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Doctor insights on: Hydroxyurea

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Dr. Margaret Shipp
235 Doctors shared insights

Hydroxyurea (Overview)

Hydroxyurea is a cancer agent.


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What does small amounts of hydroxyurea in blood mean?

What does small amounts of hydroxyurea in blood mean?

Treatment/exposure: Hydroxyurea is a drug used to treat certain blood disorders, some cancers, and HIV disease. If you not on this medicine you may be exposed to it in other ways such as handling it for a loved one. If neither is the case, please consult a healthcare provider asap. ...Read more

Dr. Margaret Shipp
235 Doctors shared insights

Hydroxyurea (Overview)

Hydroxyurea is a cancer agent.


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Can you tell me about hydroxyurea 500 mg availability?

Can you tell me about hydroxyurea 500 mg availability?

Available: 500mg oral tab of hydroxyurea is available in US. Is that your question? . The dosing of hydroxyurea, however, should be monitored by a doctor. ...Read more

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Can we use hydroxyurea with sickle cell anemia patient?

Can we use hydroxyurea with sickle cell anemia patient?

HU in sickle cell: Certain patients with sickle cell can be helped by Hydroxyurea (hu). Initially, Hydroxyurea was thought to increase fetal hemoglobin levels (not carrying the sickle cell mutation), but more recently, hu has been shown to decrease high white blood cell counts which can lead to vaso-occlusive crises. Talk with your hematologist to see if hu is right for you. ...Read more

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Before 2 yrs old is Hydroxyurea safe for a e beta thallassemia child? She needs transfusion after every 45 days. Pls advice...

Before 2 yrs old is Hydroxyurea safe for a e beta thallassemia child? She needs transfusion after every 45 days. Pls advice...

Studies have shown…: Benefits from use of hydroxyurea, even in children aged 2.6 and 3 years. Because of the child's age, I'm going to refer your question to a pediatric hematologist/oncologist. ...Read more

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Can muscle cramping be a side effect of taking hydroxyurea?

Can muscle cramping be a side effect of taking hydroxyurea?

Not commonly: It's not a common symptom of Hydroxyurea but Hydroxyurea can cause nausea, vomiting, diarrhea and renal impairment which can cause muscle cramps. Not sure you have the above symptoms. ...Read more

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How long can a patient take hydroxyurea for primary essential thrombocytosis?

As long as it works: This medication has been studied for a long time. There has been no reported cases of secondary cancers directly related to hydrea (hydroxyurea). It just needs to be monitored, as you know. Hope this helps. ...Read more

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What are the effects of a sickle cell patient using hydroxyurea in the long term?

What are the effects of a sickle cell patient using hydroxyurea in the long term?

Side Effects: There are some serious, but rare, side effects with hydroxyurea, including secondary leukemia, pulmonary fibrosis, pancreatitis, and peripheral neuropathy, or damage to the nerves. Discuss the benefits of decreasing the severity and length of the sickle cell attacks, and the risk of rare side effects as above. ...Read more

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How long can you safely take hydrea (hydroxyurea)?

How long can you safely take hydrea (hydroxyurea)?

Risks vs. Benefits: Hydroxyurea is used to treat sickle cell anemia and some leukemias (blood cancers). As will most medications, there is no official time limit. A medicine that is helpful, is doing a good job, has no equal alternative, and thus is needed, can be used until it is no longer needed. The doctor can explain the risks of "not treating" and of drug side effects, versus the benefits of using hydroxyurea. ...Read more

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What is hydrea (hydroxyurea) usually used to treat?

Many diseases: This antimetabolite has been used for >100yrs in treating benign & malignant conditions including sickle cell disease, essential thrombocytosis, p. Vera, cml, prostate cancer, psoriasis, & even aids. ...Read more

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Can you tell me about hydroxyurea 500 mg availability?

Available: 500mg oral tab of hydroxyurea is available in US. Is that your question? . The dosing of hydroxyurea, however, should be monitored by a doctor. ...Read more

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My dad has to take hydroxyurea. Why?

My dad has to take hydroxyurea. Why?

Blood disorder: My suspicion is that he has a blood disorder called a myeloproliferative neoplasm. His bone marrow is probably making too many of one or more cells. This medication treats this to prevent any complications of over production. Hope this helps. ...Read more

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Are hydroxyurea and clexane usually given together?

Are hydroxyurea and clexane usually given together?

Depends on situation: What is the reason Hydroxyurea is being given? One use of Hydroxyurea is to treat resistant chronic myelocytic leukemia (cml, a cancer of white blood cells). Cancers increase risk of blood clots (dvt), which can be treated w enoxaparin (clexane) in such a case, both would be given. If in hospital, meds like enoxaparin can be used to prevent dvt. Other scenarios exist in which both could be used. ...Read more

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Is Hydroxyurea allowable /applicable for a 1 yr e beta thallassemia baby? Pls advice..

