Doctor insights on:
Hla Typing For Celiac Disease
My 34 yr old sister had an hla typing for celiac disease and came back positive for hla dq2.Should she be concerened? Is this something serious?
In celiac disease, the body reacts to gluten (in wheat and gluten-like proteins in rye and barley) resulting in damage to the small intestine. This limits the intestine's ability to absorb some nutrients. Typically, people with celiac disease have loose stools, bloating, abdominal pain or discomfort, weight loss, poor weight gain ...Read more
Lower abdominal discomfort, ultra/ct scans, bloodwork, esr, pst, colonoscopy, celiac hla typing, celiac panel all normal. Can it be ativan (lorazepam) withdrawal?
It is nonspecific sy: Your symptoms are not anything serious to justify anymore testing, as you already have done a lot. I would hold off any further interventions and eat and live normally. Begin to exercise daily would help to get your mind of this vague symptom of abdominal discomfort. ...Read more
HLA typing: Describes the determination of proteins on the cell surface which the immune system utilizes to assign self and not self. There are multiple genes which encode these proteins on chromosome 6. ...Read more
Donor-Recipient: These are all methods of determining compatibility between donor and recipient with organ and tissue transplants. Everyone has certain protein and carbohydrate markers on the outside of every cell. These make us unique, but also are potential allergens between people. To help prevent rejection (which can be life-threatening) we try to make sure the markers are alike as possible in both people. ...Read moreSee 1 more doctor answer
In the arena of stem: Cell transplantation this is more defined than in the past. Class one match (hla a, b and c) and class two (hla dr and dq) are all performed at high resolution (gene level tryping). The best match with all loci evaluated will produce the lowest chance of graft rejection. Mis-match can be assessed in the gvhd and host vs graft (rejection) direction. ...Read more
Genetics; eat gluten: Celiac disease (gluten allergy) occurs in a person who may have a genetic tendency to react abnormally to gluten (a protein in wheat, barley, and rye). Something causes his immune system to over-react to gluten. Later, when he eats foods containing gluten, his immune system reacts with the intestine that is digesting the gluten, and causes intestinal damage, abnormal digestion, plus malabsorption. ...Read moreSee 1 more doctor answer
DH: Board Question? Dermatitis Herpetiformis. This appears as a group of itchy blisters, usually on the outside of arms and legs, that can look like herpes. Rarely it can be confused by eczema. Far more people have eczema, though. DH is diagnosed by direct immunofluorescence done via biopsy by a dermatologist. Other conditions can associate with DH as well. ...Read more