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Doctor insights on: Leukemia

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Dr. Liawaty Ho
1,149 doctors shared insights

Leukemia (Overview)

A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow but in lymphoid tissues.


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How does leukemia affect your lymph nodes?

How does leukemia affect your lymph nodes?

It depends: It depends on the type of leukemia. All leukemias affect your immune system, because leukemia is abnormal growth of white blood cells. In acute leukemia, the tumor cells grow in the blood and usually the lymph nodes aren't enlarged. In chronic leukemia, (cll or cml) the lymph nodes can become enlarged from leukemia cells growing within. ...Read more

Dr. Liawaty Ho
1,149 doctors shared insights

Leukemia (Overview)

A malignant hematologic neoplasm that originates in the bone marrow and represents a clonal proliferation of hematopoietic elements belonging to any of the myeloid, lymphoid, erythroid, and megakaryocytic lineages. Of note, other hematologic neoplasms like lymphoma or myeloma may demonstrate a leukemic phase without actually originating in the bone marrow but in lymphoid tissues.


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What are symptoms of leukemia?

What are symptoms of leukemia?

Symptoms. : When someone had leukemia, it causes specific symptoms. These include easy bruising or bleeding, fatigue, fevers. The leukemia affects the blood counts, typically making blood counts very low. Leukemia may also cause swelling of the lymph nodes, liver and spleen. ...Read more

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What are earlier signs of leukemia?

What are earlier signs of leukemia?

May be few: There may be no symptoms especially with chronic leukemias. Symptoms can include fatigue, easy bruising or bleeding, shortness of breath, fevers, infections and night sweats. ...Read more

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Would a CBC help diagnosis leukemia?

Would a CBC help diagnosis leukemia?

Yes it would: Leukemia is a cancer of the white blood cells, so the white blood counts are effected by leukemia, usually they increase but sometimes they can go down too. Also the hb and platelet counts are also affected by leukemia as it grows in the bone marrow and can compromise the production of all types of blood cells.. So a CBC is a good screening test for leukemia diagnosis. ...Read more

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How do you diagnose leukemia?

How do you diagnose leukemia?

Blood or bone marrow: Typically this s diagnosed by a bone marrow test. In the marrow will be the abnormal proliferation of cells of the same type. At times, these cells in the can "spill" into the blood. When this occurs, the leukemia s diagnosed on blood tests. Even when noticed in the blood, a marrow test is usually performed as well. ...Read more

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What are the diagnostic tests for acute lymphoblastic leukemia?

Bone marrow biopsy : The diagnosis is typically with a bone marrow biopsy, cytogenetics (dna of leukemia cells), and flow cytometry (cell surface markers of leukemia cells). ...Read more

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How much time does it take to get blood test results if leukemia is suspected?

Depends: Sometimes very quickly because you can see the abnormal cells on a slide under the microscope from a simple blood draw. Sometimes it requires a bone marrow biopsy. But even if that is done, once the slide a stained, the pathologist can look right away. Hope this helps. ...Read more

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What are the tests for leukemia, adult acute?

What are the tests for leukemia, adult acute?

Labs,bone marrow : Cbc, review of peripheral blood smear, bone marrow aspiration and biopsy with flow and cytogenetics. ...Read more

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How can you know if you have leukemia?

How can you know if you have leukemia?

Blood test usually: If you have certain symptoms, blood tests will be done which may show leukemia. These tests may not show the leukemia outright. Either way, if there is. Still concern, a bone marrow test will be done. This test will be able to determine if the symptoms are leukemia or not. ...Read more

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What causes leukemia?

Leukemia cause: We don't know for sure. Leukemia develops as the consequence of a series of genetic changes in blood cell offsprings. These changes alter normal growth and differentiation of the cells, resulting in an accumulation of abnormal, immature blood cells in the bone marrow and peripheral blood. Exposure to chemicals, radiation, tobacco, or chemotherapy, infection, etc have been associated with leukemia. ...Read more

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Do bone marrow aspirations mean leukemia?

Do bone marrow aspirations  mean leukemia?

No: We do them for several reasons including evaluation for an abnormal cbc. Sometimes we are concerned about leukemia but the other reasons include the following: anemia, low platelets, staging of lymphoma, monitoring therapy. Hope this helps. ...Read more

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Is adult leukemia treatable and if you have a sibling what are the chances of them being a good donor?

Is adult leukemia treatable and if you have a sibling what are the chances of them being a good donor?

Yes, 25%: Yes, adult leukemia are treatable. The treatment would depend on the type of leukemia, the biology of the leukemia etc. -the formula for calculating the chances of a particular person having an hla-matched sibling is 1 − (0.75)n, where n denotes the number of potential sibling donors.In general, a patient with one sibling has a 25% chance of having a match. ...Read more

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Do you treat leukemia differently in a child than an adult?

Do you treat leukemia differently in a child than an adult?

More intensive chemo: Yes, chemotherapy regimens for pediatric acute leukemia are usually much more intensive and the dose usually is higher than the chemo for adult patients. Children are much tougher than how they look . They get higher dose of chemo and more intensive , but they tolerate them very well and would bounch back right away. ...Read more

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Help! Is it possible to have children if you are being treated for leukemia?

