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Doctor insights on: Low T4 And Hig T3

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My ths levels are low (0.05) and my T3 (liothyronine) is 6.5 all so my T4 is 20.2, what medicine do I need to take?

My ths levels are low (0.05) and my T3 (liothyronine) is 6.5 all so my T4 is 20.2, what medicine do I need to take?

Low TSH, High T3/T4: A low TSH with elevated T3 (liothyronine) and T4 defines hyperthyroidism.
This condition is caused by several causes including autoimmune, overactive thyroid nodule, or thyroiditis
further evaluation and testing is needed, to include thyroid scan. ...Read more

Dr. Jesse Krakauer
460 Doctors shared insights

Liothyronine (Definition)

Liothyronine is a thyroid agent. ...Read more


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High T4 and low T3 (liothyronine) after complete thyroidectomy. Currently take 200mcg of levethyroxine. Should I increase or cut my dose?

High T4 and low T3 (liothyronine) after complete thyroidectomy. Currently take 200mcg of levethyroxine. Should I increase or cut my dose?

Depends: Levothyroxine is t4. T4 is converted to t3 (liothyronine), (liothyronine) the active thyroid hormone. Some patients have trouble converting T4 to t3 (liothyronine) and need t3 (liothyronine) replacement inaddition to T4 replacement. You should talk to your doctor about your levels. Depending on the reason for your thyroidectomy, like thyroid cancer, you may want to have higher T4 levels to suppress your tsh. ...Read more

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My body temp is very low, once @ night 95.7. Daytime temp is 96 - 97.3. What gives? T4 is normal, T3 (liothyronine) is very low-but within normal range (barely).

My body temp is very low, once @ night 95.7. Daytime temp is 96 - 97.3. What gives? T4 is normal, T3 (liothyronine) is very low-but within normal range (barely).

Temperature: The magic number of 98.6 is a range a temp can range from 95 to 100.6 and still be considered normal go about your life as long as you are symptom free and forget about your temperature. ...Read more

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I've been on levothyroxine for three weeks and almost feel like my symptoms are worse. Both my t4 and my t3 (liothyronine) are low, the most bothersome symptoms ach?

Dosage adjustment: Usually, most cases of hypothyroidism are treated with increasing doses of l-thyroxin until all levels of T3 (liothyronine). T4 and TSH are normalized. This is determined by routine blood testing including checking for anti- thyroid antibodies to rule out autoimmune (Hashimoto's) thyroiditis. ...Read more

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What causes low TSH, low T4 and low T3 (liothyronine)?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, it would have helped to know the actual values. Even though all these parameters may be low, these may yet be in the normal range. ...Read more

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Am I converting to T3 adequately as TSH:15, T4:20 while T3 quite low at 3.9? 1st time T3 tested. (100mcg levo, prev on 125 daily with T4:25 TSH:0.7)

Hypothyroid and T3: If I understand your question, it appears that your TSH is mildly elevated (not sure of your normal range, though). You probably just need a higher dose of levothyroxine. Or maybe you are intermittently taking it with food, which can impair absorption. T4 to T3 conversion is almost never a problem, and you don't need to take supplemental T3. ...Read more

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Found out I have low t4, hypothyroid. Is my hypothalamus and pituitary functioning as it should? Will t3/4hormone meds assist in correcting all issues

See endocrinologist: The best test for diagnosing hypothyroidism is a TSH level. If it is elevated, you have primary hypothyroidism and your pituitary/hypothalamus works fine. If your TSH is normal, it is possible that you could have a pit/hypoth problem, but this should be diagnosed by an endocrinologist. Simply putting you on t3/t4 will not help you if you don't have a true thyroid problem. ...Read more

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I have trouble in T3 (liothyronine) and T4 and TSH hormens what does them affect if they are low?

I have trouble in T3 (liothyronine) and T4 and TSH hormens what does them affect if they are low?

Thyroid function: If TSH and T3 (liothyronine) and T4 are all low, then you need to check pituitary function and probably get a cat scan of the brain with contrast to be sure that you do not have a pituitary tumor. Usually if TSH is low, then the thyroid is overactive, and T3 (liothyronine) and T4 will be high. ...Read more

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My T3 (liothyronine) and T4 are low value from normal range i.e. 0.63 and 6.51 and TSH is normal what can I do?

On your way to hypot: The TSH is inversely related to the free T4 and free t3;the fact that your TSH is normal when your free T4 is low tells me that your pituitary gland is not responding. You will have to probably go on some supplementation. See your doctor as soon as possible. ...Read more

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My T3 levels have been low consistently, TSH normal, T4 on the high end of normal. Is the low T3 anything to be concerned about?

