Doctor insights on:
Low Islet Cell Antibody
Is a negative HIV person, diagnosed with low lymphocytes T4 and t8 cells, still able to produce HCV antibodies after 1 year of one possible exposure?
8yoaLow T and B cells, borderline reactive Hep B, Negative Candida, low Pneumococcus antibodies. Referred to infectious disease Dr. What can this be?
?: How is he doing otherwise, what promoted the dr to ask for those tests, is he having frequent hard to treat infections? At any rate could be something temporary, and vaccine non responders are not uncommon, the low T and B lymphocytes can be just part of low lymphocytes altogether for several reasons most are reversible, infectious disease consultant may seek an Immunologist input, goodluck ...Read more
What might cause hyperthyroid, high anti-centromere b antibodies, enlarged red blood cells and high iron saturation, normal serum iron, low TIBC/UIBC?
THIS IS A "LONGSHOT":
But this set of symptoms (SYNDROME) sound like HASHIMOTO's THYROIDITIS and PERNICIOUS Macrocytic anemia also may be AUTO-IMMUNE!!!
In nature ie: the body falsely detects NORMAL TISSUE as being "FOREIGN" and develops auto-antibodies against (in this case) your thyroid gland and your bone marrow)
This is a guess....just a "thought".hope it helps!
Dr Z ...Read more
Will normal antibiotics (ie augmentin) work effectively on someone HIV positive with a low t cell count?
Antibiotics: The effectiveness of antibiotics depends on their activity against the bacteria involved. The antibiotics effectiveness does not depend on the individual's ability to ward off illness (immune competence). So, of the antibiotic being prescribed works against the causative agent, the HIV status shouldn't mean much. ...Read more
Can mirena (levonorgestrel) cause red/white bld cells in urine? Bad low back pn, antibiotics not helping. Doc says UTI but worried mirena (levonorgestrel) moved and causing infection?
Hi my tongue has been green for over a week, I'm taking antibiotics for pleurisy, I also had a flu virus & have low white blood cells?
Low white blood cell count (transfusions required), pelvic infection (no response to antibiotic) Doc suspects autoimmune but stumped. Ideas?
Not autoimmune: rather, could be immunodeficiency, and the low white cell count?can be due to several causes. Immunodeficiency, can be primary or secondary, the latter could be your case, again for a multitude of reasons, overwhelming infection, certain drugs that suppress the immune system, certain viral infections, superbugs, and others. You may need a combination of IV antibiotics and a team approach, good luck ...Read more
When patient has autoimmune flares that cause weeks of glucose intolerance and diabetes-type symptoms that resolve, would it be useful to test for antibodies to gad, insulin or islet cells?
Possibly: Autoimmune diseases tend to occur together, so checking for antibodies for type 1 dm can be helpful to assess for that diagnosis. Glucose tolerance should not fluctuate with a flare in gad/insulin/islet abs. It more likely to be from treatment of the autoimmune flare (steroids) or stress from the flare. ...Read more
Interesting tumor: Overally, neuroendocrine tumors are often capable of over-producing hormones that your body naturally makes. Islet cells are cells that are naturally present in the pancreas and produce a number of hormones, most notably insulin. Insulin helps you break down and digest sugars. Patients with an islet cell tumor can produce too much Insulin resulting & gain and low blood sugars. ...Read more
Islet tx pain : Generally none.Get a more detailed answer ›
Weigh the options: Islet cell transplants are performed, and many patients have been helped by them. In particular, to treat the terrible symptom of hypoglycemic unawareness. Like any surgical procedure there are risks and benefits that should be carefully discussed and understood before you go forward with the procedure. ...Read more
Can you tell me how to find out if the islet cell transplant is for me, or if im eligable for it?
Evaluate carefully : You need to have a careful discussion of your degree of diabetes, and the risks and benefits of the procedure. Find a local transplant center that does the proceed and go over these issues point by point. Procedure itself, results short and long term, medications needed, their side effects, etc. Contact the american society of transplant surgeons for centers in your region. ...Read more
Islet cell tumors of the pancreas represent the second form of lesion, the first representing lesions of ductal origin that lead to the classic pancreatic carcinoma, most frequently arising in the head.
The second group of tumors, those of neuroendocrine origin arise in clustered cells known as islets and which are mainly benign When malignant they spread with a survival of about 5% ...Read more
Difficult to say: Islet cell tumors are rare forms of cancer that arise in the endocrine tissues of the pancreas. They can secrete a variety of hormones, including insulin, glucagon, gastrin, and vasoactive intestinal peptide, resulting in a myriad of clinical syndromes. However, the majority are not associated with a hormonal syndrome, and therefore, yours may have been detected incidentally. I need more info. ...Read more
Form hybridoma: When an antigen is given to an animal, B cells in serum produce a polyvalent antibody prep. When antigen is given to an animal and spleen cells (B) are fused with malignant B cells, a hybrid clone is formed producing monoclonal antibodies to the specific protein antigen. ...Read more
Useful in pregnancy: Rhesus (Rh) factor is an inherited protein found on the red blood cells. If your blood has it, you're Rh positive. If your blood lacks it, you're Rh negative. Rh positive is the most common blood type. Having a Rh negative blood type is not a problem but It becomes important if the mother who is Rh negative develop Rh antibodies, from a Rh+ fetus; as these can cross placenta and cause problems. ...Read more
Infection: Like any infection by a foreign "invader", HIV induces an antibody in an effort to fight back. The issue is that HIV kills T cells, a different type of immune cell. B cells are activated to make the antibody but the antibodies are not strong enough to stop HIV from infecting, replicating inside of and then killing T cells. ...Read more
Homework: Physicians do not do their patients homework for them. Plagiarism is frowned upon in education. Your question would take up an entire chapter in a textbook. Go read the chapter and answer your assignment in your own words. ...Read more
If cells such as T cells and NK killer cells ATTACK organs or neurons but don't produce Antibodies what methods are used to diagnose this?
Clinical diagnosis: Clinical diagnosis by an appropriately trained rheumtologist ...Read more
What's the difference on Antibodies/Antigens on the exterior of the cell vs the interior while testing and worried about the sensitivity/accuracy?
Please Clarify: Your question is very vague. There are thousands of Antibodies and millions of Antigens.if not more. Which in specfic are you interested to find out about. Please think it through what exactly do you want to know? ...Read more
Saving insulin: When an islet cell transplant has to be performed it means that the pancreatectomy was total. The pancreas is an exocrine (digestive juice) and endocrine gland from the Islets of Langerhans. When all are removed, islet transplant helps retain endocrine activity including insulin production. ...Read more
Total pancreas out: Most of the islet cells that produce glucagon and insulin are in the body and distal pancreas so that to have them removed requires a total pancreatectomy. Autologous transplants are being performed at the present time by Dr. Horatio Rilo but if not perfomed. Hormone replacement required as wll as pancratin for digestion. ...Read more
Can work for some: It remains experimental, and there may be some difficulties obtaining insurance coverage, but can work for a number of patients. Islet recipients must take immunosuppressive drugs and therefore are exposed to the toxicities of these agents. A major limitation has been obtaining enough islet tissue; due to loss of islets during preparation, one pancreas may not be enough for one recipient. ...Read more