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Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read moreSee 1 more doctor answer
Seizures mouth ulcers hepatocellular disease low blood count anticardiolipin antibodies 1:80 speckled ANA osteoarthritis spine Si joints LUPUS maybe?
Autoimmune disorders: like Rheumatoid Arthritis, diabetes & thyroiditis have an ^ed incidence in children with Down Syndrome (DS). A normal Free T4 & ^ed Ultrasensitive TSH indicates sub-clinical HYPOthyroidism that can become clinical. Macrocytosis, large RBC's, in infants with DS remains lifelong in 2/3rds. It can be associated with anemia from low Vitamin B12 & Folate (folic acid) or iron levels, hypothyroidism or leukemia. ...Read moreSee 1 more doctor answer
Positif ANA IF, Anti-B2 glicoprotein igM, anti-CMV igG, Lupus Anticoagulants, history of DVT. Dr suspect Antiphospholipid Syndrome (APS). Possible?
My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?
Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?
Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read moreSee 1 more doctor answer
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
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