Hypothyroid and T3: If the TSH is normal, then that is strong evidence that you are normal. Pituitary TSH responds mostly to T3. If you T3 were too low, the TSH should be high. Indeed, I am not sure why T3 is being measured. There are more problems with the T3 assay than that of T4. This could just be "lab error". ...Read more

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My TSH 3rd generation level came back at 9.490. MY T4 was normal and T3 (liothyronine) was low. Taking 200 mcg. What do these numbers mean?

Still hypothyroid: Not sure how long u have been on thyroid replacement, but if been on 200mcg daily over 6-8 weeks, likely require increase dose. If u have just had u'r medication adjusted the. Repeat TSH usually done in 6 wks; the numbers show that u'r body is still in hypothyroid state and that u'r thyroid gland is making less and less hormone or the T4 is not being converted to T3, (liothyronine) so thyroid medicine needed ...Read more

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My wife's free t3&t4 in normal range but her ths is low, it's 0.04. She've been taking thyroxine sodium 175mg for the past 6 months any recomandation?

My wife's free t3&t4 in normal range but her ths is low, it's 0.04. She've been taking thyroxine sodium 175mg for the past 6 months any recomandation?

TSH: She may be subclinical hyperthyroid. Does she have symptoms of hyperthyroidism? Anxiety, increased heart rate, insomnia? Make sure she gets her thyroid panel checked again. Depending on the results and her symptoms, her physician make readjust the strength down. It takes time to get individuals level. ...Read more

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Cause of constant low T4 free, but normal T4, T3 (liothyronine) and TSH?

Cause of constant low T4 free, but normal T4, T3 (liothyronine) and TSH?

Level of TBG: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, if you have high level of thyroglobulin binding protein (TBG) that will make your total T4 high when free T4 may be low. However, if your TSH is in the normal range, you are not likely to be thyroid deficient. ...Read more

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My tsh is low (.015) and total t3 (liothyronine) t4 normal. What does that mean?

May be normal: This may be normal or you may have borderline hyperthyroidism. you should follow this with your doctor. ...Read more

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What does it mean if my T3 (liothyronine) is low? TSH and T4 totals are normal.

Nothing: First how low is low.

generally T3 (liothyronine) alone does not mean anything. Specially with normal TSH, and T4

that mean your thyroid is functioning well.

check with your doctor. ...Read more

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What does a low normal TSH (1.4) and high T4 (11.1) mean? T3 (liothyronine) is normal.

Subclinical thyroid: Could represent subclinical hyperthyroid or early thyroid disease or lab error. Should monitor this over a period of months to see if there is any change. ...Read more

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Dear sir, it is not good to take only T3 (liothyronine) for low thyroid? And why you prefer T4?

T3 (liothyronine) or T4: T4 is the major thyroid hormone in the blood and a small fraction is also converted to T3 (liothyronine).
T4 is preferred. Adding T3 (liothyronine) tablets adds more cost and limited extra value. Sometimes T3 (liothyronine) is necessary but not often. ...Read more

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I have a low level of t3, (liothyronine) ft3, (liothyronine) t4, and ft4. However I have a high amount of tsh. What does it say?

Hypothyroidism: Ask the doctor who ordered the tests for more details, but I think you need to take thryoid pills. ...Read more

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I have hypothyroidism my t3 (liothyronine) and t4 levels are very very low in 0.1 taking 50mcg of Levothyroxin how much is the right dose for me plz answer?

I have hypothyroidism my t3 (liothyronine) and t4 levels are very very low in 0.1 taking 50mcg of Levothyroxin how much is the right dose for me plz answer?

Need more: B"sdCheck since presumably TSH level (most sensitive blood test for thyroid status) should be very high. Depending on your situation an endocrinologist would get you in range by doubling dose then re test in 2 months (it takes 2 months for thyroid levels to stabilize). Then to get it perfect, usually TSH around 1 - smaller dose adjustment at 2 month intervals. ...Read more

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TSH normal at 1.35 T4 8 (range 10-20) T3 (liothyronine) 5.8 (range 3.2-6.0) what are reasons for low T4 levels when TSH is normal and T3 (liothyronine) high normal?

TSH normal at 1.35 T4 8 (range 10-20) T3 (liothyronine) 5.8 (range 3.2-6.0) what are reasons for low T4 levels when TSH is normal and T3 (liothyronine) high normal?

