Doctor insights on:
High Islet Cell Antibody
Means nothing alone: Please forgive my frankness. This mishmash of lab results is meaningless apart from your history and physical exam. Reference ranges for labs are set so that a few percent of healthies fall outside on either end. If you feel well, ignore them. The high hs-CRP may be a heads-up that you've got more atherosclerosis than you think. If you feel well, ignore the rest. ...Read more
Blood flow cytmtry shows dual positive cd4cd30 cells absolute count of 2354. IGG slightly elevated with elevated light chains, T cell Beta clone noted?
Asking what?: If your are requesting a diagnosis online, this is not the appropriate venue. Though the flow cytometry results are not totally normal, your results should be reviewed with the physician who ordered it. This format does not give us the ability to determine if your clinical presentation and lab results are consistent with a specific diagnosis. ...Read more
Tumor: Monoclonal proliferation of lymphoid cells is usually an indication of tumor of the lymphoid tissue. ...Read more
Slightly elevated beta fraction from serum protein electrophoresis. Beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen. Immunofixation normal.
Cells vs, animals: A monoclonal antibody is produced by in-vitro manipulation by expoanding a single cell making a desired antibody. Polyclonal antibodies are usually derived from immunizing an animal and colletcting its blood/serum containing the antibody. Polyclonal antibodies are a mixture of a large number of different cells. ...Read more
Adnorm. Blood & cfs results: high: CSF protein-47, high cfs albumin-30.9; low total protein-5.7, low gamma globulin-.5, low IgG quantitative -621 worry?
CSF: Some experts consider CSF protein levels to be normal if the value is equal to or below your age in years. I don't think in your case there is a reason to worry. Other CSF components are important as well. Check with your physician to see if there is any reasons to worry. Hope you feel well soon. ...Read more
my WBC was high absolute neutrophils and absolute basophils high absolute lymphocytes were low. As well CD3, helper cells cd4 cd 19 low cd15 16 hig?
Immunofixation, Serum FAH = Monoclonal IgG kappa immunoglobulin. Beta FAH = 10.5% Abnormal band, immunofixation to follow. I'm IgA deficient too. ??
Possibly: If I am understaning this right you have a monoclonal protien band? The most important next steps here would be to identify the band (immunofixation) and then perfrom quantitvaive immunoglobulin levels. IF there is a monoclonal band, you may very well have reciprocal depriciation of alternative immunoglobulins and IgA deficiecny with an IgG monoclonal protein is possible. ...Read more
Not necessarily....: Patients with sickle cell disease have elevated reticulocyte counts at baseline, as their red cells have significantly reduced half lives relative to normal rbcs. More rapid red cell synthesis, reflected by the high retic count, is needed to maintain steady state, albeit lower than normal. Are you having other symptoms suggesting vaso occlusive crisis? If so, you should seek medical attention. ...Read moreSee 1 more doctor answer
Mild increase = yes: Any stress can trigger an increase in adrenal stress hormone levels. This cortisol can drive white cells off their resting place on the inside walls of blood vessels producing a transient rise in the total white count when they enter the circulation. The effect is transient ...Read more
What would b the cause of chronic high T cell counts, cd4, 5, 7, and 8. A T-cell beta gene rearrangement, elevated IGG, elevated LGL's, but normal CBC?
Reason for doing it: What was the reason you got this done. In all patients we don't do T cell count, Immunoglobulin level estimation etc. What were your symptoms. Based on your answerc an give a better explanation. In any patient we do CBC- complete blood count with differential count.Only in people with suspected immunodeficiencies/hematological problems-dyscrasias is the term we use, detailed Tcell,B cell ,Ig done ...Read more
Thyroid Peroxidase Antibodies 274.0
Anti-Thyroglobulin Antibody 164.4
Mean Platelet Volume 9.1
Erythrocyte Sed Rate 26
Estimat Glomerular Filtratio 43?
High KAPPA/LAMBDA LIGHT CHAIN/slightly high ratio.No Monoclonal protein immunofixation or serum electrophoresis. Is this a type of cancer?Normal WBC
Increased aldolase, complement c3/c4 serum, sed rate, c-react. Protein, beta globulin, monocytes, bun/creatin low mcv-mch, vit d-possible causes?
Complicated: When i was doing clinical medicine, these were collectively sort of the flags for sarcoid disease but I am not saying that's the case here. This is because sarcoid is a diagnosis of exclusion so the advice is to rule out other diseases with additional diagnostic tests which can be done by a primary care physician or rheumatologist. ...Read more
Is elevated kappa/lambda ratio on serum FLC test inherently monoclonal, even if neither kappa or lambda is elevated? Ratio high b/c lambda is low, not because of high kappa. SPEP/UPEP & IFE normal. High IgA, low IgG. Clean marrow biopsy. Polyclonal?
Clinical context : The use of light chains is limited in diseases other than monoclonal gammopathies, such as myeloma or amyloidosis. If this is the context that yours got checked the results do not suggest such a condition. With no gammopathy suggested by results the question regarding clonality has no grounds. As any other test, trending the results would help in integrating it in a meaningful clinical context. ...Read moreSee 1 more doctor answer
Monoclonal T cell beta gene rearrangement in blood /normal CBC / ANA / CMP / high Uric acid. Bouts of itching and hives. Significance?
?: Can still be chronic idiopathic urticaria, but other lab tests need to be performed as well: thyroid function tests, thyroid antibodies, complement levels, stools analysis, etc.. also other pieces of history need to be known, better see an allergist, check aaaai.org or acaai.org for an allergist in your area, meanwhile keep taking whatever antihistaminic on regulat basis, good luck ...Read more
What does a positive NEUTROPHIL CYTOPLASMIC AB.CLASSIC & NEUTROPHIL CYTOPLASMIC AB.PERINUCL & Antinuclear antibodies mean?
See details: This test must be evaluated in the context of the clinical picture. The pANCA and MPO can be positive in several different diseases. ...Read more
Unexplained high platelets (572), WBC (17.2), leukocytes, neutrophils, low hemaglobin. Bone marrow, jak2 and lupus test negative, ANA positive. Help?!
Reactive/ autoimmune: Discuss further with your hematologist. Certain conditions like iron deficiency , infection /inflammation vs autoimmune vs. Other solid tumor need to be ruled out. Need to check iron level, bcr/abl, imaging study like ct scan chest /abd/ pelvis will be needed. If you smoke - will suggest you to quit smoking., need to do work - up to find the anemia as well. If iron is low - GI w/u is needed. ...Read moreSee 2 more doctor answers
Ebv capsid ab IgG 1:580. Positive ccp antibody igg, sed rate, high RDW and mpv on cbc.Liiver alt, AST elevated. Any ideas?
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