Help! Is it possible to have children if you are being treated for leukemia?

Yes: Ask your oncologist about fertility sparing regimens if you want to have children. There are a variety of ways to spare child bearing ability if you have leukemia from freezing sperm to harvesting eggs to using chemotherapy and radiation that reduces side effects on reproductive organs. Lots depends on your type of leukemia, age, etc. so it important to ask your oncologist for your specifics.... ...Read more

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Are there official recommendations for treating leukemia?

Are there official recommendations for treating leukemia?

Yes: Check nccn.Org, they have guidlines for multiple cancer types including all types of leukemia. ...Read more

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How long is a typical treatment for leukemia?

How long is a typical treatment for leukemia?

Depends on type....: There are many types of leukemia (all, aml, cml, cll) and each have different treatment regimens. Age also plays a factor (adult vs. Pediatric treatment protocols). For example, AML is intensive, but relatively short (~9 months). All can be 3-4 years. CML treatment can be lifelong, though is can be treated with oral pills taken daily. ...Read more

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What are treatments available for leukemia?

What are treatments available for leukemia?

Follow the advice...: Of your hematologist/oncologist. First step is a specific diagnosis, and from there they can formulate a plan of care and address whether there might be a clinical trial that you are eligible for. Once you begin therapy, there will be much to pay attention to, but following protocol directed therapy as closely as possible (with possible mods by your dr) is important. Open communication is key! ...Read more

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How can stem cell transplants actually cure leukemia?

It is one of the bes: Stem cell transplants do indeed cure some leukemias. The procedure requires total body radiation, high dose chemotherapy to kill all blood cells(including leukemia cells) and then we use stem cells to regenerate the normal bone marrow in order to form new healthy blood cells. ...Read more

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How often does a bone marrow transplant not get rid of the leukemia?

Variable: The success rate of a transplant is dependent on many factors: the type of leukemia, some genetic factors about the leukemia, current remission status, prior therapies, type of transplant and other medical problems of the patient. ...Read more

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Effects of leukemia drugs: mylotarg and cytosine arabinoside?

Mylotarg-cytarabine: Open these links:

http://www.Drugs.Com/mtm/mylotarg.Html
http://www.Drugs.Com/mtm/cytarabine.Html.

Get a more detailed answer ›
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How do you know if your child has leukemia or not?

How do you know if your child has leukemia or not?

To see pediatrician: You should bring your child to see your pediatrician and dicuss further with her/him in detail about possibilities. She/he will examine your child and order the necessary initial blood work. If there is anything suspicious then she/he will be able to refer you to see a pediatric hematologist/oncologist for further evaluation/testings i.e. A bone marrow biopsy etc. ...Read more

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Who gets leukemia?

Anyone...: can get leukemia. Rarely some individuals might inherit a familial disposition, and a few occupational exposures may increase risk (radiation or benzene exposure). More often it occurs from a series of random mutations that happens by bad luck in a single bone marrow stem cell. These mutations causes it to increase in number dramatically, pushing out healthy cells, but leaves them under developed. ...Read more

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Is there a genetic component to leukemia?

Is there a genetic component to leukemia?

There can be: But not in the sense that it is inherited within family members. An example is those individuals affected by down's syndrome have an abnormal chromosome and acute leukemia has a higher incidence in this population. ...Read more

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What puts me at risk for leukemia?

Many things: These can increase your risk, but do not mean you will get leukemia: 1. Family history of leukemia 2. Exposure to certain chemicals, eg benzene (found in degreasers) 3. Exposure to high or chronic radiation eg nuclear reactors 4. Previous chemotherapy or radiation therapy 5. Myelodysplastic syndrome 6. Downs syndrome and other genetic diseases 7. Smoking! ...Read more

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Is there any way to prevent leukemia?

Not really: Certainly one can avoid exposure to agents which promote cancer: many of which are outlined in the state of california website where many substances have to be labelled as being possible carcinogens - but other than this..Avoiding exposure to extremely high doses of radiation such as atomic bomb blasts are about the only known things you can do to lower the risk. ...Read more

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How do I avoid developing leukemia?

Nothing: I do not know of anything that can prevent leukemia. A study at mayo clinic by dr. Shanafelt was looking at treating early stage cll with green tea extract. Further studies will likely go forward. Some risk factors, such as prior chemotherapy for other cancers can increase the risk of leukemia, but that is likely not avoidable. I am unaware of any diet or exercise intervention. ...Read more

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What is leukemia?

What is leukemia?

Blood cancer: Generally speaking, leukemia is a form of cancer, more specifically a cancer that usually originates in the bone marrow and then spreads into the blood. There are many different types and subtypes with their own particularities. ...Read more

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Who gets leukemia?

Anyone...: can get leukemia. Rarely some individuals might inherit a familial disposition, and a few occupational exposures may increase risk (radiation or benzene exposure). More often it occurs from a series of random mutations that happens by bad luck in a single bone marrow stem cell. These mutations causes it to increase in number dramatically, pushing out healthy cells, but leaves them under developed. ...Read more

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