Hypothyroidism: This likely indicates secondary hypothyroidism, due to problem with your pituitary gland. Normally, if the T4 is low, the pituitary will produce more TSH to try and induce the thyroid glad to produce more T4. However, if there is a problem with the pituitary, then the TSH is either low or normal despite a low T4. Be sure to follow up with the doctor how ordered these tests. ...Read more

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0.70 level of anti-TPO and very low cortisol. T3 (liothyronine) T4 is normal. What could it be? Can it be the cause of recurring gynaecomastia even after the surgery?

0.70 level of anti-TPO and very low cortisol. T3 (liothyronine) T4 is normal. What could it be? Can it be the cause of recurring gynaecomastia even after the surgery?

Anti-TPO Antibody: Is an antibody produced by your immune system that attacks your thyroid gland and causes hypothyroidism. Low cortisol is concerning for adrenal insufficiency and you may need a Cosyntropin stimulation test to evaluate. The majority of gynecomastia tends to be idiopathic or related to medications. There are rare instances of tumors producing hormones that cause the findings. ...Read more

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What does a normal tsh, low T4 and low T3 (liothyronine) mean?

Perhaps nothing: Such tests need to be repeated. If the T4 and T3 (liothyronine) were measured as total T4 & T3 (liothyronine) it may mean only that the binding proteins of thyroid hormone are low. Ask your doctor what was done and his/her interpretation. ...Read more

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Low T3, (liothyronine) but normal TSH and T4. Really tired, cold etc. Family hx of Hyprothyroidism.

Low T3, (liothyronine) but normal TSH and T4. Really tired, cold etc. Family hx of Hyprothyroidism.

Not hypothyroid: If your TSH and T4 are normal then your are NOT hypothyroid. Low T3 (liothyronine) can be due to non-thyroidal illnesses. This is because most of Thyroxine (T4) is made in the thyroid gland but 80% of circulating T3 (liothyronine) is made in peripheral tissues (liver, muscle etc) from the conversion of T4 to the more biologically active T3 (liothyronine). Thus illnesses affecting these other organs or tissue can cause a low T3 (liothyronine). ...Read more

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Hello, I have low free t4 but normal t3 tsh and all other metabolic panels. What could be causing this?

Thyroid: A low free T4 may be important but surely your doctor has discussed this with you.
If this has not happened but you feel OK, relax for a bit.
However, if you really are concerned please have your Primary doctor refer you to an Endocrinologist.

All should go well! Please let me know. ...Read more

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If you have a normal TSH and T4 levels but your T3 (liothyronine) is low do you need to increase levothyroxine?

Depends: The T3 (liothyronine) may be low before you take your medication and isn't necessarily abnormal. If you still have symptoms and the TSH is not in the low part of the normal range then adding more levothyroxine is probably the right thing to do. Some people do not convert enough of the T4 to T3 (liothyronine) and they need to take some T3 (liothyronine) in addition to T4 or take a natural thyroid med like Armour Thyroid or nature-throid. ...Read more

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What can cause low normal tsh, low normal t4 & low t3 (liothyronine)? Can intense exercise effect it? Can diet effect it?

What can cause low normal tsh, low normal t4 & low t3 (liothyronine)? Can intense exercise effect it? Can diet effect it?

Thyroid: Since your tsh and t4 are within normal limits, you probably have normal thyroid status. Exercise should not affect thyroid blood tests but excessive iodine or lack of it in the diet can affect thyroid status. An endocrinologist is best qualified to answer your question, however. ...Read more

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What could cause low t4 with normal tsh and t3 (liothyronine)? Have tested low twice now. Also currently being tested for Cushing's.

What could cause low t4 with normal tsh and t3 (liothyronine)? Have tested low twice now. Also currently being tested for Cushing's.

See answer: To be accurate the T4 measurement should be Free Thyroxine. If that is low with normal TSH it can be due to "Central" Hypothyroidism: something affecting the hypothalamus or pituitary. Pituitary adenomas are the most common cause. In this case the TSH is biologically inactive. ...Read more

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I have recently got very low levels of T3 and T4. My TSH is fine. I gained lot of weight and had a very high stress. Do I need some treatment now?

I have recently got very low levels of T3 and T4. My TSH is fine. I gained lot of weight and had a very high stress. Do I need some treatment now?

