use of combined chemotherapy and radiation is helpful. ...Read more