Is Hydroxyurea allowable /applicable for a 1 yr e beta thallassemia baby? Pls advice..

Unclear: I don't see any reliable information on using hydroxyurea under the age of 2 for decreasing transfusion needs in beta thalassemia babies. ...Read more

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What does small amounts of hydroxyurea in blood mean?

Treatment/exposure: Hydroxyurea is a drug used to treat certain blood disorders, some cancers, and HIV disease. If you not on this medicine you may be exposed to it in other ways such as handling it for a loved one. If neither is the case, please consult a healthcare provider asap. ...Read more

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Can hair relaxers cause a problem if taking hydroxyurea?

I do tink so: Drug interactions
there are no data on concomitant use of Hydroxyurea with other drugs in humans. ...Read more

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My mom was prescribed mylocel (hydroxyurea). How does that work?

Antimetabolite: Mylocel, or hydroxyurea, is a form of chemotherapy that works to lower blood counts particularly in patients with leukemia such as chronic myelogenous leukemia and myeloproliferative disorders including polycythemia rubra vera and essential thrombocytosis. Short term side effects may include nausea, hair loss, diarrhea, poor appetite, and nail thickening. Long term effects may include infertility. ...Read more

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Pls advice about the standard /perfect age to taking Hydroxyurea of a e beta thallassemia child?

1 month old: Homozygous hemoglobin E disease (genetic; inherited from both parents) gives mild beta thalassemia & anemia & mildly enlarged spleen; probably doesn't need treatment. Hgb E beta thalassemia disease (E from 1 parent, beta thal from the other): severe incurable disease. Hydroxyurea safe in infants. My guess: start early as possible after 1 mo old. Do discuss this with your pediatric hematologist. ...Read more

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"Hydroxyurea may affect fertility (ability to have children), whether a man or a woman."Please advice..

"Hydroxyurea may affect fertility (ability to have children), whether a man or a woman."Please advice..

Chemotherapy: It is a chemotherapy drug (a mild one, that doesn't have severe side effects, once it has been checked, worries about it lowering blood counts too much are not much).

It does lower sperm quality and that effect can last after it is stopped.
http://www. Ncbi. Nlm. Nih. Gov/pubmed/17316339 ...Read more

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Can hydroxyurea prevent priapism?

Let me try: Priapism is a rare condition which causes a persistent, and often painful, penile erection.
An antineoplastic drug (hydroxyurea) may prevent future episodes of priapism for patients with sickle cell disease. ...Read more

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Could hydroxyurea raise your pulse rate?

Could hydroxyurea raise your pulse rate?

Possibly: High pulse rate (tachycardia) is not reported as a common side effect of hydroxyurea, but if your red blood cell count drops as a side effect, your heart rate may increase in order to increase the oxygen delivery to your tissues. ...Read more

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Does taking durea (hydroxyurea) reduces platelets count?

It can: Reduction in white blood cell count usually occurs before platelet count decreases. See this site for more info on side effects.

http://www. Mayoclinic. Org/drugs-supplements/hydroxyurea-oral-route/side-effects/DRG-20068109 ...Read more

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How long can a patient take hydroxyurea for primary essential thrombocytosis?

As long as it works: This medication has been studied for a long time. There has been no reported cases of secondary cancers directly related to hydrea (hydroxyurea). It just needs to be monitored, as you know. Hope this helps. ...Read more

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I have (et) how high can platelets get before you recommend meds like hydrea (hydroxyurea)?

I have (et) how high can platelets get before you recommend meds like hydrea (hydroxyurea)?

ET: When deciding whether to recommend hydrea, (hydroxyurea) the md takes into account patient's age, underlying cardiovascular risk factors, ; prior history of blood clots. The number of platelets is irrelevant if a patient is otherwise healthy. I have plenty of patients with platelet counts around 1 million. Look for an article from blood journal called "how I treat essential thrombocythemia" for a good summary. ...Read more

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Is there any chances of getting cancer if the normal person takes hydroxyurea or anagrelide more than a month?

Is there any chances of getting cancer if the normal person takes hydroxyurea or anagrelide more than a month?

I say no: The talk of an increased leukemia risk has been with us since the 1970s without anybody being able to measure it. If it's real, it's tiny. Anagrelide isn't under suspicion. If some overzealous practitioner went after a high platelet count without good reason, I'm sorry but you'll be fine. Why do you ask? ...Read more

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If a PLT is normal but starts to fall (even getting down to 8) & this is suspected to be a drug effect (Hydroxyurea) & the drug is ceased & the low PLT resolves itself within 7 days then would an undetected infection stop the PLT from normalising?

