Doctor insights on:
I have recurring flares of rashes, joint pain, muscle aches, debilitating fatigue, dizziness. I have photosensitity and one episode of my WBC at 2.0 years back. My ANA is 6:40. I'm on plaquenil. Why are all my other antibodies neg for lupus?
Maybe SLE maybe not.: Diagnosis of rheumatologic disease is generally based on symptoms with support from lab. Sounds like you have a rheumatologic disease and are being treated with a rheumatologic agent perhaps by a rheumatologist. They can explain your particular situation better, but suffice it to say tests are not always right and a single test does not generally make or break a diagnosis. ...Read more
RA and lupus antibod: If the arthritis looks like RA and the RA antibodies are negative, the disease usually is less erosive and less distrctive to joints and can acrue more symptoms and signs of lupus. If the rheumatoid factor or ccp are positive, that makes the disease act more like ra. ...Read more
I have a hard, red, sore lump in between leg and vagina for about 7 days. Poked it but no pus, little clear liquid and blood. Fatigue/achiness. Have fibro, inflammatory arthritis and lupus antibodies.
Depends...: Patients who only have lupus anticoagulant or other anti-phospholipid antibodies should not be routinely anticoagulated with warfarin unless they have had a clot. Patients who have not had a clot are best off just taking a baby Aspirin daily. If you have not had a blood clot but you are being prescribed warfarin for just having antibodies, seek a 2nd opinion by another rheumatologist. ...Read more
I got a positive lupus antibody test in june and was told I would need lifelong warfarin. Is this accurate?
If all you had was one positive lupus antibody test, then that is not an indication for treatment with warfarin. To make a diagnosis of antiphospholipid syndrome requires multiple positive tests over time in addition to a clinical finding such as a blood clot or miscarriages.
http://www.rheumatology.org/practice/clinical/patients/diseases_and_conditions/antiphospholipidsyndrome. Asp. ...Read more
Could my lupus antibody labs be altered (lower the antiboy level) by me being on 10 mg prednisone.? I'll be on day 3 when labs are drawn. Is it best to be off duing labs?
See below: Lupus anticoagulant (la) is an immunoglobulin that binds to phospholipids and proteins associated with the cell membrane. The disease name is a misnomer. La is actually a prothrombotic agent. The presence of la antibodies precipitates the formation of thrombi. The name derives from their properties in vitro, since in lab tests la causes an increase in clotting time. ...Read more
Depends: The lupus anticoagulant (la) is a screening test for anti-phospholipid antibody syndrome. (apas). Apas includes sometimes severe blood clotting of the arteries and veins. Women with apas sometimes have multiple miscarriages. Some but not all apas patients have lupus (sle). There are false positive la tests: infection and if the test is taken when patient is on an anti-coagulant such as heparin. ...Read more
How risky is attempting pregnancy at the age of 40, mild lupus, antiphospholipid antibody syndrome currently taking coumadin (warfarin)?
Risks: The risks as you describe them, are many, but they are not insurmountable. First, having a baby at 40 is more of a health hazard than having a baby at 20. This might be the biggest hurdle. Second, any chronic disease must be well controlled. Lupus should be quiet before attempting pregnancy. Third, any medications should be reviewed - you are likely aware that warfarin causes birth defects. ...Read more
I have lupus anticoagulant antibodies (aps). Do I need to worry about bein on coumadin (warfarin)?
No: You should be on Coumadin (warfarin) to prevent clots. ...Read more
If I have mixed connective tissue disorder with the lupus anticoagulant antibody can I take nsaids?
Yes: The real question is should you be on long term anticoagulation. If you have had a pulmonary embolis, stroke or heart attack, the answer is usually yes andyou might need to treat simultaneously with aspirin, coumadin (rat poiison) and heparin. Sometimes a very tough disease tocontrol. ...Read more
Are any of the new anticoags useful for factor v leiden and lupus anticoag. Antibody. On lovenox (enoxaparin) 100mg bid. Venous and arterial clotting and pes.?
Maybe: The newer medications to prevent blood clots are not approved for use in the us for your condition. There is published research in europe showing that these medications can be used effectively for your type of problem. My personal bias is that you should wait until more research has been done. Your doctor can help advise you as to the status of this research as it evolves. ...Read more
No: People with lupus anti coagulant can get blood clots and Coumadin (warfarin) is used to prevent them. ...Read more
Is my bruising, burning/stinging at injection site normal-am I doing something wrong? Lupus anticoagulant antibody disorder-history of DVT and pe's.43 yrs old. Have been on new subq enoxaparin-100mg/ml twice daily for 3 days. Pain lasts at least an hour, ha
LMWH: You should be on treatment doses of Lovenox (enoxaparin) at 1mg/kg SQ twice daily if you have suffered a recent DVT and have lupus anticoagulants and use Lovenox (enoxaparin) as a bridge to warfarin. It is normal to feel injection site pain with treatment doses of Lovenox (enoxaparin). I instruct my patients to give "Lovenox (enoxaparin) in the love handles" and alternate sides, in addition to putting ice at the site for 5 min before injecting ...Read more
When they draw blood work to check for imflamation what could they be looking for? Lupus? Anti fospholipid antibody syndrome?
I have aps. My doc says I would have to be off Coumadin (warfarin) for several weeks to be tested for lupus anti-coagulant antibody. How do I know if I have it?
Yes: A girdle should not present any issues. ...Read more