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Doctor insights on: Leukemia/Lymphoma Evaluation

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Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

Define differential diagnosis of prolymphocytic leukemia or mantle cell leukemia.

They are too differe: There should be no confusion between these two entities. One is a lymphoma(nodal disease) the other one is a blood cancer that should not affect the lymph nodes. Rather easy diagnosis if you are seeing the right type of specialist! ...Read more

Dr. Michael Thompson
1,766 doctors shared insights

Lymphoma (Definition)

A malignancy that develops in the lymph glands that causes nodes ...Read more


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What is lymphoma, and does lymphoma come from leukemia?

What is lymphoma, and does lymphoma come from leukemia?

Kissing cousins!: When a blood cell starts growing out of control in the place where it is 'born', i.e. The blood factory or bone marrow, then it creates a leukemia. When the blood cell is born normally and then moves to the lymph nodes in the body (tonsils, appendix etc) to get educated to function well, but instead grows out of control at that point, then it is a lymphoma. ...Read more

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Could a complete blood count (cbc) determine leukemia or lymphoma?

Could a complete blood count (cbc) determine leukemia or lymphoma?

Not the best way : A blood cell count and blood smear may provide an indication of leukemia, however, diagnosis usually requires examination of bone marrow. Diagnosis of lymphoma usually requires biopsy of the node and examination of the tissue by a pathologist. ...Read more

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Would a CBC help diagnosis leukemia?

Would a CBC help diagnosis leukemia?

Yes it would: Leukemia is a cancer of the white blood cells, so the white blood counts are effected by leukemia, usually they increase but sometimes they can go down too. Also the hb and platelet counts are also affected by leukemia as it grows in the bone marrow and can compromise the production of all types of blood cells.. So a CBC is a good screening test for leukemia diagnosis. ...Read more

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Would a complete hemogram reveal leukemia?

Would a complete hemogram reveal leukemia?

It is possible: the complete hemogram could reveal leukemia or many other less serious problems that can be treated ...Read more

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Differential diagnosis for acute appendicitis?

RLQ Pain: Long list including diverticulitis, crohn's disease, pelvic inflammatory disease, cholecystitis(gallbladder), ovarian cyst or twisted ovary, colon cancer, kidney stone, perforated ulcer, pancreatitis, bacterial infection and urinary tract infection to name a few. ...Read more

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Treatment options for diffuse large b-cell lymphoma?

Treatment options for diffuse large b-cell lymphoma?

R-CHOP: The most common regimen is r-chop (rituximab, cytoxan, adriamycin, (doxorubicin) vincristine, prednisone). Other options are epoch-r, a clinical trial. There are several regimens, but the most common regimen is r-chop. It also varies on the stage of the disease. Hope this helps. ...Read more

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What are the diagnostic tests for acute lymphoblastic leukemia?

What are the diagnostic tests for acute lymphoblastic leukemia?

Bone marrow biopsy : The diagnosis is typically with a bone marrow biopsy, cytogenetics (dna of leukemia cells), and flow cytometry (cell surface markers of leukemia cells). ...Read more

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Can you tell me are leukemia lumps the same as lymphoma?

Can you tell me are leukemia lumps the same as lymphoma?

No: Patients with some types of leukemia can develop lumps or tumors. Today these are called granulocytic or myeloid sarcomas or extra medullary myeloid tumors. In the past they were called chloromas because of their greenish hue when cut open. They are usually not in lymph nodes. Lymphomas generally do not float around in blood to the same degree and the tumors are usually in the lump nodes. ...Read more

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Is polycythemia a consequence of chemo treatment for hodgkins lymphoma?

Is polycythemia a consequence of chemo treatment for hodgkins lymphoma?

Polycythemia: No. See your oncologist or hematologist to discuss various causes and appropriate workup and if needed, therapeutic phlebotomy as a treatment. ...Read more

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Can a complete blood count test diagnose leukemia or other cancers?

Usually leukemia: A CBC with differential can detect features worrisome for a leukemia (high or low white count, anemia, or thrombocytopenia). The automated machine can detect abnormal cells which flags for a technologist and/or pathologist to manually identify and count under the microscope. Then a flow cytometry test may be done to determine the lineage of the cells for the actual type of leukemia. ...Read more

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What causes an inhomogeneous spleen in hodgkin lymphoma?

Lymphoma vs. other: The spleen in hl may be heterogeneous/inhomogeneous/non-uniform due to lymphoma involvement, spleen infarction (death) due to cancer death in the spleen, or infection, or "other". The radiologist may or may not be able to determine that and your oncologist might be able to say more about it with knowing the clinical history. ...Read more

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Would a CBC show lymphoma or leukemia?

Likely for leukemia: Oftentimes leukemias can be picked up on routine CBC since it is a cancer of the blood and causes abnormal values of your red and white blood cells to appear. Lymphomas do not always affect the blood in a way that would be picked up on cbc. All leukemias however will not be picked up on routine CBC and CBC alone will not tell you what kind of leukemia specifically one might have. ...Read more

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Can leukemia or lymphoma be found in blood work from my regular dr?

Sometimes....: For leukemia, you sometimes can detect the leukemia cells on a routine complete blood count (cbc). However, not every lab is good at identifying these cells (called blasts). Lymphoma requires a biopsy to make the definitive diagnosis. There are other lab tests that can make you suspicious of either leukemia/lymphoma, but other specialized tests are needed to confirm. ...Read more

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Dr. Liawaty Ho Dr. Ho
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What causes an inhomogenous spleen in hodgkin lymphoma?

Dr. Liawaty Ho Dr. Ho
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What causes an inhomogenous spleen in hodgkin lymphoma?

Spleen involvement: Spleen involvement from hodgkin's lymphoma can give you heterogeneous/inhomogenous appearance of the spleen in the ct scan. A pet scan will tell you whether this is involvement from hodgkin's lymphoma or rather from other causes. ...Read more

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Whats standard infectious workup post POTS diagnosis? Does typical workup include Lyme disease testing? ,

Whats standard infectious workup post POTS diagnosis? Does typical workup include Lyme disease testing?
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Yes: Lyme can cause autonomic dysfunction including POTS- good idea to get tested for lyme and its coinfections such as bartonella, mycoplasma, erhlichia, anaplasma, babesia and rocky mountain spotted fever which are all tick borne infections ...Read more

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Please describe treatment options for sickle cell disease?

Please describe treatment options for sickle cell disease?

Many: Treatments for sickle cell disease include hydroxyurea, blood transfusions, or even bone marrow transplants in certain cases. It depends on the severity of disease. Treating pain crises is also a very important part of managing the side effects of the disease. Because sickle cell disease can affect many organs in the body, it is essential to receive care from an expert in sickle cell disease. ...Read more

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What is a karyotype for acute lymphocytic leukemia?

What is a karyotype for acute lymphocytic leukemia?

A karyotype is ...: A technique that lets us see the gross structural features of the chromosomes in a cell. Cells are forced to enter mitosis but then are arrested in metaphase with a drug called nocodazole. The chromosomes can the be seen under the microscop which lets is see their number and structure. All cells can have multiple abnormalities that can be seen by karyotype, but may be normal as well. ...Read more

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Dr. Liawaty Ho
1,163 doctors shared insights

Leukemia (Definition)

A cancer of blood-forming tissues, hindering the body's ...Read more