If a PLT is normal but starts to fall (even getting down to 8) & this is suspected to be a drug effect (Hydroxyurea) & the drug is ceased & the low PLT resolves itself within 7 days then would an undetected infection stop the PLT from normalising?

May I assume that: You're referring to your platelets and that they got down to 80, 000? If not, you can ignore this response! Hydroxyuria can interfere with the production of platelets and discontinuing it may allow the platelet count to return to normal. An "undetected infection" shouldn't, by itself, prevent the platelets from normalizing, especially if they've already done so. Dr. Anne ...Read more

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Can one drink alcohol while taking hydroxyurea?

Can one drink alcohol while taking hydroxyurea?

Yes, but...: In moderation, there should be no interaction between alcohol and hydroxyurea. If you take Hydroxyurea for sickle cell anemia, you should be careful with alcohol because alcohol can lead to dehydration which can precipitate a sickle crisis. ...Read more

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What are the symptoms of sickle cell disease- hydroxyurea?

Well tolerated drug.: Hydrea (hydroxyurea) is a chemotherapy like drug that can help prevent painful crises in patients with sickle cell disease. It is well tolerated for the most part. There can be fatigue, mouth sores and loose stools. It will routinely lower the white blood cell count and platelets, but not to dangerous levels. Hemoglobin may actually improve. There is? Of leukemia risk in other diseases, but not in scd. ...Read more

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Can Hydroxyurea cause polycythemia vera to mutate into leukemia?

Controversial: There is a risk of transformation to acute leukemia just from having P Vera. But it is very low. Whether hydroxyurea increases that risk has not be definitively answered. Most hematologists find the benefit of controlling the disease greatly outweighs the risk. There is a new drug - Jakafi (ruxolitinib) - just approved for PV if not well controlled or if side effects of HU too great. Talk to your hematologist. ...Read more

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Can hydrea (hydroxyurea) be used to help children with sickle cell disease?

Yes: In the treatment of sickle-cell disease, hydroxycarbamide increases the concentration of fetal hemoglobin. The precise mechanism of action is not yet clearbut it seems to activate of gammaglobin synthesis necessary for fetal hemoglobin. This stops the rapidly growing cells that turn into sickle cells. ...Read more

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Could hydrea (hydroxyurea) possibly help children with sickle cell disease?

Yes: Hydre increases a type of hemoglobin called fetal hemoglobin in sicle cell patients and this prevents the sickle cells from breaking up easily. Hydrea (hydroxyurea) can reduce need for transfusions and patients may have less pain crises, chest sydrome and other complications. ...Read more

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How long does anagrelide or hydroxyurea takes time to reduces platelet counts?

How long does anagrelide or hydroxyurea takes time to reduces platelet counts?

Half life of platele: The half life time (t/2) is the number of days that needed to reduce the platelet count to half its number.
the platelet T/2 is 7-10 days.
in other words it needs 7-10 days to see effect of the drugs (if the drug is working) ...Read more

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What will happen if healthy person took hydroxyurea. Does it decreases platelet count?

Hydroxyurea: Hydroxyurea is a chemotherapy drug and should not be used in healthy people. It will cause suppression of the bone marrow that can lead to low white blood cells, anemia (low red blood cells) and also low platelets. It is a potentially dangerous medication that should only be used as prescribed by a physician. ...Read more

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Can homeopathy bring additional benefits to thalassemic patients on hydrea (hydroxyurea)?

Can homeopathy bring additional benefits to thalassemic patients on hydrea (hydroxyurea)?

No: Truly homeopathic "medications" are made by repeated dilutions, so that the ingredient is not really in the medication anymore (just the "essence" of it remains). That means there is no active ingredient left to cause any benefit. However, that also implies that the homeopathic "medicine" should be pretty harmless, unless some other non-homeopathic ingredients were added. ...Read more

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Will hydroxyurea cause excessive sweating?

Not realy: On one hand: Hydroxyurea does not cause excessive sweatingexcessive sweating is not one of the side effects associated with taking hydroxyurea, a medication used in the treatment of some types of cancer, according to the mayo clinic and medline plus. ...Read more

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Is hydroxyurea a cure for chronic lymphocytic leukemia?

Is hydroxyurea a cure for chronic lymphocytic leukemia?

Cure?: There are many treatnents used to treat cll. However the only therapy that may be curative is a stem cell or bone marrow transplant from a donor. ...Read more

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Could hydroxyurea therapy cause leukemia and/or lymphoma among patients?

Possibly: The agent is considered mutagenic and although the risk is low, it is a real one. ...Read more

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Is Hydroxyurea Therapy helpful for E Beta Thalassemia patient? Pls advice..

Hydroxyurea: The use of hydroxyurea may help in cutting down the number of transfusions needed ...Read more

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