Just a thought: But your pituitary may be incapable of increasing the TSH and a "normal" level may actually be due to a lack of proper pituitary function (producing a higher TSH in the fact of low thyroid gland function. I would suggest a PITUITARY evaluation and after that is complete I would treat you with Thyroid replacement therapy!
Hope this helps
Dr Z ...Read more

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Last Nov my t3 & t4 were elevated & my tsh was a bit low so I took methimazole 5mg for a month. I checked my ft4 & tsh after both came normal. Am I ok?

Maybe: I wouldn't self manage, even if I have been through this before, you need to be followed by a doctor, preferably an endocrinologist, thyroid gland is a complex one, and there are more tests needed for evaluation, needs an expert, hope you find one, good luck ...Read more

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Does normal (1.01) "thyroxine (t4) free, direct, s, " normal (0.931) "tsh, " and low (67) "triiodothyronine (t3)" = Synthroid dose good? Or go up/down?

Does normal (1.01) "thyroxine (t4) free, direct, s, " normal (0.931) "tsh, " and low (67) "triiodothyronine (t3)" = Synthroid dose good? Or go up/down?

Thyroid tests: The tsh, and secondarily the ft4, are normally used to guide the dosage of levothyroxine replacement. T3 (liothyronine) is not normally followed for this. There are a number of issues, and you would be best discussing this with your doctor. ...Read more

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MCH slightly elevated at 34 (MCV) normal but on high side is it any relation to low t3 (liothyronine) levels 46? TSH and T4 also low laying but normal range.

Yes: Thyroid T3 (liothyronine) levels affect red cell indices, refer to Dorgalaleh et al article Via web literature which answers your question well. ...Read more

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My TSH is low, my T3 (liothyronine) and T4 normal. Family history (paternal side). Otherwise healthy weight, vegetarian good diet, exercise regularly. Suggestions?

My TSH is low, my T3 (liothyronine) and T4 normal. Family history (paternal side). Otherwise healthy weight, vegetarian good diet, exercise regularly. Suggestions?

Hyperthyroidism: If TSH is low, this indicates higher than normal thyroid function. Normal T3 (liothyronine) and T4 are good, but at this point, I would proceed with radioactive iodine uptake to rule out graves' disease. If this is normal, repeat tsh, if still decreased, then you have subclinical hyperthyroidism. Reconvene with your doc at that point and decide on the next step. He may request specialty consult as well. ...Read more

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My TSH is high end of normal at 0.66, free T4 is 1.3 but my free T3 (liothyronine) is low end of normal at 2.7. Why does my TSH not better correlate with free t3/t4?

My TSH is high end of normal at 0.66, free T4 is 1.3 but my free T3 (liothyronine) is low end of normal at 2.7. Why does my TSH not better correlate with free t3/t4?

Hard to say,,: First, the TSH isn't at high normal, more like low normal (0.4-2.5uiu/ml), next is that the ft4 is at a high normal value. The ft3 is around low normal but it has a low half life so that might be why. You've got a history of hashimoto's which leads to hypothyroidism and take synthesis for replacement which can explain these values so it's good to see your doctor for a possible med adjustment. ...Read more

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Tsh is high end of normal at 0.66, free T4 is 1.3 but free T3 (liothyronine) is low end of normal at 2.7. T3 (liothyronine) and T4 down 1 point in 1 month. Felt better before. Why?

Tsh is high end of normal at 0.66, free T4 is 1.3 but free T3 (liothyronine) is low end of normal at 2.7. T3 (liothyronine) and T4 down 1 point in 1 month. Felt better before. Why?

Normal TSH: They key word is "normal". Your TSH is normal, which means your pituitary believes your thyroid hormone levels are normal, and the pituitary is usually right. You list a number of autoimmune rheumatologic disorders. These may be responsible for your symptoms, rather than your thyroid. See your rheumatologist. ...Read more

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Tsh 1.3 total t4 7.2 free t4 1.33 total t3 60 ng/dl range 71 t 180 Free t3 2.4 my total t3 keeps comming back low. Once it was only 52 and others it was 71 I have symptoms should low total t3 and bottom range free t3 be treated thi

TSH: An elevated TSH level is essential for the diagnosis of an underactive thyroid. Without that finding, despite other borderline findings, thyroid replacement wouldn't be prescribed. A Thyroidologist or endocrinologist is best qualified to evaluate and treat you, however. ...Read more

Dr. David Sneid
1,422 Doctors shared insights

Thyroxine (Definition)

Thyroxine is a thyroid agent. ...Read more


Dr. David Geffner
459 Doctors shared insights

T3 (Definition)

T3 is a thyroid agent. ...Read more